Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Darren Tomlinson"'
Autor:
Oliver Debski-Antoniak, Alex Flynn, David P. Klebl, Moisés H. Rojas Rechy, Christian Tiede, Ian A. Wilson, Stephen P. Muench, Darren Tomlinson, Juan Fontana
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT Influenza A virus (IAV) is well known for its pandemic potential. While current surveillance and vaccination strategies are highly effective, therapeutic approaches are often short-lived due to the high mutation rates of IAV. Recently, monoc
Externí odkaz:
https://doaj.org/article/988bf05e653249ae9274081613bd91c1
Autor:
Natalie J. Kingston, Keith Grehan, Joseph S. Snowden, Mark Hassall, Jehad Alzahrani, Guido C. Paesen, Lee Sherry, Connor Hayward, Amy Roe, Sam Stephen, Darren Tomlinson, Antra Zeltina, Katie J. Doores, Neil A. Ranson, Martin Stacey, Mark Page, Nicola J. Rose, Thomas A. Bowden, David J. Rowlands, Nicola J. Stonehouse
Publikováno v:
mSphere, Vol 8, Iss 1 (2023)
ABSTRACT Having varied approaches to the design and manufacture of vaccines is critical in being able to respond to worldwide needs and newly emerging pathogens. Virus-like particles (VLPs) form the basis of two of the most successful licensed vaccin
Externí odkaz:
https://doaj.org/article/b7c301ef9e3a4446bd7a97505024123b
Autor:
Francine Parker, Anna A. S. Tang, Brendan Rogers, Glenn Carrington, Cris dos Remedios, Amy Li, Darren Tomlinson, Michelle Peckham
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Dilated Cardiomyopathy is a common form of heart failure. Determining how this disease affects the structure and organization of cardiomyocytes in the human heart is important in understanding how the heart becomes less effective at contraction. Here
Externí odkaz:
https://doaj.org/article/cc6a0c4d5c4f4d3485748c72de4d581d
Autor:
Julia S. Gauer, Cédric Duval, Rui-Gang Xu, Fraser L. Macrae, Helen R. McPherson, Christian Tiede, Darren Tomlinson, Steve P. Watson, Robert A.S. Ariëns
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:667-681
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e639c3fdd9593ca0b999827c68d5064
https://doi.org/10.1016/j.jtha.2022.09.004
https://doi.org/10.1016/j.jtha.2022.09.004
Autor:
Arindam Pramanik, Zexi Xu, Shazana H. Shamsuddin, Yazan S. Khaled, Nicola Ingram, Thomas Maisey, Darren Tomlinson, P. Louise Coletta, David Jayne, Thomas A. Hughes, Arwen I. I. Tyler, Paul A. Millner
Publikováno v:
ACS Applied Materials & Interfaces. 14:11078-11091
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f50bc8db1f49ad17e760a7b145691a
https://doi.org/10.1021/acsami.1c21655
https://doi.org/10.1021/acsami.1c21655
Autor:
Paul Cordell, Glenn Carrington, Alistair Curd, Francine Parker, Darren Tomlinson, Michelle Peckham
Antibodies are the most widely used, traditional tool for labelling molecules in cells. In the past five to ten years, many new labelling tools have been developed with significant advantages over the traditional antibody. Here, we focus on nanobodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3e2e8c8e098184a1c0dc535c55a30f
https://eprints.whiterose.ac.uk/189297/1/jcs259168.pdf
https://eprints.whiterose.ac.uk/189297/1/jcs259168.pdf
Autor:
Natalie J Kingston, Keith Grehan, Joseph S Snowden, Mark Hassall, Jehad Alzahrani, Guido C Paesen, Lee Sherry, Connor Hayward, Amy Roe, Sam Stephen, Darren Tomlinson, Antra Zeltina, Katie J Doores, Neil A Ranson, Martin Stacey, Mark Page, Nicola J Rose, Thomas A Bowden, David J Rowlands, Nicola J Stonehouse
Having varied approaches to the design and manufacture of vaccines is critical in being able to respond to worldwide needs and to newly emerging pathogens. Virus-like particle (VLP) vaccines form the basis of two of the most successful licensed vacci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0345f2318ac7709ebb7dabbc45162e8e
https://doi.org/10.1101/2022.04.22.489148
https://doi.org/10.1101/2022.04.22.489148
Autor:
Pin Ren, Christian Tiede, Sean W. Fanning, Thomas Adams, Valerie Speirs, Erik R. Nelson, Changfeng Cheng, Terry W. Moore, Geoffrey L. Greene, Darren Tomlinson, Paul R. Selvin
Publikováno v:
Biophysical journal. 121(19)
Mutations of the intracellular estrogen receptor alpha (ERα) is implicated in 70% of breast cancers. Therefore, it is of considerable interest to image various mutants (L536S, Y537S, D538G) in living cancer cell lines, particularly as a function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7555b473b603dd399ce4541b6baf6317
https://pubmed.ncbi.nlm.nih.gov/35778844
https://pubmed.ncbi.nlm.nih.gov/35778844
Autor:
Weili, Wang, Yuan, Guo, Christian, Tiede, Siyuan, Chen, Michal, Kopytynski, Yifei, Kong, Alexander, Kulak, Darren, Tomlinson, Rongjun, Chen, Michael, McPherson, Dejian, Zhou
Publikováno v:
ACS Applied Materials & Interfaces
An ultraefficient cap-exchange protocol (UCEP) that can convert hydrophobic quantum dots (QDs) into stable, biocompatible, and aggregation-free water-dispersed ones at a ligand:QD molar ratio (LQMR) as low as 500, some 20–200-fold less than most li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8da9a51b2040af0ecaa1cdcc7b805b5
https://pubmed.ncbi.nlm.nih.gov/28421739
https://pubmed.ncbi.nlm.nih.gov/28421739
Publikováno v:
Advances in Urology
Advances in Urology, Vol 2012 (2012)
Advances in Urology, Vol 2012 (2012)
Fibroblast growth factors (FGFs) orchestrate a variety of cellular functions by binding to their transmembrane tyrosine-kinase receptors (FGFRs) and activating downstream signalling pathways, including RAS/MAPK, PLCγ1, PI3K, and STATs. In the last t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35c93f0dd41534ce8473bb595d0d760
https://pubmed.ncbi.nlm.nih.gov/22899908
https://pubmed.ncbi.nlm.nih.gov/22899908