Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Darren Tabechian"'
Autor:
Garrett Dunlap, Aaron Wagner, Nida Meednu, Ruoqiao Wang, Fan Zhang, Jabea Cyril Ekabe, Anna Helena Jonsson, Kevin Wei, Saori Sakaue, Aparna Nathan, Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network, Vivian P. Bykerk, Laura T. Donlin, Susan M. Goodman, Gary S. Firestein, David L. Boyle, V. Michael Holers, Larry W. Moreland, Darren Tabechian, Costantino Pitzalis, Andrew Filer, Soumya Raychaudhuri, Michael B. Brenner, Juilee Thakar, Andrew McDavid, Deepak A. Rao, Jennifer H. Anolik
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Rheumatoid arthritis (RA) is an autoimmune disease involving antigen-specific T and B cells. Here, we perform single-cell RNA and repertoire sequencing on paired synovial tissue and blood samples from 12 seropositive RA patients. We identify
Externí odkaz:
https://doaj.org/article/b76b85a9921847d4919133eeb47ed023
Autor:
Andrew Filer, Michael H Weisman, Judith A James, Kenneth Kalunian, Michelle A Petri, Chaim Putterman, H Michael Belmont, Ilfita Sahbudin, Karim Raza, Maria Dall'Era, Jill P Buyon, Diane L Kamen, Karen Salomon-Escoto, Kazuyoshi Ishigaki, Patrick Dunn, David Wofsy, Michele Bombardieri, Vivian Bykerk, Myles Lewis, Ming Wu, Soumya Raychaudhuri, Hemant Suryawanshi, Thomas Tuschl, Christopher Ritchlin, Maureen McMahon, Jennifer Grossman, Philip M Carlucci, Alessandra Nerviani, Peter M Izmirly, Fan Zhang, Felice Rivellese, Joan Bathon, Zhu Zhu, Qian Xiao, Jessica Li, Holden Maecker, Nir Hacohen, Rong Mao, Jennifer Anolik, Javier Rangel-Moreno, Nida Meednu, Susan Goodman, Lindsy Forbess, Mariko Ishimori, Kevin Deane, David Hildeman, Yuhong Li, Laura Hughes, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Larry Moreland, Harris Perlman, Peter Gregersen, Celine C Berthier, Andrea Fava, David Boyle, Derek M Fine, Ami Ben-Artzi, P J Utz, Melanie Smith, Beatrice Goilav, Carla Cuda, Andrew McDavid, Deepak A Rao, Joshua Keegan, Ilya Korsunsky, Joel Guthridge, Kevin Wei, Arnon Arazi, Thomas Eisenhaure, Michael Brenner, Susan Macwana, Pavel Morozov, Manjunath Kustagi, Gerald Watts, Kristina K Deonaraine, Jose Monroy-Trujillo, Mohamed G Atta, Kristin Haag, William Apruzzese, Sean Connery, Fernanda Payan-Schober, Kerry Cho, Jennifer Goff, Aparna Nathan, Joseph Mears, Nghia Millard, Kathryn Weinand, Saori Sakaue, Bill Robinson, Wade DeJager, Louis Bridges, Laura Donlin, Edward DiCarlo, Amit Lakhanpal, Heather Sherman, Anvita Singaraju, Lorien Shakib, Brendan Boyce, Darren Tabechian, Jen Albrecht, James Lederer, A Helena Jonsson, Daimon Simmons, Gregory Keras, Adam Chicoine, Zhihan Jian Li, Mandy McGeachy, Gary Firestein, Arnold Ceponis, Diane Horowitz, Salina Dominguez, Arthur Mandelin, Anjali Thakrar, Mike Holers, Jennifer Seifert, Constanino Pitzalis, Ellen Gravallese, Jennifer Barnas, Raymond Hsu, Steven Woodle, Paul Hoover, Michael Peters, Tony Jones, David Lieb, Jeffrey Hodgin, Raji Menon
Publikováno v:
Lupus Science and Medicine, Vol 8, Iss 1 (2021)
Objectives In lupus nephritis the pathological diagnosis from tissue retrieved during kidney biopsy drives treatment and management. Despite recent approval of new drugs, complete remission rates remain well under aspirational levels, necessitating i
Externí odkaz:
https://doaj.org/article/e3722c73b6ce45bba6e56c13af3b5745
Autor:
Alexander Rosenberg, Hongtao Fan, Yahui G Chiu, Rebecca Bolce, Darren Tabechian, Rick Barrett, Sharon Moorehead, Frédéric Baribaud, Hao Liu, Nancy Peffer, David Shealy, Edward M Schwarz, Christopher T Ritchlin
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110657 (2014)
The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distinct. The ai
Externí odkaz:
https://doaj.org/article/df2006accc4a4e249561d99eb8162ec1
Autor:
Marcy B. Bolster, Darren Tabechian, Bethany Marston, Edwin A. Smith, Ellen Goldmuntz, Richard M. Keating, Lynette Keyes-Elstein, Jeffrey R. Curtis, Andreea Coca, Karen D. Boyle, Nida Meednu, Jennifer H. Anolik, Jennifer Barnard, Ralf G. Thiele, Jonathan Graf, Beverly Welch, Meggan Mackay, Kelly Callahan
Publikováno v:
Arthritis & Rheumatology. 74:200-211
Objective B cells can become activated in germinal center (GC) reactions in secondary lymphoid tissue and ectopic GCs in synovium in RA that may be TNF and lymphotoxin (LT) dependent. Here we characterized the peripheral B cell compartment longitudin
Autor:
Fan Zhang, Darren Tabechian, Brendan F. Boyce, William Apruzzese, Deepak A. Rao, Laura B. Hughes, Amp Ra, Ellen M. Gravallese, Soumya Raychaudhuri, Edward F. DiCarlo, James A. Lederer, Laura T. Donlin, Larry W. Moreland, Peter K. Gregersen, Susan M. Goodman, Andrew Filer, Gerald F. Watts, Harris Perlman, V. Michael Holers, Kamil Slowikowski, Sle, David L. Boyle, Gary S. Firestein, Costantino Pitzalis, Michael B. Brenner, Vivian P. Bykerk, Chad Nusbaum, Arthur M. Mandelin, Kevin Wei, Karen Salomon-Escoto, Jennifer H. Anolik, Stephen Kelly, Chamith Y. Fonseka, Accelerating Medicines Partnership: Ra Phase, David J. Lieb, Nir Hacohen
To define the cell populations in rheumatoid arthritis (RA) driving joint inflammation, we applied single-cell RNA-seq (scRNA-seq), mass cytometry, bulk RNA-seq, and flow cytometry to sorted T cells, B cells, monocytes, and fibroblasts from 51 synovi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6f979872f8341efb91a94607bec556
https://doi.org/10.1101/351130
https://doi.org/10.1101/351130
Autor:
Rany al Haj, Peter C. Grayson, Gurjit S. Kaeley, Darren Tabechian, Amy Evangelisto, Amy C. Cannella, Janak R. Goyal, Eugene Y. Kissin, Daniel G. Malone, Paul J. DeMarco, Jay B. Higgs, Midori Jane Nishio
Publikováno v:
Arthritis Care & Research. 66:2-6
Objective To determine the reliability and validity of an objective structured clinical examination (OSCE) for musculoskeletal ultrasound (MSUS). Methods A 9-station OSCE was administered to 35 rheumatology fellows trained in MSUS and to 3 expert fac
Publikováno v:
Journal of Clinical Neuromuscular Disease. 9:356-360
Sensory neuronopathy in association with connective tissue disease is a disabling disorder for which there is no well-established therapy. Various immunosuppressive agents, plasmapheresis, and intravenous immunoglobulin have shown only anecdotal or m
Autor:
David Shealy, Edward M. Schwarz, Rick Barrett, Darren Tabechian, Hongtao Fan, Sharon Moorehead, Yahui G. Chiu, Christopher T. Ritchlin, Rebecca Bolce, Frédéric Baribaud, Alexander F. Rosenberg, Nancy Peffer, Hao Liu
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110657 (2014)
PLoS ONE
PLoS ONE
Objective The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distin
Autor:
Eugene Y, Kissin, Peter C, Grayson, Amy C, Cannella, Paul J, Demarco, Amy, Evangelisto, Janak, Goyal, Rany, Al Haj, Jay, Higgs, Daniel G, Malone, Midori J, Nishio, Darren, Tabechian, Gurjit S, Kaeley
Publikováno v:
Arthritis careresearch. 66(1)
To determine the reliability and validity of an objective structured clinical examination (OSCE) for musculoskeletal ultrasound (MSUS).A 9-station OSCE was administered to 35 rheumatology fellows trained in MSUS and to 3 expert faculty (controls). Pa
Autor:
Annamaria Iagnocco, Gurjit S. Kaeley, Richard J. Wakefield, Wolfgang A. Schmidt, Nanno Swen, Robert W. Ike, Carlos Pineda, Janak R. Goyal, Esperanza Naredo, Mei Yang, Alvin F. Wells, Ingrid Möller, Peter V. Balint, Jurgen Craig-Muller, George A W Bruyn, Eugene Y. Kissin, Marina Backhaus, Jane Nishio, Maria A. D'Agostino, Alexander Feoktistov, Darren Tabechian
Objective Because musculoskeletal ultrasound (MSUS) is highly user dependent, we aimed to establish whether non-mentored learning of MSUS is sufficient to achieve the same level of diagnostic accuracy and scanning reliability as has been achieved by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53aec1fc93b67e54288d38ac26ca7dd
http://hdl.handle.net/2318/1613112
http://hdl.handle.net/2318/1613112