Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Darren S. Thomas"'
Autor:
Darren S. Thomas, Aaron Y. Lee, Philipp L. Müller, Roy Schwartz, Abraham Olvera‐Barrios, Alasdair N. Warwick, Praven J. Patel, Tjebo F.C. Heeren, Catherine Egan, Paul Taylor, Adnan Tufail, UK AMD EMR Users Group
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 1166-1175 (2021)
Abstract One‐in‐four ophthalmology trials are single‐armed, which poses challenges to their interpretation. We demonstrate how real‐world cohorts used as external/synthetic control arms can contextualize such trials. We herein emulated a targ
Externí odkaz:
https://doaj.org/article/9fbe35aeacef4b1d933837ebbeb96005
Autor:
Philipp L. Müller, Paul Taylor, Roy Schwartz, Praveen J. Patel, Alasdair Warwick, Abraham Olvera-Barrios, Darren S. Thomas, Catherine A Egan, Aaron Y. Lee, Tjebo F. C. Heeren, Adnan Tufail
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 3, Pp 1166-1175 (2021)
Clinical and Translational Science, Vol 14, Iss 3, Pp 1166-1175 (2021)
One‐in‐four ophthalmology trials are single‐armed, which poses challenges to their interpretation. We demonstrate how real‐world cohorts used as external/synthetic control arms can contextualize such trials. We herein emulated a target trial
Autor:
Darren S, Thomas, Alasdair, Warwick, Abraham, Olvera-Barrios, Catherine, Egan, Roy, Schwartz, Sudeshna, Patra, Haralabos, Eleftheriadis, Anthony, Khawaja, Andrew, Lotery, Philipp L, Muller, Robin, Hamilton, Ella, Preston, Paul, Taylor, Adnan, Tufail, E, Wilkinson
Publikováno v:
BMJ Open. 12:e057269
ObjectivesTo report the reduction in new neovascular age-related macular degeneration (nAMD) referrals during the COVID-19 pandemic and estimate the impact of delayed treatment on visual outcomes at 1 year.DesignRetrospective clinical audit and simul
Autor:
Adnan Tufail, Tjebo F. C. Heeren, Andrew J. Lotery, Abdulrahman Alsaedi, Darren S. Thomas, Konstantinos Balaskas, Clara I. Sánchez, Bobby Paul, Narendra Dhingra, Philipp L. Müller, Cristina González Gonzalo, Bart Liefers, Abraham Olvera-Barrios, Clare Bailey, Alasdair Warwick, Paul Taylor, Roy Schwartz, Filipa Rodrigues, Catherine A Egan
Publikováno v:
American Journal of Ophthalmology, 226, 1-12
American Journal of Ophthalmology, 226, pp. 1-12
American Journal of Ophthalmology, 226, pp. 1-12
Contains fulltext : 235480.pdf (Publisher’s version ) (Open Access) PURPOSE: We sought to develop and validate a deep learning model for segmentation of 13 features associated with neovascular and atrophic age-related macular degeneration (AMD). DE
Autor:
Tjebo F. C. Heeren, Catherine A Egan, Adnan Tufail, Darren S. Thomas, Alasdair Warwick, Abraham Olvera-Barrios, Praveen J. Patel, Philipp L. Müller, Paul Taylor, Roy Schwartz, Aaron Y. Lee
Methods of causal inference have shown promise in replicating randomised trials using real-world data recorded by Electronic Health Records (EHRs). We herein emulated a target trial on the intention-to-treat efficacy of off-label bevacizumab (q6w) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98598d0ab8674c23f150cc66589a883
Autor:
Sudeshna Patra, Catherine A Egan, Darren S. Thomas, Abraham Olvera-Barrios, Haralabos Eleftheriadis, Anthony P Khawaja, Andrew J. Lotery, Ella Preston, Alasdair Warwick, Paul Taylor, Roy Schwartz, Robin Hamilton, Adnan Tufail, Philipp L. Mueller
ObjectivesTo report the reduction in new neovascular age-related macular degeneration (nAMD) referrals during the COVID-19 pandemic and estimate the impact of delayed treatment on visual outcomes at one year.DesignRetrospective clinical audit and sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c266e55b7130b959020fb3cce238f4e0
Autor:
Darren S, Thomas, Aleksandra, Gentry-Maharaj, Andy, Ryan, Evangelia-Ourania, Fourkala, Sophia, Apostolidou, Matthew, Burnell, Wendy, Alderton, Julie, Barnes, John F, Timms, Usha, Menon
Publikováno v:
Cancer Epidemiology
Highlights • Ninety-two & 99% of colorectal cancers were registered after one & six years. • Hospital Episode Statistics tend to capture events unregistered after one year. • Self-reporting by women aged ≥50 was less reliable and had low resp
Autor:
Anthony Khawaja, Andrew Lotery, Adnan Tufail, Paul Taylor, Philipp L Müller, Sudeshna Patra, R Khan, E Wilkinson, B Paul, Haralabos Eleftheriadis, Robin Hamilton, S George, V Kumar, R Mukherjee, C Jones, Abraham Olvera-Barrios, Catherine Egan, Roy Schwartz, C Brand, H Palmer, Alasdair Warwick, C Bailey, U Chakravarthy, F Ghanchi, S Mahmood, A Davis, L Downey, G Menon, N Dhingra, R Antcliff, A Lobo, A Patwardhan, T Akerele, Darren S Thomas, Ella Preston, P Lip, S Natha, J Talks
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Objectives To report the reduction in new neovascular age-related macular degeneration (nAMD) referrals during the COVID-19 pandemic and estimate the impact of delayed treatment on visual outcomes at 1 year.Design Retrospective clinical audit and sim
Externí odkaz:
https://doaj.org/article/39f48705e64841e0b30ed6d7b5842eb9