Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Darren S. Heeke"'
Autor:
Jason D Marshall, Darren S Heeke, Eileen Rao, Sean K Maynard, David Hornigold, Christopher McCrae, Neil Fraser, Andrey Tovchigrechko, Li Yu, Nicola Williams, Sarah King, Martin E Cooper, Adeline M Hajjar, Jennifer C Woo
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164632 (2016)
The best-characterized Toll-like receptor 4 (TLR4) ligands are lipopolysaccharide (LPS) and its chemically modified and detoxified variant, monophosphoryl lipid A (MPL). Although both molecules are active for human TLR4, they demonstrate a potency pr
Externí odkaz:
https://doaj.org/article/a7e51b143f2f4c90835b58966e433abe
Autor:
Derek D. Sloan, Roselyn J. Eisenberg, Padmaja Tummala, Michael T Hensel, Jason D. Marshall, Darren S. Heeke, Eileen Rao, Michael R Dorwart, Gary H. Cohen, Li Yu
Several prophylactic vaccines targeting herpes simplex virus 2 (HSV-2) have failed in the clinic to demonstrate sustained depression of viral shedding or protection from recurrences. Although these vaccines have generated high titers of neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c75276a45dbd801a696c7aae5187fab2
https://europepmc.org/articles/PMC5391472/
https://europepmc.org/articles/PMC5391472/
Autor:
Jason D. Marshall, Rui Lin, Michael P. McCarthy, Vera Chio, Darren S. Heeke, Li Yu, Hui Liu, Eileen Rao, Fengrong Zuo, Floro Cataniag
Publikováno v:
Journal of virological methods. 247
The goal of most prophylactic vaccines is to elicit robust and effective neutralizing antibodies against the human pathogen target. The titer of neutralizing antibodies to Epstein-Barr Virus (EBV) is a useful biomarker for evaluating EBV vaccines. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cd21dbd7cfa4028062af1d2f711ab7
https://pubmed.ncbi.nlm.nih.gov/28457783
https://pubmed.ncbi.nlm.nih.gov/28457783
Autor:
Cooper Martin, Darren S. Heeke, Jason D. Marshall, Adeline M. Hajjar, Sarah King, Nicola Williams, Christopher McCrae, Jennifer Woo, Andrey Tovchigrechko, Neil Fraser, Li Yu, Eileen Rao, David C. Hornigold, Sean K. Maynard
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 10, p e0164632 (2016)
PLoS ONE, Vol 11, Iss 10, p e0164632 (2016)
The best-characterized Toll-like receptor 4 (TLR4) ligands are lipopolysaccharide (LPS) and its chemically modified and detoxified variant, monophosphoryl lipid A (MPL). Although both molecules are active for human TLR4, they demonstrate a potency pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5f96ba8f2ea4a4ab92100996384ecd
https://pubmed.ncbi.nlm.nih.gov/27736941
https://pubmed.ncbi.nlm.nih.gov/27736941
Publikováno v:
Vaccine. 34(23)
Childhood infection with Epstein-Barr virus (EBV) is often asymptomatic and may result in mild flu-like symptoms, but exposure during adolescence and young adulthood can lead to acute infectious mononucleosis (AIM) with a pathology characterized by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7daebe0b29d17ddaaaff3a9f9fd6b44a
https://pubmed.ncbi.nlm.nih.gov/27085175
https://pubmed.ncbi.nlm.nih.gov/27085175
Autor:
Chris Frantz, Rui Lin, Fengrong Zuo, Kathryn Patton, Shahin Aslam, Xavier Paliard, Stacie L. Lambert, Darren S. Heeke, Mark T. Esser, Cindy Shambaugh
Publikováno v:
Vaccine. 33(36)
Respiratory syncytial virus (RSV) causes significant disease in elderly adults, but an effective vaccine is not yet available. We have previously reported that vaccines consisting of engineered respiratory syncytial virus soluble fusion protein (RSV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db92ae399a2f3e37d8aa6e3fcdc0689
https://pubmed.ncbi.nlm.nih.gov/26206269
https://pubmed.ncbi.nlm.nih.gov/26206269
Publikováno v:
Immunology. 117:38-46
Immunostimulatory sequences (ISS) that contain CpG motifs have been demonstrated to exert antipathogen and antitumour immunity in animal models through several mechanisms, including the activation of natural killer (NK) cells to secrete interferon-ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc499ec3da1bd692af68b572639d8e1
https://doi.org/10.1111/j.1365-2567.2005.02261.x
https://doi.org/10.1111/j.1365-2567.2005.02261.x
Autor:
Jason Marshall, Marianne L Gesner, Gary Van Nest, Brian S Livingston, Eduardo B. Martins, Darren S. Heeke
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23944f46dc130bd417c5296666495046
https://doi.org/10.1096/fasebj.22.1_supplement.859.12
https://doi.org/10.1096/fasebj.22.1_supplement.859.12
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5903f773018410a738be4030516635c
https://doi.org/10.1096/fasebj.22.1_supplement.856.9
https://doi.org/10.1096/fasebj.22.1_supplement.856.9
Publikováno v:
Journal of leukocyte biology. 82(3)
Toll-like receptors (TLRs) are a family of molecules that function as sensors for the detection of foreign pathogens through the recognition of nonvariable microbial motifs. Although numerous studies have focused on singular TLRs, less attention has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de918b052582d3fea7874e672719c00
https://pubmed.ncbi.nlm.nih.gov/17565046
https://pubmed.ncbi.nlm.nih.gov/17565046