Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Darren R. Williams"'
Publikováno v:
All Life, Vol 16, Iss 01 (2023)
Skeletal muscle comprises the major organ system in our bodies and is the effector tissue for fundamental processes, such as movement, breathing and glucose homeostasis. However, muscle regeneration can be insufficient to repair major injuries or bec
Externí odkaz:
https://doaj.org/article/c30635cf6c3549d5b92084cfb8680fb3
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 3062-3077 (2022)
Abstract Background Skeletal muscle atrophy can occur in response to numerous factors, such as ageing and certain medications, and produces a major socio‐economic burden. At present, there are no approved drugs for treating skeletal muscle atrophy.
Externí odkaz:
https://doaj.org/article/ca4ae4579b3f4a2b95bf7ae6126735c8
Publikováno v:
Clinical and Translational Medicine, Vol 10, Iss 8, Pp n/a-n/a (2020)
Externí odkaz:
https://doaj.org/article/98991610b9134e55aef767eb65de9efc
Autor:
Boryeong Pak, Christopher E. Schmitt, Woosoung Choi, Jun-Dae Kim, Orjin Han, Jessica Alsiö, Da-Woon Jung, Darren R. Williams, Wouter Coppieters, Didier Y. R. Stainier, Suk-Won Jin
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endothelial cells appear to emerge from diverse progenitors. However, to which extent their developmental origin contributes to define their cellular and molecular characteristics remains largely unknown. Here, we report that a subset of endothelial
Externí odkaz:
https://doaj.org/article/587a3acf74fb4c91819292b57473e78b
Autor:
Woong-Hee Kim, Pyeonghwa Jeong, Seon-Wook Kim, Haaglim Cho, Jeong-min Lee, Shinae Seo, Haihong Shen, Youngkeun Ahn, Da-Woon Jung, Yong-Chul Kim, Darren R. Williams
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
This article contains chemical characterization and biological activity data for a novel indirubin derivative, termed LDD-1819. The detailed synthesis procedure and associated NMR data are presented. The concentration-dependent inhibition data of two
Externí odkaz:
https://doaj.org/article/0fa013ca5f0f4d89bb07e90598c18f5c
Autor:
Ji-Hyung Lee, Seon-Wook Kim, Jun-Hyeong Kim, Hyun-Jun Kim, JungIn Um, Da-Woon Jung, Darren R. Williams
Publikováno v:
Cells, Vol 10, Iss 5, p 1017 (2021)
Inflammation-mediated skeletal muscle wasting occurs in patients with sepsis and cancer cachexia. Both conditions severely affect patient morbidity and mortality. Lithium chloride has previously been shown to enhance myogenesis and prevent certain fo
Externí odkaz:
https://doaj.org/article/6bfdc1f09a4a4d91b865c8441ba19800
Autor:
Jiyeon Ha, Hana Jang, Namjeong Choi, Jagyeong Oh, Chanhyuk Min, Davide Pradella, Da-Woon Jung, Darren R. Williams, Daeho Park, Claudia Ghigna, Xuexiu Zheng, Haihong Shen
Publikováno v:
Cells, Vol 10, Iss 3, p 679 (2021)
Alternative splicing (AS) is an important posttranscriptional regulatory process. Damaged or unnecessary cells need to be removed though apoptosis to maintain physiological processes. Caspase-2 pre-mRNA produces pro-apoptotic long mRNA and anti-apopt
Externí odkaz:
https://doaj.org/article/6042f6f5d8524550a785883f7e51c77b
Autor:
Hyun Jung Kim, Soon-Ho Yim, Fubo Han, Bok Yun Kang, Hyun Jin Choi, Da-Woon Jung, Darren R. Williams, Kirk R. Gustafson, Edward J. Kennelly, Ik-Soo Lee
Publikováno v:
Molecules, Vol 24, Iss 3, p 394 (2019)
A metabolic conversion study on microbes is known as one of the most useful tools to predict the xenobiotic metabolism of organic compounds in mammalian systems. The microbial biotransformation of isoxanthohumol (1), a major hop prenylflavanone in be
Externí odkaz:
https://doaj.org/article/a110f312c550460ba5df1bd09af2d300
Publikováno v:
Sensors, Vol 12, Iss 4, Pp 5005-5027 (2012)
Glucose homeostasis is a fundamental aspect of life and its dysregulation is associated with important diseases, such as cancer and diabetes. Traditionally, glucose radioisotopes have been used to monitor glucose utilization in biological systems. Fl
Externí odkaz:
https://doaj.org/article/ebd691831c714aae9d8d538067d51162
Autor:
Woong-Hee Kim, JungIn Um, Youngkeun Ahn, Won Keun Oh, Ah Ra Kim, Da-Woon Jung, Suk-Won Jin, Soon-Ho Yim, Seon-Wook Kim, Hong Seok, Ji-Hyung Lee, Kuk-Hwa Kim, Darren R. Williams, Ba-Wool Lee
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Aging is associated with increased prevalence of skeletal and cardiac muscle disorders, such as sarcopenia and cardiac infarction. In this study, we constructed a compendium of purified ginsenoside compounds from Panax ginseng C.A. Meyer, which is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc5bb4425dafd40676f59a504a57bbe
http://link.springer.com/article/10.1038/s41598-020-61491-4
http://link.springer.com/article/10.1038/s41598-020-61491-4