Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Darren R. Veach"'
Autor:
Michael R. McDevitt, Daniel L. J. Thorek, Takeshi Hashimoto, Tatsuo Gondo, Darren R. Veach, Sai Kiran Sharma, Teja Muralidhar Kalidindi, Diane S. Abou, Philip A. Watson, Bradley J. Beattie, Oskar Vilhemsson Timmermand, Sven-Erik Strand, Jason S. Lewis, Peter T. Scardino, Howard I. Scher, Hans Lilja, Steven M. Larson, David Ulmert
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Radionuclides that emit alpha particles (charged helium nuclei) are currently used clinically to treat cancers including prostate cancer. Here, the authors combine a humanized antibody to an alpha particle emitter, specifically to target a downstream
Externí odkaz:
https://doaj.org/article/02a356c6cc14425c8da1a1e7764743bc
Autor:
Miriam Benezra, Dolores Hambardzumyan, Oula Penate-Medina, Darren R. Veach, Nagavarakishore Pillarsetty, Peter Smith-Jones, Evan Phillips, Tatsuya Ozawa, Pat B. Zanzonico, Valerie Longo, Eric C. Holland, Steven M. Larson, Michelle S. Bradbury
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 12, Pp 1132-1143 (2012)
Dasatinib, a new-generation Src and platelet-derived growth factor receptor (PDGFR) inhibitor, is currently under evaluation in high-grade glioma clinical trials. To achieve optimum physicochemical and/or biologic properties, alternative drug deliver
Externí odkaz:
https://doaj.org/article/2c08ae7489e040099780f8259071fc02
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
S1. Hierarchical clustering based on Euclidean distance of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and untreated (C1-3) samples.S2. Multi-dimensional scaling plot of RNA-seq data demonstrates separation of EBRT-treated (B1-3) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1377f5f545ae64255126d352d870e4e0
https://doi.org/10.1158/1541-7786.22551840
https://doi.org/10.1158/1541-7786.22551840
Autor:
Sarah M. Cheal, Steven M. Larson, Nai Kong V. Cheung, Neeta Pandit-Taskar, Achim Jungbluth, Andrea Cercek, Garrett M. Nash, Sébastien Monette, Pat B. Zanzonico, Brian H. Santich, Hong-fen Guo, Hong Xu, Mitesh Patel, Daniela Burnes Vargas, Blesida Punzalan, Edward K. Fung, Darren R. Veach, Sebastian K. Chung, Meghan M. Bell, Christopher S. Chandler
Peritoneal carcinomatosis (PC) is considered incurable, and more effective therapies are needed. Herein we test the hypothesis that GPA33-directed intracompartmental pretargeted radioimmunotherapy (PRIT) can cure colorectal peritoneal carcinomatosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acef59b9b8016bb1ef603c3ce50fbe38
https://doi.org/10.1158/1535-7163.c.6543270.v1
https://doi.org/10.1158/1535-7163.c.6543270.v1
Autor:
David Ulmert, Daniel Thorek, Hans Lilja, Steven M. Larson, Robert Damoiseaux, Robert J. Klein, Norbert Peekhaus, Wahed Zedan, Diane Abou, Ken Herrmann, Julie E. Park, Teja Kalidindi, Michael R. McDevitt, Gabriel Adrian, Katharina Lückerath, Darren R. Veach, Mesude Bicak, Mohamed Altai, Claire M. Storey
Noninvasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer therapies. AR is a critical driver and mediator of resistance of prostate cancer but currently available no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0445efa2285bf786789e370019ca125b
https://doi.org/10.1158/1541-7786.c.6534810
https://doi.org/10.1158/1541-7786.c.6534810
Autor:
Sarah M. Cheal, Steven M. Larson, Nai Kong V. Cheung, Neeta Pandit-Taskar, Achim Jungbluth, Andrea Cercek, Garrett M. Nash, Sébastien Monette, Pat B. Zanzonico, Brian H. Santich, Hong-fen Guo, Hong Xu, Mitesh Patel, Daniela Burnes Vargas, Blesida Punzalan, Edward K. Fung, Darren R. Veach, Sebastian K. Chung, Meghan M. Bell, Christopher S. Chandler
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4552114e96bd1d8d447a47494ca35371
https://doi.org/10.1158/1535-7163.22522074
https://doi.org/10.1158/1535-7163.22522074
Autor:
David Ulmert, Daniel L.J. Thorek, Michael R. McDevitt, Hans Lilja, Steven M. Larson, Peter Scardino, Howard I. Scher, Dmitry Pankov, Nadia Benabdallah, Pat Zanzonico, Robert Damoiseaux, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Teja Kalidindi, Urpo Lamminmäki, Christian von Bodman, Katharina Braun, Katharina Lückerath, Claire M. Storey, Darren R. Veach
Supplementary Figure S2. Autoradiography of whole mounted KLK3_Hi-MYC GEMM prostate sections obtained 120h p.i. of [89Zr]hu5A10 (A) or [90Y]hu5A10 (B). Radioimmunoconjugate activity was detected in regions expressing PSA, but not in adjacent tissues
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6796d7061d299f00f689299fe6a1e311
https://doi.org/10.1158/1078-0432.22480926.v1
https://doi.org/10.1158/1078-0432.22480926.v1
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
Summary of immunogenicity experiment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66e998a48dfc37d4b7f720c68d19b49
https://doi.org/10.1158/1078-0432.22479494
https://doi.org/10.1158/1078-0432.22479494
Autor:
Nai K. Cheung, Steven M. Larson, Charles M. Rudin, Adam O. Michel, Sebastien Monette, Pat B. Zanzonico, Hong-Fen Guo, Aiza A. Malik, Daniela Burnes Vargas, Mitesh Patel, Edward K. Fung, Darren R. Veach, Guangbin Yang, Ouathek Ouerfelli, Michael R. McDevitt, Mahiuddin Ahmed, Sarah M. Cheal, Brian H. Santich
2-step SADA-PRIT imaging by PET/CT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227c28b24bf83bfd1f7bde02d3209963
https://doi.org/10.1158/1078-0432.22479479.v1
https://doi.org/10.1158/1078-0432.22479479.v1
Autor:
David Ulmert, Daniel L.J. Thorek, Michael R. McDevitt, Hans Lilja, Steven M. Larson, Peter Scardino, Howard I. Scher, Dmitry Pankov, Nadia Benabdallah, Pat Zanzonico, Robert Damoiseaux, Mohamed Altai, Joanna Strand, Sven-Erik Strand, Teja Kalidindi, Urpo Lamminmäki, Christian von Bodman, Katharina Braun, Katharina Lückerath, Claire M. Storey, Darren R. Veach
Supplementary Table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0347ffa75648b5075af7dcfff7ac6a64
https://doi.org/10.1158/1078-0432.22480914.v1
https://doi.org/10.1158/1078-0432.22480914.v1