Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Darren P Martin"'
Autor:
Alexander G Lucaci, Jordan D Zehr, Stephen D Shank, Dave Bouvier, Alexander Ostrovsky, Han Mei, Anton Nekrutenko, Darren P Martin, Sergei L Kosakovsky Pond
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0275623 (2022)
An important unmet need revealed by the COVID-19 pandemic is the near-real-time identification of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. Although powerful molecular sequence analysis methods are available t
Externí odkaz:
https://doaj.org/article/bca1a56d05294988afd66598cded39bb
Autor:
Adérito L Monjane, Simon Dellicour, Penelope Hartnady, Kehinde A Oyeniran, Betty E Owor, Marion Bezuidenhout, Daphné Linderme, Rizwan A Syed, Lara Donaldson, Shane Murray, Edward P Rybicki, Anders Kvarnheden, Elham Yazdkhasti, Pierre Lefeuvre, Rémy Froissart, Philippe Roumagnac, Dionne N Shepherd, Gordon W Harkins, Marc A Suchard, Philippe Lemey, Arvind Varsani, Darren P Martin
Publikováno v:
eLife, Vol 9 (2020)
For pathogens infecting single host species evolutionary trade-offs have previously been demonstrated between pathogen-induced mortality rates and transmission rates. It remains unclear, however, how such trade-offs impact sub-lethal pathogen-inflict
Externí odkaz:
https://doaj.org/article/28baa327e21a451f849d2a0fa0052410
Autor:
Francis E. Agamah, Thomas H. A. Ederveen, Michelle Skelton, Darren P. Martin, Emile R. Chimusa, Peter A. C. ’t Hoen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
BackgroundCOVID-19 disease is characterized by a spectrum of disease phases (mild, moderate, and severe). Each disease phase is marked by changes in omics profiles with corresponding changes in the expression of features (biosignatures). However, int
Externí odkaz:
https://doaj.org/article/da6917fc083f4b01b143c354996d6281
Autor:
Essowè Palanga, Denis Filloux, Darren P Martin, Emmanuel Fernandez, Daniel Gargani, Romain Ferdinand, Jean Zabré, Zakaria Bouda, James Bouma Neya, Mahamadou Sawadogo, Oumar Traore, Michel Peterschmitt, Philippe Roumagnac
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165188 (2016)
Cowpea, (Vigna unguiculata L. (Walp)) is an annual tropical grain legume. Often referred to as "poor man's meat", cowpea is one of the most important subsistence legumes cultivated in West Africa due to the high protein content of its seeds. However,
Externí odkaz:
https://doaj.org/article/a9a85d7bb0cd4d8ea6eccb75ebd918ad
Autor:
Wonderful T. Choga, Gobuiwang Khilly Kurusa (Gasenna), James Emmanuel San, Tidimalo Ookame, Irene Gobe, Mohammed Chand, Badisa Phafane, Kedumetse Seru, Patience Matshosi, Boitumelo Zuze, Nokuthula Ndlovu, Teko Matsuru, Dorcas Maruapula, Ontlametse T. Bareng, Kutlo Macheke, Lesego Kuate-Lere, Labapotswe Tlale, Onalethata Lesetedi, Modiri Tau, Mpaphi B. Mbulawa, Pamela Smith-Lawrence, Mogomotsi Matshaba, Roger Shapiro, Joseph Makhema, Darren P. Martin, Tulio de Oliveira, Richard J. Lessells, Shahin Lockman, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 91-96 (2024)
We investigated intra-host genetic evolution using two SARS-CoV-2 isolates from a fully vaccinated (primary schedule x2 doses of AstraZeneca plus a booster of Pfizer), >70-year-old woman with a history of lymphoma and hypertension who presented a SAR
Externí odkaz:
https://doaj.org/article/a4563b67ede2463ca061c016f76e974e
Autor:
Safiatou T Coulibaly, Paola Rossolillo, Flore Winter, Franziska K Kretzschmar, Mélanie Brayé, Darren P Martin, Daniela Lener, Matteo Negroni
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140741 (2015)
Identifying enzymes that, once introduced in cancer cells, lead to an increased efficiency of treatment constitutes an important goal for biomedical applications. Using an original procedure whereby mutant genes are generated based on the use of cond
Externí odkaz:
https://doaj.org/article/0c616b95e1784a8a9b2a762226ffeaf8
Autor:
Thierry Candresse, Denis Filloux, Brejnev Muhire, Charlotte Julian, Serge Galzi, Guillaume Fort, Pauline Bernardo, Jean-Heindrich Daugrois, Emmanuel Fernandez, Darren P Martin, Arvind Varsani, Philippe Roumagnac
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102945 (2014)
Comprehensive inventories of plant viral diversity are essential for effective quarantine and sanitation efforts. The safety of regulated plant material exchanges presently relies heavily on techniques such as PCR or nucleic acid hybridisation, which
Externí odkaz:
https://doaj.org/article/fccea2c035c64b36a9ec88fd3be2c579
Autor:
Dionne N Shepherd, Benjamin Dugdale, Darren P Martin, Arvind Varsani, Francisco M Lakay, Marion E Bezuidenhout, Adérito L Monjane, Jennifer A Thomson, James Dale, Edward P Rybicki
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105932 (2014)
Maize streak virus (MSV), which causes maize streak disease (MSD), is the major viral pathogenic constraint on maize production in Africa. Type member of the Mastrevirus genus in the family Geminiviridae, MSV has a 2.7 kb, single-stranded circular DN
Externí odkaz:
https://doaj.org/article/a56edbccd06545369df91d37df69ab41
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100400 (2014)
Genetic recombination is a major contributor to the ongoing diversification of HIV. It is clearly apparent that across the HIV-genome there are defined recombination hot and cold spots which tend to co-localise both with genomic secondary structures
Externí odkaz:
https://doaj.org/article/4c76682d5458413a82ce5e8c4f055e38
Autor:
Cica Urbino, Serafin Gutiérrez, Anna Antolik, Nabila Bouazza, Juliette Doumayrou, Martine Granier, Darren P Martin, Michel Peterschmitt
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58375 (2013)
Tomato yellow leaf curl virus (TYLCV) is a highly damaging begomovirus native to the Middle East. TYLCV has recently spread worldwide, recombining with other begomoviruses. Recent analysis of mixed infections between TYLCV and Tomato leaf curl Comoro
Externí odkaz:
https://doaj.org/article/a38478aa66f445dc914102f0ad42cc6e