Zobrazeno 1 - 10
of 299
pro vyhledávání: '"Darren P, Martin"'
Autor:
Francis E. Agamah, Thomas H. A. Ederveen, Michelle Skelton, Darren P. Martin, Emile R. Chimusa, Peter A. C. ’t Hoen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
BackgroundCOVID-19 disease is characterized by a spectrum of disease phases (mild, moderate, and severe). Each disease phase is marked by changes in omics profiles with corresponding changes in the expression of features (biosignatures). However, int
Externí odkaz:
https://doaj.org/article/da6917fc083f4b01b143c354996d6281
Autor:
Wonderful T. Choga, Gobuiwang Khilly Kurusa (Gasenna), James Emmanuel San, Tidimalo Ookame, Irene Gobe, Mohammed Chand, Badisa Phafane, Kedumetse Seru, Patience Matshosi, Boitumelo Zuze, Nokuthula Ndlovu, Teko Matsuru, Dorcas Maruapula, Ontlametse T. Bareng, Kutlo Macheke, Lesego Kuate-Lere, Labapotswe Tlale, Onalethata Lesetedi, Modiri Tau, Mpaphi B. Mbulawa, Pamela Smith-Lawrence, Mogomotsi Matshaba, Roger Shapiro, Joseph Makhema, Darren P. Martin, Tulio de Oliveira, Richard J. Lessells, Shahin Lockman, Simani Gaseitsiwe, Sikhulile Moyo
Publikováno v:
International Journal of Infectious Diseases, Vol 138, Iss , Pp 91-96 (2024)
We investigated intra-host genetic evolution using two SARS-CoV-2 isolates from a fully vaccinated (primary schedule x2 doses of AstraZeneca plus a booster of Pfizer), >70-year-old woman with a history of lymphoma and hypertension who presented a SAR
Externí odkaz:
https://doaj.org/article/a4563b67ede2463ca061c016f76e974e
Autor:
Joel O. Wertheim, Jade C. Wang, Mindy Leelawong, Darren P. Martin, Jennifer L. Havens, Moinuddin A. Chowdhury, Jonathan E. Pekar, Helly Amin, Anthony Arroyo, Gordon A. Awandare, Hoi Yan Chow, Edimarlyn Gonzalez, Elizabeth Luoma, Collins M. Morang’a, Anton Nekrutenko, Stephen D. Shank, Stefan Silver, Peter K. Quashie, Jennifer L. Rakeman, Victoria Ruiz, Lucia V. Torian, Tetyana I. Vasylyeva, Sergei L. Kosakovsky Pond, Scott Hughes
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors characterize a case of SARS-CoV-2 superinfection with Alpha and Epsilon variants, in which, via full genome sequencing analyses, they identify recombinant haplotypes in the spike, nucleocapsid, and ORF 8 coding regions, suggesting r
Externí odkaz:
https://doaj.org/article/c258b0e47c8e46188ea0732ebd024c24
Publikováno v:
Journal of Bioresources and Bioproducts, Vol 7, Iss 2, Pp 99-108 (2022)
Cellulose nanocrystal (CNC) with distinctive shape-morphology, enhanced thermal stability and dispersibility is essential for overcoming the challenges in processing polymer/CNC nanocomposites through melt compounding at elevated temperatures. This s
Externí odkaz:
https://doaj.org/article/0e0036de532647c38dec566e48f632e2
Autor:
Cathrine Scheepers, Josie Everatt, Daniel G. Amoako, Houriiyah Tegally, Constantinos Kurt Wibmer, Anele Mnguni, Arshad Ismail, Boitshoko Mahlangu, Bronwen E. Lambson, Darren P. Martin, Eduan Wilkinson, James Emmanuel San, Jennifer Giandhari, Nelia Manamela, Noxolo Ntuli, Prudence Kgagudi, Sandile Cele, Simone I. Richardson, Sureshnee Pillay, Thabo Mohale, Upasana Ramphal, Yeshnee Naidoo, Zamantungwa T. Khumalo, Gaurav Kwatra, Glenda Gray, Linda-Gail Bekker, Shabir A. Madhi, Vicky Baillie, Wesley C. Van Voorhis, Florette K. Treurnicht, Marietjie Venter, Koleka Mlisana, Nicole Wolter, Alex Sigal, Carolyn Williamson, Nei-yuan Hsiao, Nokukhanya Msomi, Tongai Maponga, Wolfgang Preiser, Zinhle Makatini, Richard Lessells, Penny L. Moore, Tulio de Oliveira, Anne von Gottberg, Jinal N. Bhiman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The SARS-CoV-2 PANGO lineage C.1.2 has been under monitoring by global health authorities as it has spread worldwide. Here, Bhiman and colleagues characterise the emergence of the lineage, and its neutralisation sensitivity using data from vaccinees
Externí odkaz:
https://doaj.org/article/e365317a28774fd29c4b6a0f6a77a17a
Autor:
Jordan Pennells, Darren J. Martin
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
With the rise of biomass-based materials such as nanocellulose, there is a growing need to develop statistical methods capable of leveraging inter-dependent experimental data to improve material design, product development, and process optimisation.
Externí odkaz:
https://doaj.org/article/7c712b4bc2c048a2bc06d7ab821728ef
Autor:
Steven A. Kemp, Oscar J. Charles, Anne Derache, Werner Smidt, Darren P. Martin, Collins Iwuji, John Adamson, Katya Govender, Tulio de Oliveira, Francois Dabis, Deenan Pillay, Richard A. Goldstein, Ravindra K. Gupta
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Prolonged virologic failure on 2nd-line protease inhibitor (PI)-based antiretroviral therapy (ART) without emergence of major protease mutations is well recognized and provides an opportunity to study within-host evolution in long-term virem
Externí odkaz:
https://doaj.org/article/d477d08fef62413e9573265028ca4d44
Autor:
Rana Arslan Afzal, Jordan Pennells, Yusuke Yamauchi, Pratheep K. Annamalai, Ashok Kumar Nanjundan, Darren J. Martin
Publikováno v:
Carbon Trends, Vol 7, Iss , Pp 100168- (2022)
Agricultural by-products offer attractive renewable feedstock options for the production of carbon to be used as electrode materials for energy storage applications. Developing insights into the carbonisation behaviour of these alternative feedstocks
Externí odkaz:
https://doaj.org/article/692858eed2d544a8a533d72094121cb2
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Musalula Sinkala et al. report that collectively, specific mutations of genes in 5 MAPK pathways are associated with worse patient survival. They identify gene components that are pharmacologically vulnerable to pathway inhibitors in cancer cell mode
Externí odkaz:
https://doaj.org/article/65ed10c9796044daa32dcf559a6c3a18
Autor:
Alexander G Lucaci, Jordan D Zehr, Stephen D Shank, Dave Bouvier, Alexander Ostrovsky, Han Mei, Anton Nekrutenko, Darren P Martin, Sergei L Kosakovsky Pond
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0275623 (2022)
An important unmet need revealed by the COVID-19 pandemic is the near-real-time identification of potentially fitness-altering mutations within rapidly growing SARS-CoV-2 lineages. Although powerful molecular sequence analysis methods are available t
Externí odkaz:
https://doaj.org/article/bca1a56d05294988afd66598cded39bb