Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Darren McAffee"'
Autor:
Deepti Karandur, Moitrayee Bhattacharyya, Zijie Xia, Young Kwang Lee, Serena Muratcioglu, Darren McAffee, Ethan D McSpadden, Baiyu Qiu, Jay T Groves, Evan R Williams, John Kuriyan
Publikováno v:
eLife, Vol 9 (2020)
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is an oligomeric enzyme with crucial roles in neuronal signaling and cardiac function. Previously, we showed that activation of CaMKII triggers the exchange of subunits between holoenzymes, potenti
Externí odkaz:
https://doaj.org/article/811a46346e94491a8a20e6b13f51505a
Publikováno v:
Proc Natl Acad Sci U S A
T cells exhibit remarkable sensitivity and selectivity in detecting and responding to agonist peptides (p) bound to MHC molecules in a sea of self pMHC molecules. Despite much work, understanding of the underlying mechanisms of distinguishing such li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b431c8ddc090ad7ab1f6c8bb1f1c594
https://doi.org/10.1073/pnas.2008303117
https://doi.org/10.1073/pnas.2008303117
Publikováno v:
Biophysical Journal
Under physiological conditions, peptide-MHC (pMHC) molecules can trigger T-cell receptors (TCRs) as monovalent ligands that are sparsely distributed on the plasma membrane of an antigen-presenting cell. TCR can also be activated by artificial cluster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb580b1796f1288485a2a3d632647f9b
https://pubmed.ncbi.nlm.nih.gov/34742402
https://pubmed.ncbi.nlm.nih.gov/34742402
Autor:
Darren McAffee, Evan R. Williams, Zijie Xia, Deepti Karandur, Jay T. Groves, Serena Muratcioglu, John Kuriyan, Moitrayee Bhattacharyya, Ethan D McSpadden, Young Kwang Lee, Baiyu Qiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c845cdc6808b475231e467f1df0dc2ee
https://doi.org/10.7554/elife.57784.sa2
https://doi.org/10.7554/elife.57784.sa2
Autor:
Evan R. Williams, Serena Muratcioglu, Baiyu Qiu, John Kuriyan, Young Kwang Lee, Jay T. Groves, Zijie Xia, Moitrayee Bhattacharyya, Darren McAffee, Deepti Karandur, Ethan D McSpadden
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Ca2+/calmodulin-dependent protein kinase II (CaMKII) is an oligomeric enzyme with crucial roles in neuronal signaling and cardiac function. Previously, we showed that activation of CaMKII triggers the exchange of subunits between holoenzymes, potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d16b134fb8dbc0c6101b4a32b14964
https://doi.org/10.1101/2020.04.15.043067
https://doi.org/10.1101/2020.04.15.043067
Publikováno v:
Biophysical Journal. 120:329a-330a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89126ea278ad58ce299109a5d32f7f0e
https://doi.org/10.1016/j.bpj.2020.11.2074
https://doi.org/10.1016/j.bpj.2020.11.2074
Autor:
Jay T. Groves, Scott D. Hansen, Jenny J. Lin, Darren McAffee, Steven Alvarez, Shalini T. Low-Nam
Publikováno v:
Biophysical Journal. 118:247a-248a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc3f5dfc02a1edf30bfdefc783f60be
https://doi.org/10.1016/j.bpj.2019.11.1450
https://doi.org/10.1016/j.bpj.2019.11.1450
Publikováno v:
Biophysical Journal. 120:330a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd0ea4a7c1de18aed16efe5793a67c45
https://doi.org/10.1016/j.bpj.2020.11.2076
https://doi.org/10.1016/j.bpj.2020.11.2076
Publikováno v:
Biophysical Journal. 118:245a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f808b521f6da8023870c6f729381ae23
https://doi.org/10.1016/j.bpj.2019.11.1436
https://doi.org/10.1016/j.bpj.2019.11.1436
Publikováno v:
Biophysical Journal. 118:203a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593fa46b2e85466a90dc819f59822278
https://doi.org/10.1016/j.bpj.2019.11.1221
https://doi.org/10.1016/j.bpj.2019.11.1221