Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Darren M. Riddy"'
Autor:
Maiju K. Rinne, Lauri Urvas, Ilona Mandrika, Dāvids Fridmanis, Darren M. Riddy, Christopher J. Langmead, Jyrki P. Kukkonen, Henri Xhaard
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Tunicates are evolutionary model organisms bridging the gap between vertebrates and invertebrates. A genomic sequence in Ciona intestinalis (CiOX) shows high similarity to vertebrate orexin receptors and protostome allatotropin receptors (AT
Externí odkaz:
https://doaj.org/article/3532f53292dc43e187ca5d3298309620
Autor:
Jean-Francois Gautier, Nicolas Venteclef, Assam El-Osta, Andrew J Murphy, Darren M Riddy, Helene L Kammoun, Sanja Bosnyak-Gladovic, Rocio De la Fuente Gonzalez, Jon Merlin, Mark Ziemann, Stewart Fabb, Tracie L Pierce, Natalie Diepenhorst, Patricia Rueda, William N Charman, Arthur Christopoulos, Patrick M Sexton, Roger J Summers, Mark A Febbraio, Philippe Delerive, Christopher J Langmead
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/4720f931b7654da0bb23e3c27d888fd0
Autor:
Jon Merlin, Julia Park, Teresa H. Vandekolk, Stewart A. Fabb, Jeanne Allinne, Roger J. Summers, Christopher J. Langmead, Darren M. Riddy
Publikováno v:
Molecular Pharmacology. 101:246-256
Specialized proresolving mediators (SPMs) and their cognate G protein-coupled receptors are implicated in autoimmune disorders, including chronic inflammation, rheumatoid arthritis, systemic scleroderma, and lupus erythematosus. To date, six G protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c08cd0bcd602496d84d926505e97ea72
https://doi.org/10.1124/molpharm.121.000422
https://doi.org/10.1124/molpharm.121.000422
Autor:
Darren M Riddy, Emily Goy, Philippe Delerive, Roger J Summers, Patrick M Sexton, Christopher J Langmead
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197177 (2018)
Monocyte-like cell lines (MCLCs), including THP-1, HL-60 and U-937 cells, are used routinely as surrogates for isolated human peripheral blood mononuclear cells (PBMCs). To systematically evaluate these immortalised cells and PBMCs as model systems t
Externí odkaz:
https://doaj.org/article/06eea1bb862d4727bf7f9a4135f38567
Autor:
Leigh C, Walker, Alice E, Berizzi, Nicola A, Chen, Patricia, Rueda, Victoria M, Perreau, Katherine, Huckstep, Jirawoot, Srisontiyakul, Piyarat, Govitrapong, Jia, Xiaojian, Craig W, Lindsley, Carrie K, Jones, Darren M, Riddy, Arthur, Christopoulos, Christopher J, Langmead, Andrew J, Lawrence
Publikováno v:
Biological psychiatry. 88(12)
Alcohol use disorder (AUD) is a major socioeconomic burden on society, and current pharmacotherapeutic treatment options are inadequate. Aberrant alcohol use and seeking alters frontostriatal function.We performed genome-wide RNA sequencing and subse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3ddfab81efe24c77df065e992c3f4a2
https://pubmed.ncbi.nlm.nih.gov/33213700
https://pubmed.ncbi.nlm.nih.gov/33213700
Autor:
Darren M, Riddy, Anna E, Cook, David M, Shackleford, Tracie L, Pierce, Elisabeth, Mocaer, Clotilde, Mannoury la Cour, Aurore, Sors, William N, Charman, Roger J, Summers, Patrick M, Sexton, Arthur, Christopoulos, Christopher J, Langmead
Publikováno v:
Neuropharmacology. 144
The histamine H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4e94add9aac8ddd3ecd01b903421d807
https://pubmed.ncbi.nlm.nih.gov/30359639
https://pubmed.ncbi.nlm.nih.gov/30359639
Autor:
David A, Sykes, Darren M, Riddy, Craig, Stamp, Michelle E, Bradley, Neil, McGuiness, Afrah, Sattikar, Danilo, Guerini, Ines, Rodrigues, Albrecht, Glaenzel, Mark R, Dowling, Florian, Mullershausen, Steven J, Charlton
Publikováno v:
British journal of pharmacology. 171(21)
The molecular mechanism underlying the clinical efficacy of FTY720-P is thought to involve persistent internalization and enhanced degradation of the S1P1 receptor subtype (S1P1R). We have investigated whether receptor binding kinetics and β-arresti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8242a0923714a73fea557d6fb0ed1101
https://pubmed.ncbi.nlm.nih.gov/24641481
https://pubmed.ncbi.nlm.nih.gov/24641481