Zobrazeno 1 - 10
of 426
pro vyhledávání: '"Darren M. Ashcroft"'
Publikováno v:
Diagnostic and Prognostic Research, Vol 8, Iss 1, Pp 1-8 (2024)
Abstract Background An increasing number of people are using multiple medications each day, named polypharmacy. This is driven by an ageing population, increasing multimorbidity, and single disease-focussed guidelines. Medications carry obvious benef
Externí odkaz:
https://doaj.org/article/14ad614658f04796ac0b34795e23f301
Autor:
Xiaomin Zhong, Victoria Palin, Darren M. Ashcroft, Ben Goldacre, Brian MacKenna, Amir Mehrkar, Sebastian C. J. Bacon, Jon Massey, Peter Inglesby, the OpenSAFELY collaborative, Kieran Hand, Alexander Pate, Tjeerd Pieter van Staa
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background With the global challenge of antimicrobial resistance intensified during the COVID-19 pandemic, evaluating adverse events (AEs) post-antibiotic treatment for common infections is crucial. This study aims to examines the changes in
Externí odkaz:
https://doaj.org/article/d2de836dfd2942c48582c4365c43915b
Autor:
Jane Ferguson, Gemma Stringer, Kieran Walshe, Ailsa Donnelly, Christos Grigoroglou, Thomas Allen, Evangelos Kontopantelis, Darren M. Ashcroft
Publikováno v:
Health Expectations, Vol 27, Iss 4, Pp n/a-n/a (2024)
ABSTRACT Introduction There have been some concerns about the impact of temporary doctors, otherwise known as locums, on patient safety and the quality of care. Despite these concerns, research has paid little attention to the implications of locum w
Externí odkaz:
https://doaj.org/article/42b528ffb4f9401d9680750ff2f630ef
Autor:
Bilal Bashir, Jonathan Schofield, Paul Downie, Michael France, Darren M. Ashcroft, Alison K. Wright, Stefano Romeo, Ioanna Gouni-Berthold, Akhlaq Maan, Paul N. Durrington, Handrean Soran
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
AimsHistorically, atherosclerotic cardiovascular disease (ASCVD) risk profile mitigation has had a predominant focus on low density lipoprotein cholesterol (LDL-C). In this narrative review we explore the residual ASCVD risk profile beyond LDL-C with
Externí odkaz:
https://doaj.org/article/c848dfd6eaa84944b4170ee1460c2040
Autor:
Christos Grigoroglou, Kieran Walshe, Evangelos Kontopantelis, Jane Ferguson, Gemma Stringer, Darren M. Ashcroft, Thomas Allen
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Temporary doctors, known as locums, are a key component of the medical workforce in the NHS but evidence on differences in quality and safety between locum and permanent doctors is limited. We aimed to examine differences in the c
Externí odkaz:
https://doaj.org/article/73905478f15148c0a794f3365495787f
Autor:
Katherine Payne, Federica Ciamponi, Thomas Allen, Alex J. Thompson, Georgios Gkountouras, Sean P. Gavan, Claire T. Reid, Christopher E. M. Griffiths, Darren M. Ashcroft
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 1, Pp 117-127 (2024)
Abstract Background People with psoriasis live with other long‐term conditions (co‐morbidities) that affect their use of healthcare, but the scale of this is not well characterised. Objectives Estimate the concurrent prevalence of co‐morbiditie
Externí odkaz:
https://doaj.org/article/968ecb95879a465382dd0963568e4789
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Long-term opioid use is associated with dependency, addiction, and serious adverse events. Although a framework to reduce inappropriate opioid prescribing exists, there is no consensus on prescribing indicators for preventable opi
Externí odkaz:
https://doaj.org/article/1793badc550048fc9e07a82a4b2f0130
Autor:
Artitaya Lophatananon, Matthew Carr, Brian Mcmillan, Curtis Dobson, Ruth Itzhaki, Rosa Parisi, Darren M. Ashcroft, Kenneth R. Muir
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Dementia affects ability to remember, think, or make decisions that interfere with doing everyday activities. There is no cure, therefore any prevention or delay of the onset is of importance. This study aims to investigate the as
Externí odkaz:
https://doaj.org/article/16b276f79589496b8f222dcf95831e28
Autor:
Eleni Domzaridou, Tjeerd Van Staa, Andrew G. Renehan, Natalie Cook, William Welfare, Darren M. Ashcroft, Victoria Palin
Publikováno v:
Current Oncology, Vol 30, Iss 9, Pp 8434-8443 (2023)
Background: There is limited evidence in humans as to whether antibiotics impact the effectiveness of cancer treatments. Rodent studies have shown that disruption in gut microbiota due to antibiotics decreases cancer therapy effectiveness. We evaluat
Externí odkaz:
https://doaj.org/article/170dc217fa86448aae637be8d15ee981
Autor:
Ya-Ting Yang, Xiaomin Zhong, Ali Fahmi, Simon Watts, Darren M. Ashcroft, Jon Massey, Louis Fisher, Brian MacKenna, Amir Mehrkar, Sebastian C. J. Bacon, Ben Goldacre, Kieran Hand, Tjeerd van Staa, Victoria Palin
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-18 (2023)
Abstract Background There is concern that the COVID-19 pandemic altered the management of common infections in primary care. This study aimed to evaluate infection-coded consultation rates and antibiotic use during the pandemic and how any change may
Externí odkaz:
https://doaj.org/article/a8db20df2fb5467d8ed9caa425eaed98