Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Darren K. Hannesson"'
Autor:
Michael E. Corcoran, Amy E. Wallace, Darren K. Hannesson, Paul Mohapel, Michael S Pollock, John G. Howland
Publikováno v:
Epilepsy & Behavior. 13:52-61
Kindling in rats produces enduring behavioral changes that parallel the psychobehavioral disturbances frequently accompanying temporal lobe epilepsy. Some evidence suggests that the site of kindling is an important determinant of the type of behavior
Publikováno v:
Hippocampus. 18:251-257
The hippocampus is critical for spatial memory. Recently, subregional differences in the function of hippocampus have been described in a number of behavioral tasks. The present experiments assessed the effects of reversibly lesioning either the dors
Publikováno v:
Behavioural Brain Research. 177:30-36
The neural mechanisms mediating prepulse inhibition (PPI) appear to have relevance to neurological and psychiatric disorders. Patients with temporal lobe epilepsy exhibit psychotic symptoms and disrupted PPI, therefore the present experiments examine
Autor:
Michael E. Corcoran, Darren K. Hannesson, Michael S Pollock, Paul Mohapel, John G. Howland, A E Wallace
Publikováno v:
European Journal of Neuroscience. 21:1081-1090
Temporal lobe epilepsy (TLE) is frequently accompanied by memory impairments and, although their bases are unknown, most research has focused on the hippocampus. The present study investigated the importance of another medial temporal lobe structure,
Publikováno v:
European Journal of Neuroscience. 20:2639-2648
Abnormal activity in corticolimbic circuits during development may be a predisposing factor for schizophrenia. Permanent or temporary lesions of limbic structures such as the ventral hippocampus and basolateral amygdala in rats on postnatal day (PND)
Publikováno v:
Behavioural Brain Research. 153:273-285
The present study describes two novel tasks relying on spontaneous patterns of exploration in a radial-arm maze that can be used to assess spatial recognition memory and spatial temporal order memory (i.e. memory for the order in which places have be
Publikováno v:
The Journal of Neuroscience. 24:4596-4604
The present study investigated the roles of the perirhinal cortex, medial prefrontal cortex, and intrahemispheric interactions between them in recognition and temporal order memory for objects. Experiment 1 assessed the effects of bilateral microinfu
Publikováno v:
Epilepsy Research. 58:145-154
Dorsal hippocampal kindling impairs subsequent performance on spatial tasks. The relation between this effect and the extent of kindling achieved prior to testing has not been clearly established. Thus, the present study investigated the effects of d
Autor:
Larry C. Schmued, Amy E. Wallace, Deborah M. Saucier, Shu-Sen Cui, William G. Honer, Xia Zhang, Michael E. Corcoran, Darren K. Hannesson
Publikováno v:
The Journal of Neuroscience. 22:6052-6061
Temporal lobe epilepsy, the most common type of epilepsy in adult humans, is characterized clinically by the progressive development of spontaneous recurrent seizures of temporal lobe origin and pathologically by hippocampal neuronal loss and mossy f
Autor:
Michael E. Corcoran, Darren K. Hannesson, Xia Zhang, John G. Howland, Deborah M. Saucier, Amy E. Wallace
Publikováno v:
The Journal of Neuroscience. 21:3674-3687
The claustrum has been implicated in the kindling of generalized seizures from limbic sites. We examined the susceptibility of the anterior claustrum itself to kindling and correlated this with an anatomical investigation of its afferent and efferent