Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Darren J, Cook"'
Publikováno v:
Advances in protein chemistry and structural biology. 122
Cytochromes P450 (P450s) are a large superfamily of heme-containing monooxygenases. P450s are found in all Kingdoms of life and exhibit incredible diversity, both at sequence level and also on a biochemical basis. In the majority of cases, P450s can
Publikováno v:
Advances in Protein Chemistry and Structural Biology ISBN: 9780128177624
Cytochromes P450 (P450s) are a large superfamily of heme-containing monooxygenases. P450s are found in all Kingdoms of life and exhibit incredible diversity, both at sequence level and also on a biochemical basis. In the majority of cases, P450s can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519e657b93227f5812c467d4a0b2c929
https://doi.org/10.1016/bs.apcsb.2020.06.005
https://doi.org/10.1016/bs.apcsb.2020.06.005
Autor:
James R. Marshall, Darren J. Cook, Peiyuan Yao, Nicholas J. Turner, Kirsty M. Graham, Richard A. M. Duncan, Juan Mangas-Sanchez, Simon J. Charnock, Sarah L. Montgomery, Rachel S. Heath, Ryan B. Palmer, Thomas W. Thorpe, James Finnigan
Publikováno v:
Nat Chem
Nature Chemistry
Marshall, J R, Yao, P, Montgomery, S L, Finnigan, J D, Thorpe, T W, Palmer, R B, Mangas-sanchez, J, Duncan, R A M, Heath, R S, Graham, K M, Cook, D J, Charnock, S J & Turner, N J 2020, ' Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination ', Nature Chemistry, vol. 13, no. 2, 0, pp. 140-148 . https://doi.org/10.1038/s41557-020-00606-w
Nature Chemistry
Marshall, J R, Yao, P, Montgomery, S L, Finnigan, J D, Thorpe, T W, Palmer, R B, Mangas-sanchez, J, Duncan, R A M, Heath, R S, Graham, K M, Cook, D J, Charnock, S J & Turner, N J 2020, ' Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination ', Nature Chemistry, vol. 13, no. 2, 0, pp. 140-148 . https://doi.org/10.1038/s41557-020-00606-w
Finding faster and simpler ways to screen protein sequence space to enable the identification of new biocatalysts for asymmetric synthesis remains both a challenge and a rate-limiting step in enzyme discovery. Biocatalytic strategies for the synthesi
Cytochromes P450, a family of heme-containing monooxygenases that catalyze a diverse range of oxidative reactions, are so-called due to their maximum absorbance at 450nm, ie, "Pigment-450nm," when bound to carbon monoxide. They have appeal both acade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e9c764dabc62aec2a250e9f3949eeb8
https://doi.org/10.1016/bs.apcsb.2016.07.003
https://doi.org/10.1016/bs.apcsb.2016.07.003
Autor:
David J. Williams, and Andrew J. P. White, Anthony F. Hill, Darren J. Cook, Stephen Anderson, John M. Malget
Publikováno v:
Organometallics. 23:2552-2557
The reaction of [W(⋮CR)(CO)2(η-C5H5)] (R = C6H3Me2-2,6) with thionyl chloride provides the metallacyclic alkylidene complex [W(CRSCRS)Cl3(η-C5H5)], while similar treatment of [W(⋮CR)(CO)2{HB(pz)3}]...
Autor:
Anthony F. Hill, Darren J. Cook
Publikováno v:
Organometallics. 22:3502-3512
Synthetic routes to a range of thioaroyl complexes of tungsten and molybdenum are reported. Successive treatment of [M(CO)6] (M = Mo, W) with LiC6H4OMe-4·LiBr, (CF3CO)2O, and 2,2-bipyridyl (bipy) p...
Publikováno v:
Organometallics. 20:2468-2476
Synthetic routes to thiocarbamoyl (thiocarboxamide) complexes of divalent molybdenum and tungsten are reported: The reaction of fac-[Mo(CO)3(NCMe)3] with N,N-dimethyl thiocarbamoyl chloride (Me2NC(S)Cl) at low temperature provides a thermally labile
Autor:
Andrew J. P. White, Karsten J. Harlow, Darren J. Cook, Beatrice Buriez, Tom Welton, David J. Williams, Anthony F. Hill, James D. E. T. Wilton-Ely
Publikováno v:
Journal of Organometallic Chemistry. 578:264-267
The reaction of [RuCl(PPh3)2{HB(pz)3}] (pz=pyrazol-1-yl) with 4-ethynyl toluene provides [RuCl(CCHC6H4Me-4)(PPh3){HB(pz)3}] (1a) which reacts with [Et2NH2][S2CNEt2] to give the metallacyclic alkenyl complex [Ru{C(CHC6H4Me-4)SC(NEt2)S}(PPh3){
Publikováno v:
Journal of the Chemical Society, Dalton Transactions. :1171-1174
The reaction of bis(alkynyl)mercurials [Hg(CCR)2] (R = C6H5, C6H4Me-4 or ferrocenyl) with diaryl dichalcogenides (ER′)2 (E = Se, R′ = C6H5 or C6H4Cl-4; E = Te, R′ = C6H5) conveniently provided high yields of the alkynyl aryl chalcogenoethers RC
Autor:
Karsten J. Harlow, David J. Williams, Darren J. Cook, Anthony F. Hill, Tom Welton, Andrew J. P. White
Publikováno v:
New Journal of Chemistry. 22:311-314
The reaction of [Ru(â–·CC6H4OMe-4)Cl(CO)(PPh3)2] with [NH4][S2CNC4H8] provides the structurally characterised metallacycle [Ru{κ2-CH(C6H4OMe-4)SC(NC4H8)S}(S2CNC4H8)(CO)(PPh3)], related examples of which arise from the reactions of xanthate or di