Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Darren Creek"'
Autor:
Yu-Wei Lin, Mei-Ling Han, Jinxin Zhao, Yan Zhu, Gauri Rao, Alan Forrest, Jiangning Song, Keith S. Kaye, Paul Hertzog, Anthony Purcell, Darren Creek, Qi Tony Zhou, Tony Velkov, Jian Li
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Polymyxins are used as a last-resort class of antibiotics against multidrug-resistant (MDR) Gram-negative Pseudomonas aeruginosa. As polymyxin monotherapy is associated with potential development of resistance, combination therapy is highly recommend
Externí odkaz:
https://doaj.org/article/6071f506d274405ab08bb2a15335c8e8
Autor:
Isabel M Vincent, Darren Creek, David G Watson, Mohammed A Kamleh, Debra J Woods, Pui Ee Wong, Richard J S Burchmore, Michael P Barrett
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001204 (2010)
Human African trypanosomiasis, endemic to sub-Saharan Africa, is invariably fatal if untreated. Its causative agent is the protozoan parasite Trypanosoma brucei. Eflornithine is used as a first line treatment for human African trypanosomiasis, but th
Externí odkaz:
https://doaj.org/article/8f3e95995c734e62a7d35c0a2ca33da7
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance. 20:135-144
New antimalarial compounds with novel mechanisms of action are urgently needed to combat the recent rise in antimalarial drug resistance. Phenotypic high-throughput screens have proven to be a successful method for identifying new compounds, however,
Autor:
Liang Xie, Dakota Rhys-Jones, Rikeish R. Muralitharan, Evany Dinakis, Michael Nakai, Madeleine Paterson, Alex Peh, Hamdi Jama, Ekaterina Salimova, Dovile Anderson, Caroline Ang, Md Jahangir Alam, Yu-Anne Yap, Darren Creek, Remy Robert, CK Yao, Daniel So, Geoffrey A. Head, Peter R. Gibson, Jane Muir, Joanne A. O’Donnell, Charles R. Mackay, Francine Z. Marques
Dietary fibre regulates blood pressure (BP) through gut microbial production of acidic metabolites known as short-chain fatty acids (SCFAs). The specific mechanisms of how SCFAs regulate BP are still emerging. We hypothesised that acidic metabolites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6313dd096abf10c0181991c506dc778
https://doi.org/10.1101/2022.11.17.516695
https://doi.org/10.1101/2022.11.17.516695
Autor:
Joanne O'Donnell, Christopher K. Barlow, Charles R. Mackay, Maria Kaparakis-Liaskos, Rikeish R. Muralitharan, Michael E Nakai, Evany Dinakis, Chudan Xu, Madeleine Paterson, Ekaterina Salimova, Natalie J. Bitto, Francine Z Marques, Darren Creek, Hamdi A. Jama, Liang Xie
Publikováno v:
Hypertension. 78
High dietary fibre is fermented by the gut microbiota, resulting in the release of metabolites called short-chain fatty acids (SCFAs). Both fibre and SCFAs can reduce high blood pressure (BP) and its associated cardio-renal complications. However, th
Autor:
David M. Kaye, Christopher K. Barlow, Geoffrey A. Head, Khoury Gabriela, Francine Z Marques, Hamdi A. Jama, Stephanie Yiallourou, Evany Dinakis, Kirill Tsyganov, Rikeish R. Muralitharan, Michael E Nakai, Darren Creek, Melinda Carrington, Chudan Xu
Publikováno v:
Hypertension. 76
Low fermentable fibre intake has emerged as an important risk factor for hypertension through changes in the gut microbiota, but the biological pathways and specific metabolites involved are unknown. We performed untargeted liquid-chromatography mass
Publikováno v:
Rapid communications in mass spectrometry : RCM. 25(22)
This work describes a novel application of capillary-flow ion chromatography mass spectrometry for metabolomic analysis, and comparison of the technique to octadecyl silica and hydrophilic interaction chromatography (HILIC)-based mass spectrometry. W
Autor:
Darren Creek
Publikováno v:
Dictionary of Bioinformatics and Computational Biology.
Autor:
Xiaofang Wang, Yuxiang Dong, Sergio Wittlin, Darren Creek, Jacques Chollet, Susan A. Charman, Josefina Santo Tomas, Christian Scheurer, Christopher Snyder, Jonathan L. Vennerstrom
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 23, p5840-5847, 8p
Publikováno v:
Monash University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::5a4b4d37ad686b684ecd946de64298ac
https://research.monash.edu/en/publications/2d652826-7012-4c7b-9f55-03e76f29766a
https://research.monash.edu/en/publications/2d652826-7012-4c7b-9f55-03e76f29766a