Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Darren Carpizo"'
Publikováno v:
Bio-Protocol, Vol 11, Iss 20 (2021)
In the cell, the thermodynamic stability of a protein – and hence its biological activity – can change dramatically as a result of perturbations in its amino acid sequence and the concentration of stabilizing ligands. This interplay is particular
Externí odkaz:
https://doaj.org/article/46ae8918e52140dea003d8e131e94ffa
Autor:
Anthony Spartan Casabianca, Ana Ivette Hernandez Caballero, Loralei L Thornburg, Darren Carpizo
Publikováno v:
BMJ case reports. 15(6)
Hepatic cavernous haemangioma is a benign tumour of vascular origin found within the liver. Often incidentally diagnosed, the management of these vascular masses is frequently determined by the size of the mass and symptoms associated with its compre
Autor:
Chris R. Harris, Crissy Dudgeon, Orjola Prela, Lan Wang, Anthony Casabianca, Juliana Cazarin de Menezes, Christina Davidson, Paula Vertino, Brian Altman, Darren Carpizo
Publikováno v:
Cancer Research. 83:1287-1287
Latent recurrence following curative-intent pancreatic cancer surgery is a major clinical problem thought to be due to the reactivation of dormant tumor cells that disseminate before the primary tumor has been removed. How dormancy is established and
Autor:
Chris R. Harris, Orjola Prela, Lan Wang, Anthony Casabianca, Wade Narrow, Zachary Sechrist, Tracy Withers, Cory Shields, Asra Asad, Aram Hezel, Darren Carpizo
Publikováno v:
Cancer Research. 83:1286-1286
The axonal guidance receptor UNC5B is considered to be a tumor suppressor because it promotes apoptosis in the absence of its protein ligand, NTN1. But we find that UNC5B is not a tumor suppressor of pancreatic ductal adenocarcinomas (PDAC), and inst
Autor:
Chris Harris, Anthony Casabianca, Zach Sechrist, Cory Shields, Wade Narrow, Tracy Withers, Crissy Dudgeon, Mike O'Dell, Aram Hezel, Darren Carpizo
Publikováno v:
Cancer Research. 82:B021-B021
Axon guidance pathways have often been linked to tumorigenesis by informatics analyses, but their roles in tumorigenesis are not well understood at a functional level. Here we show that axon guidance receptor UNC5B and its ligand, NTN1, promote the m
Autor:
Crissy Dudgeon, Anthony Casabianca, Chris Harris, Igor Astsaturov, Charline Ogier, Xiaoyang Su, Jason Pitarresi, Wade Narrow, Fady Soliman, Tracy Withers, Patrick Mehlen, Darren Carpizo
Publikováno v:
Cancer Research. 82:B020-B020
A hallmark of pancreatic ductal adenocarcinoma (PDAC) is its proclivity for metastasis as evidenced by the fact that 85% are stage IV at diagnosis. This highlights the need to better understand the biology of metastatic PDAC and identify novel therap
Autor:
Tamas A. Gonda, James Farrell, Michael Wallace, Lauren Khanna, Eileen Janec, Richard Kwon, Michael Saunders, Uzma D. Siddiqui, Randall Brand, Diane M. Simeone, Laufey Amundadottir, Georg Beyer, Yan Bi, Teresa Brentnall, Darren Carpizo, Alfredo Carrato, Hersh Chandarana, Jennifer Chun, Daniel Chung, Beth Dudley, Julia Earl, Jessica Everett, Melissa Fava, Srinivas Gaddam, Steve Gallinger, Talia Golan, John Graff, William Greenhalf, Aaron Grossberg, Philip Hart, Spring Holter, Chenchan Huang, Gregory Idos, Priyanka Kanth, Fay Kastrinos, Bryson Katona, Vivek Kaul, Kelsey Klute, Sonia Kupfer, Joy Liau, James Lin, James Lindberg, Andrew Lowy, Aimee Lucas, Julia Mayerle, Nipun Merchant, Salvatore Paiella, Jennifer Permuth, Intan Schrader, Rosalie Sears, Jens Siveke, Daniel Sussman, George Zogopoulos
Publikováno v:
Gastrointestinal endoscopy. 95(4)
Background and Aims Pancreatic ductal adenocarcinoma is an aggressive disease most often diagnosed after local progression or metastatic dissemination, precluding resection and resulting in a high mortality rate. For individuals with elevated persona
Autor:
Tamas A. Gonda, Jessica N. Everett, Michael Wallace, Diane M. Simeone, Laufey Amundadottir, Georg Beyer, Yan Bi, Teresa Brentnall, Darren Carpizo, Alfredo Carrato, Hersh Chandarana, Jennifer Chun, Daniel Chung, Beth Dudley, Julia Earl, Melissa Fava, Srinivas Gaddam, Steve Gallinger, Talia Golan, John Graff, William Greenhalf, Aaron Grossberg, Philip Hart, Spring Holter, Chenchan Huang, Gregory Idos, Priyanka Kanth, Fay Kastrinos, Bryson Katona, Vivek Kaul, Lauren Khanna, Kelsey Klute, Sonia Kupfer, Joy Liau, James Lin, James Lindberg, Andrew Lowy, Aimee Lucas, Julia Mayerle, Nipun Merchant, Salvatore Paiella, Jennifer Permuth, Intan Schrader, Rosalie Sears, Jens Siveke, null Daniel Sussman, George Zogopoulos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34908531b43859406e2b96cb72dea08e
https://hdl.handle.net/11562/1081890
https://hdl.handle.net/11562/1081890
Autor:
Karishma, Khullar, Nell Maloney, Patel, Cristan, Anderson, Anupama, Chundury, Darren, Carpizo, Daniel, Feingold, Miral, Grandhi, Howard, Hochster, Krupa, Jani, Timothy, Kennedy, Russell, Langan, Kristen, Spencer, David, August, Salma K, Jabbour
Publikováno v:
Oncol Hematol Rev
Locally advanced rectal cancer has broadly been defined as T3, T4, or lymph node-positive disease. In the 1990s, adjuvant chemoradiation was considered the optimal management for locally advanced rectal cancer. However, the paradigm shifted when the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::254770c4336cf2420f330eacd9f2591a
https://europepmc.org/articles/PMC7439775/
https://europepmc.org/articles/PMC7439775/
Publikováno v:
Cancer Research. 76:LB-351
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive human malignancies with a 5-year survival rate for all stages of only 6%. While surgery remains the most effective treatment for pancreatic cancer, the majority of patients that un