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of 4
pro vyhledávání: '"Darren B. McAffee"'
Autor:
Darren B. McAffee, Mark K. O’Dair, Jenny J. Lin, Shalini T. Low-Nam, Kiera B. Wilhelm, Sungi Kim, Shumpei Morita, Jay T. Groves
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The linker for activation of T cells (LAT) protein is involved in the activation of T cells. Here the authors discover micron scale LAT condensation events downstream of singly bound T-cell receptors during T cell activation and characterise how LAT
Externí odkaz:
https://doaj.org/article/82822abc182e454491b09902b4a15ff6
Autor:
Darren B. McAffee, Mark K. O’Dair, Jenny J. Lin, Shalini T. Low-Nam, Kiera B. Wilhelm, Sungi Kim, Shumpei Morita, Jay T. Groves
LAT assembly into a two-dimensional protein condensate is a prominent feature of antigen discrimination by T cells. Here, we use single-molecule imaging techniques to resolve the spatial position and temporal duration of each pMHC:TCR molecular bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200a2f90fa627c610edc935830b51b1b
https://doi.org/10.1101/2021.12.16.472676
https://doi.org/10.1101/2021.12.16.472676
Autor:
McAffee, Darren B., O'Dair, Mark K., Lin, Jenny J., Low-Nam, Shalini T., Wilhelm, Kiera B., Kim, Sungi, Morita, Shumpei, Groves, Jay T.
Publikováno v:
Nature Communications; 12/2/2022, Vol. 13 Issue 1, p1-18, 18p
Autor:
Lin, Jenny J. Y., Low-Nam, Shalini T., Alfieri, Katherine N., McAffee, Darren B., Fay, Nicole C., Groves, Jay T.
Publikováno v:
Science Signaling; 1/15/2019, Vol. 12 Issue 564, pN.PAG-N.PAG, 1p