Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Darren A. Blackburn"'
Autor:
Darren M. Blackburn, Korin Sahinyan, Aldo Hernández-Corchado, Felicia Lazure, Vincent Richard, Laura Raco, Gabrielle Perron, René P. Zahedi, Christoph H. Borchers, Christoph Lepper, Hiroshi Kawabe, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110241- (2024)
Summary: Adult stem cells play a critical role in tissue repair and maintenance. In tissues with slow turnover, including skeletal muscle, these cells are maintained in a mitotically quiescent state yet remain poised to re-enter the cell cycle to rep
Externí odkaz:
https://doaj.org/article/aed6cff8a4964cb88e74903bb70434c9
Autor:
Felicia Lazure, Rick Farouni, Korin Sahinyan, Darren M. Blackburn, Aldo Hernández-Corchado, Gabrielle Perron, Tianyuan Lu, Adrien Osakwe, Jiannis Ragoussis, Colin Crist, Theodore J. Perkins, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Aging leads to significant alteration in the gene expression of muscle stem cells. In vivo exposure of muscle stem cells from aged mice to a young niche environment restores the expression of a significant portion of age-altered genes in mice.
Externí odkaz:
https://doaj.org/article/e5288f7ec0dd4f6f85473190f3773765
Autor:
Korin Sahinyan, Darren M Blackburn, Marie-Michelle Simon, Felicia Lazure, Tony Kwan, Guillaume Bourque, Vahab D Soleimani
Publikováno v:
eLife, Vol 11 (2022)
Myofibers are the main components of skeletal muscle, which is the largest tissue in the body. Myofibers are highly adaptive and can be altered under different biological and disease conditions. Therefore, transcriptional and epigenetic studies on my
Externí odkaz:
https://doaj.org/article/42fc0b9135ae4f4885d62e564df82426
Autor:
Darren M. Blackburn, Korin Sahinyan, Aldo Hernández-Corchado, Felicia Lazure, Vincent Richard, Laura Raco, René P. Zahedi, Christoph H. Borchers, Christoph Lepper, Hiroshi Kawabe, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
SummaryAdult stem cells play a critical role in tissue repair and maintenance. In tissues with slow turnover, including skeletal muscle, these cells are maintained in a mitotically quiescent state yet remain poised to re-enter the cell cycle to reple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63ffe98257bcf1eb830b19b2c36233f9
https://doi.org/10.1101/2023.05.10.540205
https://doi.org/10.1101/2023.05.10.540205
Publikováno v:
The FEBS Journal. 290:1267-1289
Muscle stem cells (MuSCs) are required for life-long muscle regeneration. In general, aging has been linked to a decline in the numbers and the regenerative potential of MuSCs. Muscle regeneration depends on the proper functioning of MuSCs, which is
Autor:
Felicia Lazure, Aldo H. Corchado, Darren M. Blackburn, Theodore J. Perkins, Vahab D. Soleimani, Hamed S. Najafabadi
Publikováno v:
J Biol Chem
Skeletal muscle is a heterogeneous tissue. Individual myofibers that make up muscle tissue exhibit variation in their metabolic and contractile properties. Although biochemical and histological assays are available to study myofiber heterogeneity, ef
Autor:
Ioannis Ragoussis, Darren M. Blackburn, Hamed S. Najafabadi, Aldo Hernandez-Corchado, Theodore J. Perkins, Rick Farouni, Korin Sahinyan, Tianyuan Lu, Gabrielle Perron, Felicia Lazure, Colin Crist, Arezu Jahani-Asl, Vahab D. Soleimani
Adult stem cells are indispensable for tissue regeneration. Tissue-specific stem cells reside in a specialized location called their niche, where they are in constant cross talk with neighboring niche cells and circulatory signals from their environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fa502088b35cd990b1f2e69753039fa
https://doi.org/10.21203/rs.3.rs-622329/v1
https://doi.org/10.21203/rs.3.rs-622329/v1
Autor:
Marie-Michelle Simon, Darren M Blackburn, Korin Sahinyan, Felicia Lazure, Tony Kwan, Guillaume Bourque, Vahab D Soleimani
Publikováno v:
eLife. 11
Myofibers are the main components of skeletal muscle, which is the largest tissue in the body. Myofibers are highly adaptive and can be altered under different biological and disease conditions. Therefore, transcriptional and epigenetic studies on my
Autor:
Vahab D. Soleimani, Felicia Lazure, Darren M. Blackburn, Marie-Michelle Simon, Korin Sahinyan, Tony Kwan, Guillaume Bourque
Skeletal myofibers are the main components of skeletal muscle which is the largest tissue in the body. Myofibers are highly adaptive in nature and they can vary in different biological and disease conditions. Therefore, transcriptional and epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f88223bc0045840abe31e2d1221cc85
https://doi.org/10.1101/2021.06.14.448380
https://doi.org/10.1101/2021.06.14.448380