Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Darren, Veach"'
Autor:
Nayanendu Saha, Sang Gyu Lee, Eeva-Christine Brockmann, M. Jason de la Cruz, Yehuda Goldgur, Rachelle P. Mendoza, Elisa de Stanchina, Tanzy M. Love, Josh Marvald, Yan Xu, Kai Xu, Juha P. Himanen, Urpo Lamminmäki, Darren Veach, Dimitar B. Nikolov
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117605- (2024)
ADAM17 sheds EGFR/erbB ligands and triggers oncogenic pathways that lead to the progression of solid tumors. We targeted the ADAM17 disintegrin and cysteine rich domain region (D+C) to generate a panel of single-chain antibody fragments (scFvs) that
Externí odkaz:
https://doaj.org/article/84264756775b4efcb4e2b8cf8b67bcb8
Autor:
David Ulmert, Michael R. McDevitt, Steven M. Larson, Hans G. Lilja, Diane S. Abou, Jason S. Lewis, Sai Kiran Sharma, Sven-Erik Strand, Dipti Metha, Philip A. Watson, Darren Veach, Nicholas Mitsiades, Anson T. Ku, Daniel L.J. Thorek
Purpose:The impact of androgen receptor (AR) activity in breast cancer biology is unclear. We characterized and tested a novel therapy to an AR-governed target in breast cancer.Experimental Design: We evaluated the expression of prototypical AR gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0565406add7f006b2b6ba190eb688bfa
https://doi.org/10.1158/1078-0432.c.6528689.v1
https://doi.org/10.1158/1078-0432.c.6528689.v1
Autor:
David Ulmert, Michael R. McDevitt, Steven M. Larson, Hans G. Lilja, Diane S. Abou, Jason S. Lewis, Sai Kiran Sharma, Sven-Erik Strand, Dipti Metha, Philip A. Watson, Darren Veach, Nicholas Mitsiades, Anson T. Ku, Daniel L.J. Thorek
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e83aae332f72d9b9d755d44bec01f9c
https://doi.org/10.1158/1078-0432.22474103
https://doi.org/10.1158/1078-0432.22474103
Autor:
Darren Veach, Brett Vaughn, Daniela Burnes Vargas, Shin Seo, Blesida Punzalan, Hong Xu, Hong-fen Guo, Simone Krebs, Guangbin Yang, Ouathek Ouerfelli, Nai-Kong Cheung, Steven Larson, Sarah Cheal
Publikováno v:
Nuclear Medicine and Biology. :S61-S62
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d2d57cd66a22c0acd665402f32ff804
https://doi.org/10.1016/s0969-8051(22)00156-1
https://doi.org/10.1016/s0969-8051(22)00156-1
Autor:
Sebastian Chung, Christopher Chandler, Darren Veach, Michael McDevitt, Pat Zanzonico, Shin Seo, Blesida Punzalan, Daniela Burnes Vargas, Hong Xu, Hong-fen Guo, Ouathek Ouerfelli, Guangbin Yang, Andrea Cercek, Garrett Nash, Nai-Kong Cheung, Sarah Cheal, Steven Larson
Publikováno v:
Nuclear Medicine and Biology. :S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9a19cac7d6d7122f45bb8cda5ed2cd6
https://doi.org/10.1016/s0969-8051(22)00136-6
https://doi.org/10.1016/s0969-8051(22)00136-6
Autor:
Sebastian K. Chung, Christopher S. Chandler, Daniela Burnes Vargas, Shin H. Seo, Michael R. McDevitt, Darren Veach, Blesida Punzalan, Xu Hong, Hong-fen Guo, Garrett M. Nash, Andrea Cercek, Nai-Kong V. Cheung, Steven M. Larson, Sarah M. Cheal
Publikováno v:
Molecular Cancer Therapeutics. 20:P168-P168
Objectives Epithelial ovarian carcinoma (EOC) is a common and lethal gynecologic malignancy that frequently presents as advanced staged disease, such as peritoneal carcinomatosis (PC). We previously reported cures in BT-474 murine xenografts with Pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e63ccadc851df3544fd46f281f52cd9
https://doi.org/10.1158/1535-7163.targ-21-p168
https://doi.org/10.1158/1535-7163.targ-21-p168
Autor:
Darren Veach, Garrett M. Nash, Sebastian K. Chung, Hong-fen Guo, Blesida Punzalan, Christopher Chandler, Steven M. Larson, Shin Hyuk Seo, Brian H. Santich, Cheung Nai-Kong, Andrea Cercek, Mao Wang, Hong Xu, Sarah M. Cheal, Daniela Burnes Vargas
Publikováno v:
Cancer Research. 81:1391-1391
Objectives: There is increasing interest in the potential role of radioimmunotherapy in the treatment of peritoneal carcinomatosis (PC), locoregional metastasis throughout the peritoneal cavity. We recently described a SADA platform when applied to G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1934e2ef2255709b1c5e30b77f46b0c
https://doi.org/10.1158/1538-7445.am2021-1391
https://doi.org/10.1158/1538-7445.am2021-1391
Autor:
Robert Damoiseaux, Hans Lilja, Teja Kalidindi, Michael R. McDevitt, Sven-Erik Strand, Caius G. Radu, Darren Veach, Michael J. Morris, Mesude Bicak, Robert J. Klein, Katharina Lueckerath, Norbert Peekhaus, Steven M. Larson, David Ulmert, Austin Ho, Ann-Christin Malmborg Hager
Hu11B6 is a monoclonal antibody that internalizes in cells expressing androgen receptor (AR)-regulated prostate specific enzyme human kallikrein 2 (hK2;KLK2). In multiple rodent models, Actinium-225 labeled hu11B6-IgG1([225Ac]hu11B6-IgG1) has shown p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d953bb8075ae7059efcfa2e899a1671d
Autor:
William M, Spees, Guangli, Yang, Darren, Veach, Maria Belen, Rubio, Jason A, Koutcher, William, Bornmann
Publikováno v:
Molecular cancer therapeutics. 2(10)
The synthesis and characterization of 3'-fluoromethotrexate (FMTX), a novel fluorine-labeled analogue of methotrexate, are presented. Molecular modeling studies indicate that the fluorine atom causes only minimal changes in the structure/binding in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffed05aba2f42ab3c54b119336099a68
https://pubmed.ncbi.nlm.nih.gov/14578458
https://pubmed.ncbi.nlm.nih.gov/14578458
Autor:
Alyson, Swimm, Bettina, Bommarius, Yue, Li, David, Cheng, Patrick, Reeves, Melanie, Sherman, Darren, Veach, William, Bornmann, Daniel, Kalman
Publikováno v:
Molecular Biology of the Cell; August 2004, Vol. 15 Issue: 8 p3520-9, 10p