Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Darren, Svirskis"'
Autor:
Svenja Meissner, Salvador Lopez, Shaun Rees, Simon O’Carroll, David Barker, Bruce Harland, Brad Raos, Darren Svirskis
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Neurotrophic growth factor (GF) loaded hydrogels have shown promise as a treatment approach for spinal cord injury (SCI). However, SCI presents complex challenges for the direct administration of treatment due to the spinal cord’s intricat
Externí odkaz:
https://doaj.org/article/a57810a9f4af4b8683cb0276e2670b05
Autor:
Dimitri Daldegan-Bueno, Carina Joy Donegan, Anna Forsyth, Rachael Louise Sumner, Robin J. Murphy, David B. Menkes, William Evans, Nicholas Hoeh, Frederick Sundram, Lisa M. Reynolds, Rhys Ponton, Alana Cavadino, Todd Smith, Partha Roop, Nathan Allen, Binu Abeysinghe, Darren Svirskis, Mahima Bansal, Suresh Muthukumaraswamy
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Major depressive disorder (MDD) poses a significant global health burden with available treatments limited by inconsistent efficacy and notable side effects. Classic psychedelics, including lysergic acid diethylamide (LSD), have g
Externí odkaz:
https://doaj.org/article/70cd426a594a4075b74f8e1ff6061e30
Publikováno v:
IET Power Electronics, Vol 16, Iss 14, Pp 2311-2319 (2023)
Abstract This paper proposes a mutually decoupled transmission and receiver coil (MDC) system to improve the sensitivity of inductively coupled communication. The proposed communication system is intended to be mounted on the frame of a spectacle and
Externí odkaz:
https://doaj.org/article/e07ef4308b7043839d977ffa32b95860
Autor:
Carina Joy Donegan, Dimitri Daldegan-Bueno, Rachael Sumner, David Menkes, William Evans, Nicholas Hoeh, Frederick Sundram, Lisa Reynolds, Rhys Ponton, Alana Cavadino, Todd Smith, Partha Roop, Nathan Allen, Binu Abeysinghe, Darren Svirskis, Anna Forsyth, Mahima Bansal, Suresh Muthukumaraswamy
Publikováno v:
Pilot and Feasibility Studies, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract Background Globally, an estimated 260 million people suffer from depression [1], and there is a clear need for the development of new, alternative antidepressant therapies. In light of problems with the tolerability and efficacy of available
Externí odkaz:
https://doaj.org/article/b33c79e5717541308ff4e24bb008dcfa
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 546 (2024)
Gemcitabine is a nucleoside analog effective against a number of cancers. However, it has an oral bioavailability of less than 10%, due to its high hydrophilicity and low permeability through the intestinal epithelium. Therefore, the aim of this proj
Externí odkaz:
https://doaj.org/article/07f2e5f3eec44ca9a9c09fda16f7086b
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 3, Pp 503-504 (2024)
Externí odkaz:
https://doaj.org/article/71f4788db0b741bea81f132f2cd3d002
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 031505-031505-20 (2023)
Electrical stimulation (ES) shows promise as a therapy to promote recovery and regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) and has been investigated in numerous studies, which date back nearly a cent
Externí odkaz:
https://doaj.org/article/96308cd5896a40dca0cb124f3fae15d7
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 397 (2024)
Background: Although its immunomodulatory properties make thymopentin (TP5) appealing, its rapid metabolism and inactivation in the digestive system pose significant challenges for global scientists. PEGylated niosomal nanocarriers are hypothesized t
Externí odkaz:
https://doaj.org/article/ca7d64b575c343ce96a9b181ceef577c
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the molecular and cellular processes involved in disorders of the nervous system. Adapting these models to a high-throughput format enables simultaneous scr
Externí odkaz:
https://doaj.org/article/a4306f08ab2245b3a71a55ea59f19d92
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2360 (2023)
Hydrogels are homogeneous three-dimensional polymeric networks capable of holding large amounts of water and are widely used in topical formulations. Herein, the physicomechanical, rheological, bioadhesive, and drug-release properties of hydrogels co
Externí odkaz:
https://doaj.org/article/cd99d2e1fb23429d89556d5c0c677f6b