Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Darren, Jolliffe"'
Autor:
Jürgen K Rockstroh, David Asmuth, Giuseppe Pantaleo, Bonaventura Clotet, Daniel Podzamczer, Jan van Lunzen, Keikawus Arastéh, Ronald Mitsuyasu, Barry Peters, Nozza Silvia, Darren Jolliffe, Mats Ökvist, Kim Krogsgaard, Maja A Sommerfelt
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210965 (2019)
BACKGROUND:Vacc-4x, a therapeutic HIV vaccine candidate has previously induced a significant reduction in viral load (VL) set-point compared to placebo upon interruption of combination anti-retroviral therapy (ART) (2007/1 study). This study, (2012/1
Externí odkaz:
https://doaj.org/article/0bf3f95c684d4befbb874ae8332339ff
Autor:
Funda Meric-Bernstam, Jacqui Rowbottom, Bob T. Li, Soham D. Puvvada, Mark Gustavson, Ariadna Mendoza-Naranjo, Darren Jolliffe
Publikováno v:
Journal of Clinical Oncology. 39:TPS3162-TPS3162
TPS3162 Background: There are substantial data suggesting that a subset of human epidermal growth factor receptor 2 (HER2)–activating mutations induce ligand-independent constitutive HER2 signaling and promote oncogenesis. Direct therapeutic target
Autor:
Yunda, Huang, Lily, Zhang, Darren, Jolliffe, Brittany, Sanchez, Grete, Stjernholm, Øyvind, Jelmert, Mats, Ökvist, Maja A, Sommerfelt
Publikováno v:
AIDS research and human retroviruses. 34(3)
Therapeutic vaccination has the potential to contribute to functional HIV cure strategies. However, to show functional HIV cure, study participants must be taken off combination antiretroviral therapy (cART). The availability of suitable biomarkers t
Autor:
Giuseppe Pantaleo, Yunda Huang, Darren Jolliffe, Lily Zhang, Mats Ökvist, Maja A. Sommerfelt, Arnt-Ove Hovden
Publikováno v:
Vaccine. 34(10)
Background In a randomized, double-blind, placebo-controlled phase 2 clinical trial of Vacc-4x, a peptide-based therapeutic HIV-1 p24 Gag vaccine candidate, 135 HIV-infected participants (vaccine:placebo = 92:43) received a series of six immunization
Autor:
Ingebjørg Baksaas, Gerd Fätkenheuer, Giuseppe Pantaleo, Jürgen K. Rockstroh, Barry Peters, Graeme Moyle, W. David Hardy, Jan van Lunzen, Andreas Plettenberg, Adriano Lazzarin, Margaret A. Fischl, Babafemi Taiwo, Birger Sørensen, Kim Ellefsen, Richard B. Pollard, Ronald T. Mitsuyasu, Stefan Persson, Arnt-Ove Hovden, Darren Jolliffe, Bonaventura Clotet, Øyvind Jelmert, Maja A. Sommerfelt, Keikawus Arastéh, Dirk Schürmann, Felipe García, Vidar Wendel-Hansen, Martin Fisher, Daniel Podzamczer, David M. Asmuth
Publikováno v:
Pollard, RB; Rockstroh, JK; Pantaleo, G; Asmuth, DM; Peters, B; Lazzarin, A; et al.(2014). Safety and efficacy of the peptide-based therapeutic vaccine for HIV-1, Vacc-4x: A phase 2 randomised, double-blind, placebo-controlled trial. The Lancet Infectious Diseases, 14(4), 291-300. doi: 10.1016/S1473-3099(13)70343-8. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2r859753
The Lancet. Infectious diseases, vol 14, iss 4
The Lancet. Infectious diseases, vol 14, iss 4
Background: Present combination antiretroviral therapy (cART) alone does not cure HIV infection and requires lifelong drug treatment. The potential role of HIV therapeutic vaccines as part of an HIV cure is under consideration. Our aim was to assess