Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Darrell Yamashiro"'
Autor:
Somnath Tagore, Jovana Pavisic, Aaron T. Griffin, Katherine Janeway, Andrew L. Kung, Filemon Dela Cruz, Alejandro Sweet-Cordero, Inge Behroozfard, Stanley Leung, Alex Lee, Darrell Yamashiro, Julia Glade Bender, Andrea Califano
Publikováno v:
Cancer Research. 82:488-488
Despite many clinical trials, outcome for osteosarcoma (OS) patients remains poor, especially for those with metastatic or relapsed/refractory disease. We leveraged network-based systems biology approaches to discover Master Regulator (MR) proteins r
Autor:
Samuel Z. Soffer, Christina Manley, Darrell Yamashiro, Dorothy H. Rowe, James Moore, Charles J.H. Stolar, Eugene S. Kim, William Middlesworth, Jessica J. Kandel, Kathleen O'Toole, Jianzhong Huang
Publikováno v:
Journal of Pediatric Surgery. 36:357-361
Background/Purpose: Pathologic angiogenesis in tumors is a potential target for novel therapies. Vascular endothelial growth factor (VEGF) is an angiogenic promoter present in a wide variety of human tumors. VEGF is expressed as 4 isoforms; one of th
Autor:
Jianzhong Huang, Christina Manley, Darrell Yamashiro, Kathleen O'Toole, Jin Li, Charles J.H. Stolar, Jessica J. Kandel, Dorothy H. Rowe
Publikováno v:
Journal of Pediatric Surgery. 35:977-981
Background/Purpose: Neuroblastoma is the most common tumor of the abdomen in children. Consistently effective treatments are lacking for aggressive disease. The authors previously reported that therapy with anti-vascular endothelial growth factor (VE
Autor:
Darrell Yamashiro, Mark L. Kayton, Richard Thompson, Jessica J. Kandel, Dorothy H. Rowe, Jianzhong Huang, Andrea Troxel, Kathleen O'Toole, Charles J.H. Stolar
Publikováno v:
Journal of Pediatric Surgery. 35:30-33
Vascular endothelial growth factor (VEGF) has been shown previously to correlate with tumor growth and metastasis in an experimental model of anaplastic Wilms' tumor. The authors hypothesized that treatment with anti-VEGF antibodies would suppress bo
Autor:
Jianzhong Huang, Anna Serur, Jason S. Frischer, Jessica J. Kandel, Angela Kadenhe, Darrell Yamashiro
Publikováno v:
Journal of pediatric surgery. 39(3)
Background/purpose Vascular anomalies are a diverse set of lesions with distinct clinical behaviors, whose biomolecular characteristics are largely undefined. Common hemangiomas proliferate during the first year of life, then involute at a variable p
Autor:
Kimberly W. McCrudden, Darrell Yamashiro, Anna Novikov, Angela Kadenhe, Jianzhong Huang, Benjamin D. Hopkins, Akiko Yokoi, Jessica J. Kandel, Tamara New, William Middlesworth, Jason S. Frischer
Publikováno v:
Journal of pediatric surgery. 38(3)
Hepatoblastoma is the most common primary hepatic malignancy of childhood, frequently presenting as advanced disease. Vascular endothelial growth factor (VEGF) is an endothelial mitogen and survival factor critical to growth and angiogenesis in many
Autor:
Amit Thosani, Kimberly W. McCrudden, Darrell Yamashiro, Eugene S. Kim, Jianzhong Huang, Akiko Yokoi, Christina Manley, Jessica J. Kandel, Kathleen O'Toole, William Middlesworth, Samuel Z. Soffer
Publikováno v:
Journal of pediatric surgery. 37(6)
Background: Advanced hepatoblastoma often is lethal despite current therapies, yet development of novel approaches has been hampered by the lack of biologically relevant models. One new strategy selectively targets endothelium rather than tumor cells
Autor:
Jessica Kandel, Samuel Z. Soffer, Jason Fisher, Bettie M. Steinberg, Richard D. Glick, Jianzhong Huang, Aaron M. Lipskar, Darrell Yamashiro
Publikováno v:
Journal of the American College of Surgeons. 207:S22-S23