Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Darrell R Fisher"'
Autor:
Sofia H L Frost, Shani L Frayo, Brian W Miller, Johnnie J Orozco, Garrett C Booth, Mark D Hylarides, Yukang Lin, Damian J Green, Ajay K Gopal, John M Pagel, Tom A Bäck, Darrell R Fisher, Oliver W Press
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120561 (2015)
Pretargeted radioimmunotherapy (PRIT) is a multi-step method of selectively delivering high doses of radiotherapy to tumor cells while minimizing exposure to surrounding tissues. Yttrium-90 (90Y) and lutetium-177 (177Lu) are two of the most promising
Externí odkaz:
https://doaj.org/article/feaef0190b0a45d09f0422717c6da81b
Autor:
Johnnie J Orozco, Ethan R Balkin, Ted A Gooley, Aimee Kenoyer, Donald K Hamlin, D Scott Wilbur, Darrell R Fisher, Mark D Hylarides, Mazyar Shadman, Damian J Green, Ajay K Gopal, Oliver W Press, John M Pagel
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113601 (2014)
Radioimmunotherapy (RIT) for treatment of hematologic malignancies has primarily employed monoclonal antibodies (Ab) labeled with 131I or 90Y which have limitations, and alternative radionuclides are needed to facilitate wider adoption of RIT. We the
Externí odkaz:
https://doaj.org/article/4a6a92e17f094f61830dbc58280f0cd7
Autor:
Robin Peter, Brenda M. Sandmaier, Michael P. Dion, Sofia H. L. Frost, Erlinda B. Santos, Aimee Kenoyer, Donald K. Hamlin, D. Scott Wilbur, Robert D. Stewart, Darrell R. Fisher, Kai Vetter, Youngho Seo, Brian W. Miller
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Targeted radiopharmaceutical therapy with alpha-particle emitters (αRPT) is advantageous in cancer treatment because the short range and high local energy deposition of alpha particles enable precise radiation delivery and efficient tumor c
Externí odkaz:
https://doaj.org/article/19699be21fb4471dae94c49d02e265c3
Autor:
Phuong Vo, Ted A. Gooley, Joseph G. Rajendran, Darrell R. Fisher, Johnnie J. Orozco, Damian J. Green, Ajay K. Gopal, Robyn Haaf, Margaret Nartea, Rainer Storb, Frederick R. Appelbaum, Oliver W. Press, John M. Pagel, Brenda M. Sandmaier
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
Outcomes of patients with persistent high-risk leukemia or myelodysplasia prior to allogeneic hematopoietic cell transplantation are dismal. We therefore conducted a phase I trial evaluating the use of CD45-targeted radiotherapy preceding hematopoiet
Externí odkaz:
https://doaj.org/article/5305b45938ed4d9fbd2343bde3761ae8
Autor:
Jaline Broqueza, Chandra B. Prabaharan, Kevin J. H. Allen, Rubin Jiao, Darrell R. Fisher, Ryan Dickinson, Valerie MacDonald-Dickinson, Maruti Uppalapati, Ekaterina Dadachova
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 10 (2021)
Background: Osteosarcoma (OS) has an overall patient survival rate of ~70% with no significant improvements in the last two decades, and novel effective treatments are needed. OS in companion dogs is phenotypically close to human OS, which makes a co
Externí odkaz:
https://doaj.org/article/1fee13fead964d35bc77671f57e68319
Publikováno v:
Health Physics. 123:343-347
Extravasation during radiopharmaceutical injection may occur with a frequency of more than 10%. In these cases, radioactivity remains within tissue and deposits unintended radiation dose. Characterization of extravasations is a necessary step in accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a97fe810aefcebf6635d332881063f
https://doi.org/10.1097/hp.0000000000001600
https://doi.org/10.1097/hp.0000000000001600
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Pretargeted radioimmunotherapy (PRIT) has been investigated as a multi-step approach to decrease relapse and toxicity for high-risk acute myeloid leukemia (AML). Relevant factors including endogenous biotin and immunogenicity, however, have limited t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cb196c04e590eb312858a4d9061fed
https://doi.org/10.1158/1535-7163.c.6542662
https://doi.org/10.1158/1535-7163.c.6542662
Autor:
John M. Pagel, Oliver W. Press, Brenda Sandmaier, Brian G. Till, Ajay K. Gopal, Damian J. Green, K. Dane Wittrup, Kelly D. Orcutt, D. Scott Wilbur, Donald K. Hamlin, Ethan R. Balkin, Darrell R. Fisher, Mark D. Hylarides, Alexandra H. Hernandez, Margaret E. Nartea, Rosario Guel, Shyril O'Steen, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco
Supplementary Materials, Methods and relevant AA sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c057d8965675ca7f790ca8236eb48a
https://doi.org/10.1158/1535-7163.22520518.v1
https://doi.org/10.1158/1535-7163.22520518.v1
Autor:
Oliver W. Press, Brian G. Till, Amelia Waltman, Theodore A. Gooley, Mark D. Hylarides, Darrell R. Fisher, Donald K. Hamlin, D. Scott Wilbur, Yukang Lin, Aimee L. Kenoyer, Johnnie J. Orozco, Ajay K. Gopal, Damian J. Green, Shyril O'Steen
Table S1 presents mouse survival data for in vivo experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1f8931fda4e9dec0f52f77d94c1a28
https://doi.org/10.1158/0008-5472.22414092.v1
https://doi.org/10.1158/0008-5472.22414092.v1
Autor:
Oliver W. Press, K. Dane Wittrup, D. Scott Wilbur, Kelly D. Orcutt, Shyril O'Steen, Brian G. Till, Johnnie J. Orozco, Theodore A. Gooley, Ajay K. Gopal, Mark D. Hylarides, Aimee L. Kenoyer, Sofia H.L. Frost, Darrell R. Fisher, Donald K. Hamlin, Yukang Lin, Shani L. Frayo, Damian J. Green
Figures including: Supplemental Figure 1- Dose finding pharmacokinetics. Supplemental Figure 2- Dose finding tissue biodistribution. Supplemental Figure 3- body weight over time in a therapy study. Supplemental Figure 4- blood counts over time in a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27fa9ad6c582f79e53958516ac3c2d49
https://doi.org/10.1158/0008-5472.22413027
https://doi.org/10.1158/0008-5472.22413027