Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Darrell M, Wilson"'
Autor:
Felipe de Jesus Cortez, David Gebhart, Devangkumar Tandel, Peter V. Robinson, David Seftel, Darrell M. Wilson, David M. Maahs, Bruce A. Buckingham, Kevin W.P. Miller, Cheng-ting Tsai
Publikováno v:
SLAS Technology, Vol 27, Iss 1, Pp 26-31 (2022)
Screening for islet autoantibody markers to identify individuals who are at high risk for developing type 1 diabetes (T1D), often years in advance of clinical symptoms, is both a challenge and a necessity. Identifying high-risk individuals not only r
Externí odkaz:
https://doaj.org/article/bac85e372e104ead89885f5fa5c4a5df
Autor:
Carla J. Greenbaum, Elisavet Serti, Katharina Lambert, Lia J. Weiner, Sai Kanaparthi, Sandra Lord, Stephen E. Gitelman, Darrell M. Wilson, Jason L. Gaglia, Kurt J. Griffin, William E. Russell, Philip Raskin, Antoinette Moran, Steven M. Willi, Eva Tsalikian, Linda A. DiMeglio, Kevan C. Herold, Wayne V. Moore, Robin Goland, Mark Harris, Maria E. Craig, Desmond A. Schatz, David A. Baidal, Henry Rodriguez, Kristina M. Utzschneider, Hendrik J. Nel, Carol L. Soppe, Karen D. Boyle, Karen Cerosaletti, Lynette Keyes-Elstein, S. Alice Long, Ranjeny Thomas, James G. McNamara, Jane H. Buckner, Srinath Sanda, for the ITN058AI EXTEND Study Team
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Background IL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in
Externí odkaz:
https://doaj.org/article/083a57294536479793c92cf07ad43e13
Autor:
Felipe de Jesus Cortez, David Gebhart, Peter V Robinson, David Seftel, Narges Pourmandi, Jordan Owyoung, Carolyn R Bertozzi, Darrell M Wilson, David M Maahs, Bruce A Buckingham, John R Mills, Matthew M Roforth, Sean J Pittock, Andrew McKeon, Kara Page, Wendy A Wolf, Srinath Sanda, Cate Speake, Carla J Greenbaum, Cheng-Ting Tsai
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242049 (2020)
Islet autoantibodies are predominantly measured by radioassay to facilitate risk assessment and diagnosis of type 1 diabetes. However, the reliance on radioactive components, large sample volumes and limited throughput renders radioassay testing cost
Externí odkaz:
https://doaj.org/article/3a43e86479fd4577be2fc7ea1a034780
Autor:
Kevan C. Herold, Anette-Gabriele Ziegler, Darrell M. Wilson, Diane K. Wherrett, John M Wentworth, Jay S. Skyler, Phillip Raskin, Andrew B. Muir, Antoinette M. Moran, Wayne V Moore, Daniel J. Moore, Sandra M. Lord, S. Alice Long, Peter S. Linsley, Ingrid M. Libman, Jeffrey P Krischer, Michael J. Haller, Carla J. Greenbaum, Peter A. Gottlieb, Robin S. Goland, Stephen E. Gitelman, Laura A. Cooney, Mark S. Anderson, Brian N. Bundy, William E. Russell
Objective Previous studies showed that inhibiting lymphocyte costimulation reduces declining beta cell function in individuals newly-diagnosed with type 1 diabetes. We tested whether abatacept would delay or prevent progression of type 1 diabetes fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e612bbc18c514cf7dd93b604e719af2d
https://doi.org/10.2337/figshare.22009586
https://doi.org/10.2337/figshare.22009586
Autor:
Laura Pyle, Tim Vigers, Cari Berget, Darrell M. Wilson, Laurel H. Messer, Rayhan A. Lal, Gregory P. Forlenza, Bruce A. Buckingham, R. Paul Wadwa, Korey K. Hood, Marina Basina, David M. Maahs, Kimberly A. Driscoll
Publikováno v:
Diabetes Technol Ther
Background Hybrid Closed Loop (HCL) systems aid individuals with type 1 diabetes in improving glycemic control, however, sustained use over time has not been consistent for all users. This study developed and validated prognostic models for successfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ea0861287a120c1e0b2328ec5cc6946
https://pubmed.ncbi.nlm.nih.gov/34780306
https://pubmed.ncbi.nlm.nih.gov/34780306
Autor:
Type I Diabetes TrialNet Study Group, Massimo Pietropaolo, Patrick W. Nelson, Mark A. Atkinson, Desmond A. Schatz, Michael J. Haller, Sandra M. Lord, Carla J. Greenbaum, Jessica L. Dunne, Kevan C. Herold, Jennifer L. Sherr, Siripoom V. McKay, Madhuri M. Vasudevan, Andrea K. Steck, David Scheinker, Destiny Anyaiwe, Shuai Huang, Maria Acevedo-Calado, Susan L. Pietropaolo, Darrell M. Wilson
OBJECTIVE Continuous glucose monitoring (CGM) parameters may identify subjects at risk of progressing to overt type 1 diabetes. We aimed to determine whether CGM metrics provides additional insights into progression to clinical Stage 3 type 1 diabete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecafda4083adf8e03e15b3babc92b74
https://doi.org/10.2337/figshare.21667085
https://doi.org/10.2337/figshare.21667085
Publikováno v:
Diabetes. 71
Type 2 diabetes mellitus (T2D) in youth has become an increasingly pressing issue over the last two decades. Emerging data from adult studies show associations between T2D and neighborhood characteristics; less is known about these effects on the ped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43461ee11f48cd7093961a4f3700671f
https://doi.org/10.2337/db22-1000-p
https://doi.org/10.2337/db22-1000-p
Autor:
Antoinette Moran, S. Alice Long, Philip Raskin, James McNamara, William E. Russell, Carol L. Soppe, Sai Kanaparthi, Elisavet Serti, Hendrik J. Nel, Kevan C. Herold, Sandra Lord, Lia J Weiner, Steven M. Willi, Lynette Keyes-Elstein, Kurt J Griffin, Robin Goland, Ranjeny Thomas, Stephen E. Gitelman, Mark Harris, Henry Rodriguez, Karen Cerosaletti, Linda A. DiMeglio, Darrell M. Wilson, Itn Ai Extend Study Team, Wayne V. Moore, Srinath Sanda, Carla J. Greenbaum, Maria E. Craig, David A. Baidal, Kristina M. Utzschneider, Jason L. Gaglia, Katharina Lambert, Eva Tsalikian, Karen D. Boyle, Desmond A. Schatz, Jane H. Buckner
Publikováno v:
JCI Insight
JCI insight, vol 6, iss 21
JCI insight, vol 6, iss 21
Background IL-6 receptor (IL-6R) signaling drives development of T cell populations important to type 1 diabetes pathogenesis. We evaluated whether blockade of IL-6R with monoclonal antibody tocilizumab would slow loss of residual β cell function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be015273c4208eb40c963e69de86cd2c
http://europepmc.org/articles/PMC8663550
http://europepmc.org/articles/PMC8663550
Autor:
Korey K. Hood, David M. Maahs, Rayhan A. Lal, Darrell M. Wilson, Marina Basina, Bruce A. Buckingham
Publikováno v:
Diabetes Care
OBJECTIVE In September 2016, the U.S. Food and Drug Administration approved the Medtronic 670G “hybrid” closed-loop system. In Auto Mode, this system automatically controls basal insulin delivery based on continuous glucose monitoring data but re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c93ea4e1836d7792fcc0975c5d862d7
https://doi.org/10.2337/dc19-0855
https://doi.org/10.2337/dc19-0855
Autor:
Antoinette Moran, S. Alice Long, Susan Geyer, Megan V. Warnock, Linda A. DiMeglio, Henry Rodriguez, Jennifer B. Marks, Dorothy J. Becker, David A. Baidal, J Lori Blanchfield, Darrell M. Wilson, Peter A. Gottlieb, Stephen E. Gitelman, Desmond A. Schatz, Brian N. Bundy, Jessica L. Miller, Mark A. Atkinson, Michael J. Haller, Jay S. Skyler, Carla J. Greenbaum, Robin Goland, Jeffrey P. Krischer, Kevan C. Herold, William E. Russell
Publikováno v:
Diabetes
A three-arm, randomized, double-masked, placebo-controlled phase 2b trial performed by the Type 1 Diabetes TrialNet Study Group previously demonstrated that low-dose anti-thymocyte globulin (ATG) (2.5 mg/kg) preserved β-cell function and reduced HbA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e408ecd37f3201a76d7f54cd07b1a446
http://europepmc.org/articles/PMC6610026
http://europepmc.org/articles/PMC6610026