Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Darrell L, Ellsworth"'
Autor:
Darrell L. Ellsworth, Heather L. Blackburn, Craig D. Shriver, Shahrooz Rabizadeh, Patrick Soon-Shiong, Rachel E. Ellsworth
Publikováno v:
Clinical and Translational Medicine, Vol 6, Iss 1, Pp 1-19 (2017)
Abstract Extensive genomic and transcriptomic heterogeneity in human cancer often negatively impacts treatment efficacy and survival, thus posing a significant ongoing challenge for modern treatment regimens. State-of-the-art DNA- and RNA-sequencing
Externí odkaz:
https://doaj.org/article/fecc57f36a404539abd61de8ed0951bc
Autor:
Heather L. Blackburn, Seóna McErlean, Gera L. Jellema, Ryan van Laar, Marina N. Vernalis, Darrell L. Ellsworth
Publikováno v:
Genomics Data, Vol 4, Iss C, Pp 50-53 (2015)
Heart disease and related sequelae are a leading cause of death and healthcare expenditure throughout the world. Although many patients opt for surgical interventions, lifestyle modification programs focusing on nutrition and exercise have shown subs
Externí odkaz:
https://doaj.org/article/27808d9fd81b4ec0aa9363b2c1bd0064
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 11 (2017)
Metastasis is a multistep process that is not well understood. Colonization of a secondary organ requires specific molecular alterations of the host microenvironment. To determine the temporal and spatial changes associated with metastatic disseminat
Externí odkaz:
https://doaj.org/article/de4db9f190f14bedb994784f3b9b0e20
Autor:
Darrell L. Ellsworth, Craig D. Shriver, Nicholas S. Costantino, Paul J. Kostyniak, Rachel E. Ellsworth, Lai-Har Chi
Publikováno v:
Environmental Toxicology. 33:876-884
Agricultural pesticides are abundant environmental contaminants worldwide, prompting interest in studying their possible detrimental health effects. We examined organochlorine residues by quadrant (n = 245) in breast adipose tissues from 51 women wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c8091c53967d85d71b2b8fc11b795a
https://doi.org/10.1002/tox.22573
https://doi.org/10.1002/tox.22573
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 3 (2009)
Pathological grade is a useful prognostic factor for stratifying breast cancer patients into favorable (low-grade, well-differentiated tumors) and less favorable (high-grade, poorly-differentiated tumors) outcome groups. Under the current system of t
Externí odkaz:
https://doaj.org/article/b0e161f67a0c493ca376a6cc0058ac09
Publikováno v:
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology
Journal of Oncology
Triple negative breast cancer (TNBC), representing 10-15% of breast tumors diagnosed each year, is a clinically defined subtype of breast cancer associated with poor prognosis. The higher incidence of TNBC in certain populations such as young women a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab0215825d1b583d7a090ef9f4a3d1e
https://doaj.org/article/6481287a412f45f5973be97d28988f64
https://doaj.org/article/6481287a412f45f5973be97d28988f64
Autor:
Heather L. Blackburn, Renata J.M. Engler, Mariam Kashani, Marina N. Vernalis, Darrell L. Ellsworth, N. S. Costantino
Publikováno v:
Obesity Science & Practice. 2:282-292
SummaryObjective Metabolic dysfunction characterized by insulin resistance (IR) is an important risk factor for type-2 diabetes and coronary artery disease (CAD). The aim of this study was to determine if clinical lifestyle interventions differing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5f07f7c52937f49804444f3a4bab24
https://doi.org/10.1002/osp4.54
https://doi.org/10.1002/osp4.54
Publikováno v:
Cancer Research. 76:P4-10
Background: Survival rates for patients diagnosed with invasive breast cancer have increased dramatically, yet survivors often face a host of adverse health effects. Factors such as obesity, physical inactivity and tobacco use may contribute to decre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b77321752a186ce31a91ee5c0d9303c0
https://doi.org/10.1158/1538-7445.sabcs15-p4-10-08
https://doi.org/10.1158/1538-7445.sabcs15-p4-10-08
Publikováno v:
Cancer Research. 79:P5-06
Agricultural pesticides are abundant environmental contaminants worldwide, prompting interest in studying their possible detrimental health effects. We examined organochlorine residues by quadrant (n = 245) in breast adipose tissues from 51 women wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c766c39cda3da578356c981089d0cb5
https://doi.org/10.1158/1538-7445.sabcs18-p5-06-02
https://doi.org/10.1158/1538-7445.sabcs18-p5-06-02
Autor:
Marina N. Vernalis, Kimberly A. Mamula, Renata J.M. Engler, Ryan van Laar, Fionnuala A. McDyer, Darrell L. Ellsworth, Nicholas S. Costantino, Heather L. Blackburn, Gera L. Jellema
Publikováno v:
Obesity. 23:1312-1319
Objective To examine relationships between weight loss through changes in lifestyle and peripheral blood gene expression profiles. Methods A prospective nonrandomized trial was conducted over 1 year in participants undergoing intensive lifestyle modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2173832b7d10b4c9a4e291a5bcdaffb8
https://doi.org/10.1002/oby.21079
https://doi.org/10.1002/oby.21079