Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Darrell K. Murray"'
Publikováno v:
Cancer Detection and Prevention. 26:229-237
Transforming growth factor beta-1 (TGFbeta-1) and tumor necrosis factor alpha (TNF-alpha), an activator of nuclear factor kappa B (NF-kappaB), modulate apoptosis and/or cell growth. This study was designed to investigate the activity of NF-kappaB and
Publikováno v:
The Prostate. 44:287-295
BACKGROUND Many human prostate cancer cells have escaped the apoptotic effects of natural regulators of cell growth such as transforming growth factor βl (TGF β-1) and tumor necrosis factor (TNF). METHODS Prostate cancer cell growth was investigate
Publikováno v:
Thrombosis Research. 85:399-411
Procoagulant albumin (Pro-Alb) is an anionic form of albumin isolated from normal human plasma that regulates vascular endothelial cell hemostatic properties, including induction of tissue factor activity. We investigated the biochemical modification
Publikováno v:
Metabolism. 45:293-299
We have observed that nonesterified fatty acids (NEFA) inhibit testosterone synthesis in response to luteinizing hormone (LH) in mouse Leydig cells, possibly by affecting cholesterol utilization or endogenous concentrations. We have now studied the i
Publikováno v:
Life Sciences. 46:1843-1849
The mechanism of the inhibitory action of glucocorticoids on glucose uptake is incompletely understood. Treatment with corticosteroids of cells in which glucose uptake is stimulated at insulin postbinding and postreceptor sites may clarify the site o
Publikováno v:
Cancer detection and prevention. 26(2)
We have investigated the effect of antioxidant-induced apoptosis in human prostate cancer cell lines that is augmented by testosterone (T). In this study, DU-145 (androgen unresponsive), ALVA-101 (partially androgen responsive), and LNCaP (androgen r
Autor:
Darrell K. Murray, Robert A. Stephenson, J T Wu, Aruna T. Bansal, A W Meikle, Richard G. Middleton
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(3)
Both benign prostatic hyperplasia and prostate-specific antigen (PSA) have been shown to increase with age and with prostate volume in men, but the influence of heredity on these relationships is not completely understood. This study has two aims: 1)
Autor:
Darrell K. Murray, Steven M. Loop, A. Wayne Meikle, Richard E. Swope, Diana Y. Yin, Dan Fullmer
Publikováno v:
Metabolism: clinical and experimental. 48(9)
Transforming growth factor beta-1 (TGFbeta-1) causes apoptosis of many epithelial cells, including the prostate, but other secondary effects of TGFbeta-1 may be important in carcinogenesis. In a human prostate cancer cell line (ALVA-101), we determin
Autor:
Robert A. Stephenson, Darrell K. Murray, Aruna T. Bansal, A. Wayne Meikle, Richard G. Middleton
Publikováno v:
Urology. 53(4)
Objectives. Both benign prostatic hyperplasia and lower urinary tract symptoms (LUTS) have been shown to increase with age in men, but a causal relationship between prostate volume and symptoms has not been established. This study had two aims, to in
Publikováno v:
Endocrinology. 111:452-455
Adrenalectomy produces a significant fall in the sphingomyelin and cholesterol content of ghosts isolated from rat epididymal fat cells. Previous studies from this laboratory have demonstrated an effect of dexamethasone in vitro to increase the sphin