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pro vyhledávání: '"Darragh J Crowley"'
Autor:
Joseph P Sanderson, Darragh J Crowley, Guy E Wiedermann, Laura L Quinn, Katherine L Crossland, Helen M Tunbridge, Terri V Cornforth, Christopher S Barnes, Tina Ahmed, Karen Howe, Manoj Saini, Rachel J Abbott, Victoria E Anderson, Barbara Tavano, Miguel Maroto, Andrew B Gerry
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
A substantial obstacle to the success of adoptive T cell-based cancer immunotherapy is the sub-optimal affinity of T-cell receptors (TCRs) for most tumor antigens. Genetically engineered TCRs that have enhanced affinity for specific tumor peptide-MHC
Externí odkaz:
https://doaj.org/article/e35306bbdb1849d39ee4052270c1a7e2