Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Darragh E. Crosbie"'
Autor:
Matthew Campbell, Lawrence C. S. Tam, James Keaney, W. Daniel Stamer, Peter Humphries, Darragh E. Crosbie
Publikováno v:
Magnetic Resonance Imaging. 59:10-16
Purpose Here, we are testing the hypothesis that dynamic contrast enhanced MRI (DCE-MRI) is a useful approach for non-invasively evaluating age-related changes in aqueous humor outflow and its contribution to elevated intraocular pressure in the DBA/
Publikováno v:
Progress in Retinal and Eye Research. 62:120-133
Protein levels of endothelial tight-junctions of the inner retinal microvasculature, together with those of Schlemm's canal, can be readily manipulated by RNA interference (RNAi), resulting in the paracellular clefts between such cells to be reversib
Autor:
Matthew Campbell, Joseph M. Sherwood, Elke Lütjen-Drecoll, Lawrence C. S. Tam, Cassandra Flügel-Koch, Colm O'Brien, Deborah Wallace, Anna-Sophia Kiang, Paul S. Cassidy, Ester Reina-Torres, Peter Humphries, Jeffrey O'Callaghan, Darryl R. Overby, W. Daniel Stamer, Marian M. Humphries, Darragh E. Crosbie
Publikováno v:
Human Molecular Genetics
Intraocular pressure (IOP) is maintained as a result of the balance between production of aqueous humour (AH) by the ciliary processes and hydrodynamic resistance to its outflow through the conventional outflow pathway comprising the trabecular meshw
Autor:
Darragh E. Crosbie, Anna-Sophia Kiang, Matthew S. Lawrence, Elke Lütjen-Drecoll, Colm O'Brien, Jeffrey O'Callaghan, Kristin Perkumas, Ester Reina-Torres, W. Daniel Stamer, Marian M. Humphries, Joseph M. Sherwood, Matthew Campbell, John J. Callanan, Lawrence C. S. Tam, Darryl R. Overby, Cassandra Flügel-Koch, Peter Humphries, Paul S. Cassidy, A. Thomas Read, C. Ross Ethier
Publikováno v:
Scientific Reports
The juxtacanalicular connective tissue of the trabecular meshwork together with inner wall endothelium of Schlemm’s canal (SC) provide the bulk of resistance to aqueous outflow from the anterior chamber. Endothelial cells lining SC elaborate tight
Autor:
Natalie Hudson, Darragh E. Crosbie, Marian M. Humphries, Teresa Loftus, Jacqueline McDaid, John J. Callanan, Peter Humphries, Michael A. Farrell, Matthew Campbell, James Keaney, Dominic M. Walsh, Florike Sheehan, Francesca Brett, Tiernan T. O'Malley
Publikováno v:
Science Advances
Size-selective and passive paracellular diffusion of amyloid-β across tight junctions of the blood-brain barrier in Alzheimer’s disease.
The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and protecting neural tissue
The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and protecting neural tissue