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pro vyhledávání: '"Darra M. Waller"'
Autor:
Lori L. Lopresti-Morrow, Kevin Daniel Freeman-Cook, Joel R. Hardink, Elaine M. Greer, Amy S. Antipas, Gary J. Martinelli, Jennifer L. Liras, Fouad Janat, Donald G. Robertson, Jayvardhan Pandit, Kaushik Datta, Sue A. Yocum, James T. Downs, Darra M. Waller, Diana Sperger, Lawrence A. Reiter, Ellen R. Laird, Martin A. Berliner, Peter G. Mitchell, Michael D. Forman, Marcie L. Vaughn-Bowser, James D. Eskra, Nandell F. Keene, Roberto E. Guzman, Christopher S. Jones
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(22)
Using SAR from two related series of pyrimidinetrione-based inhibitors, compounds with potent MMP-13 inhibition and >100-fold selectivity against other MMPs have been identified. Despite high molecular weights, c log Ps, and polar surface areas, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a677dbc57c5181a3a9927f482718a66
https://pubmed.ncbi.nlm.nih.gov/16942871
https://pubmed.ncbi.nlm.nih.gov/16942871
