Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Darold R, Spillman"'
Autor:
Terrence T. Roh, Aneesh Alex, Prasanna M. Chandramouleeswaran, Janet E. Sorrells, Alexander Ho, Rishyashring R. Iyer, Darold R. Spillman, Jr., Marina Marjanovic, Jason E. Ekert, BanuPriya Sridharan, Balabhaskar Prabhakarpandian, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103280- (2024)
The DNA damage response (DDR) is a fundamental readout for evaluating efficacy of cancer therapeutics, many of which target DNA associated processes. Current techniques to evaluate DDR rely on immunostaining for phosphorylated histone H2AX (γH2AX),
Externí odkaz:
https://doaj.org/article/f2e4f48cd93a4b6196f8b2536ff8af15
Autor:
Rishyashring R. Iyer, Lingxiao Yang, Janet E. Sorrells, Eric J. Chaney, Darold R. Spillman Jr., Stephen A. Boppart
Publikováno v:
APL Photonics, Vol 9, Iss 7, Pp 076114-076114-16 (2024)
The applications of ultrafast optics to biomedical microscopy have expanded rapidly in recent years, including interferometric techniques like optical coherence tomography and microscopy (OCT/OCM). The advances of ultra-high resolution OCT and the in
Externí odkaz:
https://doaj.org/article/6f3e61206c2a4f709e0efb15db0ccb58
Autor:
Kajari Bera, Renán A. Rojas-Gómez, Prabuddha Mukherjee, Corey E. Snyder, Edita Aksamitiene, Aneesh Alex, Darold R. Spillman, Marina Marjanovic, Ahmed Shabana, Russell Johnson, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The COVID-19 pandemic triggered the resurgence of synthetic RNA vaccine platforms allowing rapid, scalable, low-cost manufacturing, and safe administration of therapeutic vaccines. Self-amplifying mRNA (SAM), which self-replicates upon deliv
Externí odkaz:
https://doaj.org/article/9fc1328809a0480cb6006ae1bf4fb049
Autor:
Rishyashring R. Iyer, Janet E. Sorrells, Lingxiao Yang, Eric J. Chaney, Darold R. Spillman, Brian E. Tibble, Carlos A. Renteria, Haohua Tu, Mantas Žurauskas, Marina Marjanovic, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Label-free optical microscopy has matured as a noninvasive tool for biological imaging; yet, it is criticized for its lack of specificity, slow acquisition and processing times, and weak and noisy optical signals that lead to inaccuracies in
Externí odkaz:
https://doaj.org/article/b3bf0c28b91e4f818ade00ca9b92555c
Autor:
Jungeun Won, Wenzhou Hong, Pawjai Khampang, Darold R. Spillman, Samuels Marshall, Ke Yan, Ryan G. Porter, Michael A. Novak, Joseph E. Kerschner, Stephen A. Boppart
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Studying the impact of antibiotic treatment on otitis media (OM), the leading cause of primary care office visits during childhood, is critical to develop appropriate treatment strategies. Tracking dynamic middle ear conditions during antibi
Externí odkaz:
https://doaj.org/article/c31e0027d33d4f1e97ba8979ecd33d28
Autor:
David Adams, Jose Rico-Jimenez, Jang Hyuk Lee, Aneesh Alex, Salma Musaad, Eric Chaney, Ronit Barkalifa, Eric Olson, Marina Marjanovic, Zane Arp, Stephen A Boppart, Darold R Spillman Jr
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
Objective Impaired diabetic wound healing is one of the serious complications associated with diabetes. In patients with diabetes, this impairment is characterized by several physiological abnormalities such as metabolic changes, reduced collagen pro
Externí odkaz:
https://doaj.org/article/c8746c5681c149ba88036e26357201c0
Autor:
Jungeun Won, Guillermo L. Monroy, Roshan I. Dsouza, Darold R. Spillman, Jonathan McJunkin, Ryan G. Porter, Jindou Shi, Edita Aksamitiene, MaryEllen Sherwood, Lindsay Stiger, Stephen A. Boppart
Publikováno v:
Biosensors, Vol 11, Iss 5, p 143 (2021)
A middle ear infection is a prevalent inflammatory disease most common in the pediatric population, and its financial burden remains substantial. Current diagnostic methods are highly subjective, relying on visual cues gathered by an otoscope. To add
Externí odkaz:
https://doaj.org/article/2c40505ea4f140eea480bbcec2ec3e03
Autor:
Alexander Ho, Jindou Shi, Eric J. Chaney, Corey Snyder, Aneesh Alex, Remben Talaban, Janet Sorrells, Darold R. Spillman, Marina Marjanovic, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXI.
Autor:
Jindou Shi, Alexander Ho, Corey E. Snyder, Eric J. Chaney, Janet E. Sorrells, Aneesh Alex, Remben V. Talaban, Darold R. Spillman, Marina Marjanovic, Steve R. Hood, Stephen A. Boppart
Publikováno v:
Multimodal Biomedical Imaging XVIII.
Autor:
Guillermo L. Monroy, Sean T. Fitzgerald, Andrea Locke, Jungeun Won, Darold R. Spillman, Jr., Alexander Ho, Farzana R. Zaki, Honggu Choi, Eric J. Chaney, Jay A. Werkhaven, Kevin M. Mason, Anita Mahadevan-Jansen, Stephen A. Boppart
Publikováno v:
Frontiers in photonics. 3
Otitis media (OM) is a common disease of the middle ear, affecting 80% of children before the age of three. The otoscope, a simple illuminated magnifier, is the standard clinical diagnostic tool to observe the middle ear. However, it has limited cont