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Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data.

Autor: Darmofal M; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine; New York, NY 10065, USA., Suman S; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Atwal G; Computational Biology Program, Ontario Institute for Cancer Research; Toronto, ON M5G 0A3, Canada.; Department of Molecular Genetics, University of Toronto; Toronto, ON M5S 1A8, Canada.; Vector Institute; Toronto, ON M5G 1M1, Canada., Chen JF; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Chang JC; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Toomey M; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine; New York, NY 10065, USA., Vakiani E; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Varghese AM; Department of Medicine, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Rema AB; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Syed A; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Schultz N; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Berger M; Department of Pathology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA., Morris Q; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center; New York, NY 10065, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Sep 10. Date of Electronic Publication: 2023 Sep 10.