Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Darmanin-Sheehan A"'
Autor:
Zhenwei Su, Jonathan Brooks, Jeffrey Pelker, Tatyana Andreyeva, Hanna Sobon, Roger Gifford, Matthew Powers, Jing Wang, Corey Dower, Martin Hegen, Dean Messing, Alfredo Darmanin Sheehan, Joseph J Brennan
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280590 (2023)
C-C motif chemokine receptor-like 2 (CCRL2) is a non-signaling 7 transmembrane receptor that binds chemotactic ligands to shape leukocyte recruitment to sites of inflammation. However, there is a lack of consensus on the ligands that directly bind CC
Externí odkaz:
https://doaj.org/article/706fbbb9092845e5af906b0160784666
Autor:
Adam R. Root, Gurkan Guntas, Madan Katragadda, James R. Apgar, Jatin Narula, Chew Shun Chang, Sara Hanscom, Matthew McKenna, Jason Wade, Caryl Meade, Weijun Ma, Yongjing Guo, Yan Liu, Weili Duan, Claire Hendershot, Amy C. King, Yan Zhang, Eric Sousa, Amy Tam, Susan Benard, Han Yang, Kerry Kelleher, Fang Jin, Nicole Piche-Nicholas, Sinead E. Keating, Fernando Narciandi, Rosemary Lawrence-Henderson, Maya Arai, Wayne R. Stochaj, Kristine Svenson, Lidia Mosyak, Khetemcnee Lam, Christopher Francis, Kimberly Marquette, Liliana Wroblewska, H. Lily Zhu, Alfredo Darmanin Sheehan, Edward R. LaVallie, Aaron M. D’Antona, Alison Betts, Lindsay King, Edward Rosfjord, Orla Cunningham, Laura Lin, Puja Sapra, Lioudmila Tchistiakova, Divya Mathur, Laird Bloom
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of hybridoma, phage display and rational design protein engineering, we ha
Externí odkaz:
https://doaj.org/article/25a52ae4f12b462d933f760c7786789d
Autor:
Townsend, Sue, Fennell, Brian J., Apgar, James R., Lambert, Matthew, McDonnell, Barry, Grant, Joanne, Wade, Jason, Franklin, Edward, Foy, Niall, Shúilleabháin, Deirdre Ní, Fields, Conor, Darmanin-Sheehan, Alfredo, King, Amy, Paulsen, Janet E., Hickling, Timothy P., Tchistiakova, Lioudmila, Cunningham, Orla, Finlay, William J. J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2015 Dec . 112(50), 15354-15359.
Externí odkaz:
https://www.jstor.org/stable/26466600
Autor:
Ronan O’Dwyer, Marina Kovaleva, Jiquan Zhang, John Steven, Emma Cummins, Deborah Luxenberg, Alfredo Darmanin-Sheehan, Miguel F. Carvalho, Matthew Whitters, Kenneth Saunders, Caroline J. Barelle
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its
Externí odkaz:
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b
Autor:
Fennell, B.J., Darmanin-Sheehan, A., Hufton, S.E., Calabro, V., Wu, L., Müller, M.R., Cao, W., Gill, D., Cunningham, O., Finlay, W.J.J.
Publikováno v:
In Journal of Molecular Biology 2010 400(2):155-170
Autor:
Finlay, William J. †, Cunningham, Orla †, Lambert, Matthew A., Darmanin-Sheehan, Alfredo, Liu, Xuemei, Fennell, Brian J., Mahon, Ciara M., Cummins, Emma, Wade, Jason M., O'Sullivan, Cliona M., Tan, Xiang Yang, Piche, Nicole, Pittman, Debra D., Paulsen, Janet, Tchistiakova, Lioudmila, Kodangattil, Sreekumar, Gill, Davinder, Hufton, Simon E. ⁎
Publikováno v:
In Journal of Molecular Biology 2009 388(3):541-558
Autor:
Orla Cunningham, Eric Sousa, Susan Benard, Yongjing Guo, C.M. Francis, Puja Sapra, Laura Lin, Lindsay King, Fang Jin, Weijun Ma, Aaron M. D’Antona, Nicole Piche-Nicholas, Sinead E. Keating, Sara Hanscom, Gurkan Guntas, Wayne Stochaj, Khetemcnee Lam, Claire Hendershot, Liliana Wroblewska, H. Lily Zhu, Kimberly Ann Marquette, Kristine Svenson, Divya Mathur, Fernando Narciandi, Yan Liu, Weili Duan, Edward R. Lavallie, Alison Betts, Rosemary Lawrence-Henderson, Chang Chew Shun, Adam Root, Maya Arai, Madan Katragadda, Amy King, Amy Tam, Jatin Narula, Jason Wade, Kerry Kelleher, Lioudmila Tchistiakova, Lidia Mosyak, Alfredo Darmanin Sheehan, Han Yang, Yan Zhang, James R. Apgar, Edward Rosfjord, Laird Bloom, Caryl L. Meade, Matthew McKenna
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
We report here the discovery and optimization of a novel T cell retargeting anti-GUCY2C x anti-CD3ε bispecific antibody for the treatment of solid tumors. Using a combination of hybridoma, phage display and rational design protein engineering, we ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c6dd5658cfd24d66b5b31b6d32bf8c
https://pubmed.ncbi.nlm.nih.gov/33459147
https://pubmed.ncbi.nlm.nih.gov/33459147
Autor:
Cummins, Emma, Luxenberg, Deborah P., McAleese, Fionnuala, Widom, Angela, Fennell, Brian J., Darmanin-Sheehan, Alfredo, Whitters, Matthew J., Bloom, Laird, Gill, Davinder, Cunningham, Orla
Publikováno v:
In Journal of Immunological Methods 2008 339(1):38-46
Autor:
Marina Kovaleva, Kenneth Saunders, Caroline J. Barelle, Matthew J. Whitters, Jiquan Zhang, Deborah Luxenberg, John Steven, Emma Cummins, Miguel F. Carvalho, Alfredo Darmanin-Sheehan, Ronan O’Dwyer
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research
Journal of Immunology Research
Lymphocyte costimulation plays a central role in immunology, inflammation, and immunotherapy. The inducible T cell costimulator (ICOS) is expressed on T cells following peptide: MHC engagement with CD28 costimulation. The interaction of ICOS with its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b3534a19422f7eef7c47e6912dc79c
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b
https://doaj.org/article/2040fb960ade4e4a81c4768f6494230b
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