Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Darlynne A, Devenny"'
Autor:
Matthew D. Zammit, Darlynne A. Devenny, Charles M. Laymon, William E. Klunk, Brianna Piro-Gambetti, Dana L. Tudorascu, Sigan L. Hartley, Annie Cohen, Bradley T. Christian, Shahid Zaman, Benjamin L. Handen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction There is a critical need to identify measures of cognitive functioning sensitive to early Alzheimer's disease (AD) pathophysiology in Down syndrome to advance clinical trial research in this at‐risk population. The objective of the stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c66ea51d1df741f2409d7f11d0731a
https://doaj.org/article/7e9aee3f603e4830a622701188593006
https://doaj.org/article/7e9aee3f603e4830a622701188593006
Autor:
Todd E. Barnhart, Darlynne A. Devenny, Chester A. Mathis, William E. Klunk, Patrick J. Lao, Julie C. Price, Annie Cohen, Charles K. Stone, Dana L. Tudorascu, Brian J. Lopresti, Sterling C. Johnson, Tobey J. Betthauser, Rameshwari V. Tumuluru, Sigan L. Hartley, Ben Handen, Iulia Mihaila, Dhanabalan Murali, Bradley T. Christian, Peter Bulova
Publikováno v:
Journal of Alzheimer's Disease. 61:631-644
Background The Down syndrome (DS) population is genetically predisposed to amyloid-β protein precursor overproduction and Alzheimer's disease (AD). Objective The temporal ordering and spatial association between amyloid-β, glucose metabolism, and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82d6d598d468984b59f2a119cafcf5d
https://doi.org/10.3233/jad-170720
https://doi.org/10.3233/jad-170720
Autor:
Sterling C. Johnson, Patrick J. Lao, Regina M. Hardison, Sigan L. Hartley, Benjamin L. Handen, Darlynne A. Devenny, Peter Bulova, William E. Klunk, Bradley T. Christian, Iulia Mihaila
Publikováno v:
Neurobiology of Aging. 58:68-76
Adults with Down syndrome (DS) have a high incidence of Alzheimer's disease (AD), providing a unique opportunity to explore the early, preclinical stages of AD neuropathology. We examined change in brain amyloid-β accumulation via the positron emiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd729c4b94671a6832b1e4aada6439e9
https://doi.org/10.1016/j.neurobiolaging.2017.05.019
https://doi.org/10.1016/j.neurobiolaging.2017.05.019
Autor:
Sterling C. Johnson, Patrick J. Lao, Benjamin L. Handen, Rameshwari V. Tumuluru, Sigan L. Hartley, Bradley T. Christian, Darlynne A. Devenny, Iulia Mihaila, Peter Bulova
Publikováno v:
Intellectual and Developmental Disabilities. 55:97-109
The present study examined leisure activity and its association with caregiver involvement (i.e., residence and time spent with primary caregiver) in 62 middle-aged and older adults with Down syndrome (aged 30–53 years). Findings indicated that mid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d27ad14481fb2bf287eb0a9e611ef3e
https://doi.org/10.1352/1934-9556-55.2.97
https://doi.org/10.1352/1934-9556-55.2.97
Autor:
Benjamin L. Handen, Patrick J. Lao, Brad T. Christian, Darlynne A. Devenny, Sigan L. Hartley, Sterling C. Johnson, Dana L. Tudorascu, Bill E. Klunk
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffd6b7f28107c2e8c8bca3b28e38a9ab
https://doi.org/10.1016/j.jalz.2018.06.2970
https://doi.org/10.1016/j.jalz.2018.06.2970
Autor:
Benjamin L. Handen, Dana L. Tudorascu, Bill E. Klunk, Brad T. Christian, Darlynne A. Devenny, Sigan L. Hartley
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b779d069e14a1b1f1d2c647f591e818e
https://doi.org/10.1016/j.jalz.2018.06.2971
https://doi.org/10.1016/j.jalz.2018.06.2971
Autor:
Sterling C. Johnson, Todd E. Barnhart, Annie Cohen, Marsha R. Mailick, Iulia Mihaila, Ansel T. Hillmer, Rameshwari V. Tumuluru, Regina M. Hardison, Darlynne A. Devenny, Benjamin L. Handen, Dhanabalan Murali, Bradley T. Christian, Andrew T. Higgins, William E. Klunk, Julie C. Price, Sigan L. Hartley, Tobey J. Betthauser, Chester A. Mathis, Peter Bulova, Patrick J. Lao
Publikováno v:
Alzheimer's & Dementia. 12:380-390
In Down syndrome (DS), the overproduction of amyloid precursor protein is hypothesized to predispose young adults to early expression of Alzheimer-like neuropathology.PET imaging with carbon 11-labeled Pittsburgh compound B examined the pattern of am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc59093e46e010b72bcf7fdd63c9b01
https://doi.org/10.1016/j.jalz.2015.05.013
https://doi.org/10.1016/j.jalz.2015.05.013
Publikováno v:
Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities ISBN: 9783319617190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61045f0d15a9de84e7d6fe98c52f7218
https://doi.org/10.1007/978-3-319-61720-6_9
https://doi.org/10.1007/978-3-319-61720-6_9
Autor:
Sterling C. Johnson, Benjamin L. Handen, Sigan L. Hartley, Rameshwari V. Tumuluru, Tobey J. Betthauser, Darlynne A. Devenny, Chester A. Mathis, Brad T. Christian, Peter Bulova, Todd E. Barnhart, Ann D. Cohen, Patrick J. Lao, Dhanabalan Murali, Dana L. Tudorascu, Bill E. Klunk, Julie C. Price
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5804f6d5ea81a8d116d8c36782d7fb2a
https://doi.org/10.1016/j.jalz.2017.07.154
https://doi.org/10.1016/j.jalz.2017.07.154
Autor:
William E. Klunk, Dhanabalan Murali, Dana L. Tudorascu, Chester A. Mathis, Sigan L. Hartley, Sterling C. Johnson, Iulia Mihaila, Rameshwari V. Tumuluru, Todd E. Barnhart, Tobey J. Betthauser, Brian J. Lopresti, Marsha R. Mailick, Julie C. Price, Annie Cohen, Ben Handen, Peter Bulova, Bradley T. Christian, Patrick J. Lao, Darlynne A. Devenny, Charles K. Stone
Publikováno v:
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction Down syndrome (DS) arises from a triplication of chromosome 21, causing overproduction of the amyloid precursor protein and predisposes individuals to early Alzheimer's disease (AD). Methods Fifty-two nondemented adults with DS underwent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120e08885fc73e819fed1bc348af0fb3
https://pubmed.ncbi.nlm.nih.gov/28603769
https://pubmed.ncbi.nlm.nih.gov/28603769