Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Darline Garibay"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303110 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0200908.].
Externí odkaz:
https://doaj.org/article/bb6aada1f2d64b66aedfe5715efebbb7
Autor:
Mridusmita Saikia, Marlena M. Holter, Leanne R. Donahue, Isaac S. Lee, Qiaonan C. Zheng, Journey L. Wise, Jenna E. Todero, Daryl J. Phuong, Darline Garibay, Reilly Coch, Kyle W. Sloop, Adolfo Garcia-Ocana, Charles G. Danko, Bethany P. Cummings
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that potentiates glucose-stimulated insulin secretion. GLP-1 is classically produced by gut L cells; however, under certain circumstances α cells can express the prohormone convertase required f
Externí odkaz:
https://doaj.org/article/d8231da5c1ae478aaa15444e8576fb6f
Autor:
Mitchell Bayne, Alexandra Alvarsson, Kavya Devarakonda, Rosemary Li, Maria Jimenez-Gonzalez, Darline Garibay, Kaetlyn Conner, Merina Varghese, Madhavika N. Serasinghe, Jerry E. Chipuk, Patrick R. Hof, Sarah A. Stanley
Publikováno v:
JCI Insight, Vol 5, Iss 21 (2020)
Hypoglycemia is a frequent complication of diabetes, limiting therapy and increasing morbidity and mortality. With recurrent hypoglycemia, the counterregulatory response (CRR) to decreased blood glucose is blunted, resulting in hypoglycemia-associate
Externí odkaz:
https://doaj.org/article/23aab8c66b19432ca7e406bd9e534a7b
Autor:
Darline Garibay, Jon Lou, Seon A. Lee, Karolina E. Zaborska, Margot H. Weissman, Erica Sloma, Leanne Donahue, Andrew D. Miller, Andrew C. White, M. Dodson Michael, Kyle W. Sloop, Bethany P. Cummings
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 967-973 (2018)
Summary: Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by
Externí odkaz:
https://doaj.org/article/940bc9769f4046a8a710f3ef5f3a7948
Autor:
Anne K. McGavigan, Zachariah M. Henseler, Darline Garibay, Scott D. Butler, Sisitha Jayasinghe, Ruth E. Ley, Robin L. Davisson, Bethany P. Cummings
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 3, Pp 235-243 (2017)
Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes remarkable improvements in cardiometabolic health, including hypertension remission. However, the mechanisms responsible remain undefined and poorly studied. Therefore, we developed
Externí odkaz:
https://doaj.org/article/481678142d494caeac5fa493991c6bc7
Autor:
Michael J. Shanahan, Praveen Sethupathy, David C. Montrose, Darline Garibay, Karolina E. Zaborska, Katie M. Kelly, Andrew J. Dannenberg, Qiaonan Zheng, Bethany P. Cummings, Andrew D. Miller
Publikováno v:
Obes Surg
BACKGROUND AND AIMS: Bariatric surgery, such as vertical sleeve gastrectomy (VSG), is the most effective long-term treatment for obesity. However, there are conflicting reports on the effect of bariatric surgery on inflammatory bowel disease (IBD). B
Autor:
Marlena M. Holter, Adolfo Garcia-Ocana, Mridusmita Saikia, Charles G. Danko, Bethany Cummings, Darline Garibay
Publikováno v:
Diabetes. 69
Glucagon-like peptide-1 (GLP-1) regulates islet function by enhancing glucose-stimulated insulin secretion (GSIS). We previously found that the beta cell GLP-1 receptor (GLP-1R) contributes to improvements in glucose regulation and islet function in
Publikováno v:
Diabetes. 69
One out of every 10 Americans has diabetes, increasing their risk of death by 50% and more than doubling their health care costs. Delineating how the brain regulates metabolism, including feeding behavior and glucose homeostasis, may shed light on ho
Autor:
Darline Garibay, Seon A. Lee, Erin K. Daugherity, Elizabeth S. Moore, Mridusmita Saikia, Robert S. Weiss, Paul Cohen, Marlena M. Holter, Kathleen Kelly, Anne K. McGavigan, Lily Ngyuen, Bethany P. Cummings
Publikováno v:
FASEB J
P53 has been implicated in the pathogenesis of obesity and diabetes; however, the mechanisms and tissue sites of action are incompletely defined. Therefore, we investigated the role of hepatocyte p53 in metabolic homeostasis using a hepatocyte-specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32e0107bd7f4f90b5acf34d7b023655
https://europepmc.org/articles/PMC8884714/
https://europepmc.org/articles/PMC8884714/
Autor:
Kyle W. Sloop, M. Dodson Michael, Leanne R. Donahue, Karolina E. Zaborska, Darline Garibay, Andrew C. White, Jon Lou, Bethany P. Cummings, Margot H. Weissman, Andrew D. Miller, Seon A. Lee, Erica A. Sloma
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 967-973 (2018)
Cell reports
Cell reports
SUMMARY Bariatric surgery, such as vertical sleeve gastrectomy (VSG), causes high rates of type 2 diabetes remission and remarkable increases in postprandial glucagon-like peptide-1 (GLP-1) secretion. GLP-1 plays a critical role in islet function by