Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Darlene LaBonte"'
Autor:
Wenzhe Liu, Bruce Weaver, Xiangyu Liu, Jason Parent, Haijun Tian, Langzhou Song, Ge Liu, Youngsun Kim, Lynda Tussey, Hong Li, Lihua Duan, Linda Travalent, David W.C. Beasley, Robert Putnak, Lucia Reiserova, Darlene Labonte, John Misczak, Devin Wigington
Publikováno v:
Clinical and vaccine immunology : CVI. 22(5)
The envelope (E) protein of flaviviruses includes three domains, EI, EII, and EIII, and is the major protective antigen. Because EIII is rich in type-specific and subcomplex-specific neutralizing epitopes and is easy to express, it is particularly at
Autor:
Bart Scherens, Ning Lan, Steeve Veronneau, Anna Astromoff, Matt Curtiss, Ronald W. Davis, Jeffrey N. Strathern, Marleen Voet, Johannes H. Hegemann, Ankuta Lucau-Danila, Petra Ross-Macdonald, Adam M. Deutschbauer, Françoise Foury, Greg Schimmack, Daniel D. Shoemaker, Karen Davis, Rhonda Bangham, Darlene LaBonte, Christopher J. Roberts, Zelek S. Herman, Patrick Flaherty, Stefano Campanaro, Patrice Menard, Michael Snyder, Teresa R. Ward, Adam P. Arkin, Howard Bussey, Linda Riles, Yonghong Yang, Grace Yen, Guri Giaever, K. D. Entian, Kexin Yu, Elaine M. Youngman, Sharon Sookhai-Mahadeo, Jef D. Boeke, Reginald Storms, Daniel F. Jaramillo, Giorgio Valle, José L. Revuelta, Sally Dow, Mark Johnston, Matthias Rose, Mohamed El Bakkoury, Deanna Gotte, Hong Liao, Elizabeth A. Winzeler, Brenda Shafer, Marc Lussier, Chuanyun Luo, Siew Loon Ooi, Peter Philippsen, Angela M. Chu, Guido Volckaert, Rong Mao, Peter Kötter, Keith Anderson, Ching Yun Wang, Julie Wilhelmy, Ulrich Güldener, Li Ni, Lucy Y. Liu, Mark Gerstein, David C. Lamb, Steven L. Kelly, Carla Connelly, Diane E. Kelly, Svenja Hempel, Rocío Benito, David J. Garfinkel, Bruno André, Hong Liang, Sophie Brachat
Publikováno v:
Nature. 418:387-391
Determining the effect of gene deletion is a fundamental approach to understanding gene function. Conventional genetic screens exhibit biases, and genes contributing to a phenotype are often missed. We systematically constructed a nearly complete col