Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Darlene K. Satonin"'
Incorporating dried blood spot LC–MS/MS analysis for clinical development of a novel oncolytic agent
Autor:
Chris A. Schmalz, Sophie Callies, Lisa B Lee, Darlene K. Satonin, Enaksha R Wickremsinhe, Elizabeth Smith Labell
Publikováno v:
Bioanalysis. 10:341-356
Aim: Design and execution of a dried blood spot (DBS-LC–MS/MS) assay for pharmacokinetic analyses in oncology patients. Results & discussion: The methodology was validated to collect and store DBS samples from multiple clinical sites, and analyze b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214b3a845f47416ece1954883cae203a
https://doi.org/10.4155/bio-2017-0231
https://doi.org/10.4155/bio-2017-0231
Publikováno v:
The Journal of Sexual Medicine. 13:187-193
Introduction Testosterone 2% solution (Axiron) applied to armpit(s) is used for replacement therapy in men with a deficiency of endogenous testosterone. Aim To determine the amount of testosterone on subjects' T-shirts 12 hours after applying testost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174a79744c0937253ed988973eeb0579
https://doi.org/10.1016/j.jsxm.2015.12.007
https://doi.org/10.1016/j.jsxm.2015.12.007
Autor:
Boris A, Czeskis, Darlene K, Satonin
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 60(2)
The synthesis of the radiolabeled glucagon receptor antagonist 1-[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58ce44a9487984d63aa64a2921028736
https://pubmed.ncbi.nlm.nih.gov/27910129
https://pubmed.ncbi.nlm.nih.gov/27910129
Publikováno v:
Journal of Chromatography B. 852:582-589
A sensitive bioanalytical method for the measurement of two major circulating metabolites of duloxetine [4-hydroxy duloxetine glucuronide (LY550408) and 5-hydroxy-6-methoxy duloxetine sulfate (LY581920)] in plasma is reported. This method produced ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6772f9e315147ef5f07fc4ed25df9fe2
https://doi.org/10.1016/j.jchromb.2007.02.025
https://doi.org/10.1016/j.jchromb.2007.02.025
Publikováno v:
The journal of sexual medicine. 11(11)
Introduction Testosterone 2% solution is applied to axillae and is indicated for testosterone replacement therapy in males deficient in endogenous testosterone. Aim This open‐label crossover study evaluated the effect of deodorant/antiperspirant us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1035929962f034eab2502eb82124b2ce
https://pubmed.ncbi.nlm.nih.gov/25617293
https://pubmed.ncbi.nlm.nih.gov/25617293
Publikováno v:
Journal of Pharmaceutical Sciences. 73:1758-1763
The bioavailability and pharmacokinetic behavior of 10 mg/kg of [ 14 C]probucol in an oil-water emulsion was determined after oral and intravenous administration to rats. The bioavailability of the oral formulation was ~6%. For the first 12-h interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bc66f6bd9f06f8e8ee9953ef75514c
https://doi.org/10.1002/jps.2600731225
https://doi.org/10.1002/jps.2600731225
Publikováno v:
Biological Mass Spectrometry. 14:325-330
The structure elucidation of drug metabolites directly from urine by tandem mass spectrometry (MS/MS) for a new bronchodilator is described. When urine samples from human subjects dosed with 400 mg of MDL 257 were examined by MS/MS, three major urina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf2221742965381038dbf665feb7985
https://doi.org/10.1002/bms.1200140705
https://doi.org/10.1002/bms.1200140705
Autor:
John E. Coutant, Darlene K. Satonin
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 380:401-406
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3713cef5dce701fe74c11280c9060688
https://doi.org/10.1016/s0378-4347(00)83670-1
https://doi.org/10.1016/s0378-4347(00)83670-1