Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Darlene A. Hastings-Smith"'
Autor:
Darlene A. Hastings-Smith, Jonathan B. Ward, Judah I. Rosenblatt, Sherif Z. Abdel-Rahman, Marinel M. Ammenheuser, William E. Bechtold
Publikováno v:
Environmental Health Perspectives
1,3-Butadiene (BD), which is used to make styrene-butadiene rubber, is a potent carcinogen in mice and a probable carcinogen, associated with leukemia, in humans. We have previously used HPRT mutation as a biomarker to evaluate exposures to BD in a m
Autor:
Jonathan B. Ward, R. Stephen Lloyd, Edward M. Postlethwait, Marinel M. Ammenheuser, Sherif Z. Abdel-Rahman, James J. Salazar, Jeffrey K. Wickliffe, Darlene A. Hastings-Smith
Publikováno v:
Environmental and molecular mutagenesis. 42(2)
The specific role that polymorphisms in xenobiotic metabolizing enzymes play in modulating sensitivity to 1,3-butadiene (BD) genotoxicity has been relatively unexplored. The enzyme microsomal epoxide hydrolase (mEH) is important in detoxifying the mu
Autor:
Jeffrey K. Wickliffe, Marinel M. Ammenheuser, James J. Salazar, Sherif Z. Abdel-Rahman, Darlene A. Hastings-Smith, Edward M. Postlethwait, R. Stephen Lloyd, Jonathan B. Ward
Publikováno v:
Environmental & Molecular Mutagenesis; Aug2003, Vol. 42 Issue 2, p106-110, 5p