Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Darko Libl"'
Autor:
Henrik Schinke, Min Pan, Merve Akyol, Jiefu Zhou, Enxian Shi, Gisela Kranz, Darko Libl, Tanja Quadt, Florian Simon, Martin Canis, Philipp Baumeister, Olivier Gires
Publikováno v:
Molecular Oncology, Vol 16, Iss 2, Pp 347-367 (2022)
Partial epithelial‐to‐mesenchymal transition (pEMT) contributes to cellular heterogeneity that is associated with nodal metastases and unfavorable clinical parameters in head and neck squamous cell carcinomas (HNSCCs). We developed a single‐cel
Externí odkaz:
https://doaj.org/article/fc274dc569f8458e8023a0c68c5014e2
Autor:
Min Pan, Henrik Schinke, Elke Luxenburger, Gisela Kranz, Julius Shakhtour, Darko Libl, Yuanchi Huang, Aljaž Gaber, Miha Pavšič, Brigita Lenarčič, Julia Kitz, Mark Jakob, Sabina Schwenk-Zieger, Martin Canis, Julia Hess, Kristian Unger, Philipp Baumeister, Olivier Gires
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2006624 (2018)
Head and neck squamous cell carcinomas (HNSCCs) are characterized by outstanding molecular heterogeneity that results in severe therapy resistance and poor clinical outcome. Inter- and intratumoral heterogeneity in epithelial-mesenchymal transition (
Externí odkaz:
https://doaj.org/article/f50b19f0c6f44b07ae3d77277cf46991
Autor:
Merve Akyol, Philipp Baumeister, Tanja Quadt, Enxian Shi, Gisela Kranz, Darko Libl, Florian Simon, Min Pan, Olivier Gires, Henrik Schinke, Jiefu Zhou, Martin Canis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38470d2c0d6badbafa390604a9e076ce
https://doi.org/10.1002/1878-0261.13075/v2/response1
https://doi.org/10.1002/1878-0261.13075/v2/response1
Autor:
Merve Akyol, Min Pan, Gisela Kranz, Philipp Baumeister, Florian Simon, Darko Libl, Martin Canis, Henrik Schinke, Olivier Gires, Jiefu Zhou
Therapy resistance leading to local recurrence and metastases remains highly problematic in head and neck squamous cell carcinomas (HNSCC). Single cell RNA-sequencing defined a partial epithelial-to-mesenchymal transition (p-EMT) signature associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d9a722f0e336ce6fbc1e6fa32cb736
https://doi.org/10.1101/2020.10.20.346692
https://doi.org/10.1101/2020.10.20.346692
Autor:
Olivier Gires, Hongxia Wang, Xiao Liu, Bernd Uhl, Darko Libl, Daisy D. Wang, H. Braselmann, Yuanchi Huang, Juncheng Dai, Cornelia Voigt, Junjian Li, Javier Suárez, Bruno L. Cadilha, Min Pan, Isabella Zagorski, Anna Krandick, Christoph A. Reichel, Sebastian Niedermeyer, Sebastian Kobold, Sibo Zhu, Daria Briukhovetska, Peter Lin, Gisela Kranz, Zhe Huang, Horst Zitzelsberger, Anamarija Markota
Publikováno v:
Science Advances
Sci. Adv. 5:eaav4275 (2019)
Sci. Adv. 5:eaav4275 (2019)
Association of epithelial-mesenchymal transition with the metastatic potential of disseminated cells in breast cancer was studied.
Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions of EMT heterogeneity to di
Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions of EMT heterogeneity to di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d58df3d414370a1c633d842d321b6b
Autor:
Gisela Kranz, Stefanie M. Hauck, Brigitte Mack, Sannia Sarrach, Sebastian Gille, Juliane Merl-Pham, Min Pan, Antonio Scialdone, Sebastian Niedermeyer, Laura Elisabeth Fischer, Irmela Jeremias, Matthias Hachmeister, Yuanchi Huang, Darko Libl, Matthias Kieslinger, Olivier Gires, Elisa Paoluzzi Tomada
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Sci. Rep. 8:1801 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)
Sci. Rep. 8:1801 (2018)
Epithelial cell adhesion molecule EpCAM is expressed in pluripotent embryonic stem cells (ESC) in vitro, but is repressed in differentiated cells, except epithelia and carcinomas. Molecular functions of EpCAM, possibly imposing such repression, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b2a64b23b6af58d979217a08421bf4
http://europepmc.org/articles/PMC5789065
http://europepmc.org/articles/PMC5789065
Autor:
Brigitte Mack, Veronika Volgger, Darko Libl, Anna S. Englhard, Olivier Gires, Christian S. Betz, Herbert Stepp, Alexander Palaras
Publikováno v:
Journal of biophotonics. 10(10)
Intraoperative detection of residual malignant cells at tumor margins following excision of primary tumors could help improving surgery and thus patients' outcome. The feasibility of the tumor antigens epidermal growth factor receptor (EGF-R) and epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadb115ae3735f618b5cc4e6d93c8032
https://pubmed.ncbi.nlm.nih.gov/28106950
https://pubmed.ncbi.nlm.nih.gov/28106950
Autor:
Julia Hess, Brigita Lenarčič, Kristian Unger, Gisela Kranz, Yuanchi Huang, Julia Kitz, Sabina Schwenk-Zieger, Julius Shakhtour, Min Pan, Martin Canis, Mark Jakob, Aljaž Gaber, Olivier Gires, Elke Luxenburger, Henrik Schinke, Miha Pavšič, Darko Libl, Philipp Baumeister
Publikováno v:
PLoS Biology
PLoS Biology, Vol 16, Iss 9, p e2006624 (2018)
PLoS Biol. 16:e2006624 (2018)
PLoS Biology, Vol 16, Iss 9, p e2006624 (2018)
PLoS Biol. 16:e2006624 (2018)
Head and neck squamous cell carcinomas (HNSCCs) are characterized by outstanding molecular heterogeneity that results in severe therapy resistance and poor clinical outcome. Inter- and intratumoral heterogeneity in epithelial-mesenchymal transition (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2a653c873721223da242b90537020b0
https://doi.org/10.1371/journal.pbio.2006624
https://doi.org/10.1371/journal.pbio.2006624