Výsledky vyhledávání - "Darkhan Tursynkhan"

Inhibition of Cancer Cell Proliferation by Carbon Dots Derived from Date Pits at Low-Dose

Autor: Mannix P. Balanay, Haiyan Fan, Kunjie Wang, Qing Yang, Yerkebulan Yesbolatov, Darkhan Tursynkhan, Aishabibi Kassymbek, Mohamed Bouhrara, Yingqiu Xie, Olena Filchakova

Publikováno v: ChemistrySelect. 2:4079-4083

Water-soluble fluorescent carbon dots (C-dots) were synthesized through hydrothermal process using date pits pre-treated with phosphoric acid as a carbon source. Transmission electron microscopy showed that the C-dots have an average particle size of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a48c42511b8dfbfeee2892ad59be5f3
https://doi.org/10.1002/slct.201700575

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Dysregulation of YAP by ARF Stimulated with Tea-derived Carbon Nanodots

Autor: Aisulu Maipas, Yingqiu Xie, Jinhong Feng, Darkhan Tursynkhan, Sholpan Kauanova, Zhenbang Chen, Mirat Karibayev, Qinglei Sun, Jiang Lu, Xiao Wang, Aishabibi Kassymbek, Mannix P. Balanay, Qing Yang, Korlan Duisenova, Haiyan Fan, Ayan Nurkesh, Limara Manarbek

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)

YAP is a downstream nuclear transcription factor of Hippo pathway which plays an essential role in development, cell growth, organ size and homeostasis. It was previously identified that elevation of YAP in genomics of genetic engineered mouse (GEM)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46290b7c319f0917c776801cb37cbd55
http://europepmc.org/articles/PMC5707370

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Abstract 5498: Natural product-derived carbon nanodots overcome drug resistance through regulation of Hippo pathway effectors

Autor: Aisulu Maipas, Tleubek Yeleusizov, Yan Zhang, Haiyan Fan, Bakhyt T. Matkarimov, Si-Pian Li, Mannix P. Balanay, Qing Yang, Yingqiu Xie, Zhenbang Chen, Xiaoling Wan, Ayan Nurkesh, Lixia Miao, Limara Manarbek, Darkhan Tursynkhan

Publikováno v: Cancer Research. 78:5498-5498

The yes-associated protein 1 (YAP) is a nuclear downstream effector of Hippo pathway that plays a critical role in various cancers. Literature shows that, in addition to nucleus, YAP also localizes in cytosol and membrane of cells. We and our collabo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::568f2abfcbcc5f5dd514fb64f5e55f42
https://doi.org/10.1158/1538-7445.am2018-5498

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