Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Darjus F Tschaharganeh"'
Autor:
Changyu Zhu, Yadira M Soto-Feliciano, John P Morris, Chun-Hao Huang, Richard P Koche, Yu-jui Ho, Ana Banito, Chun-Wei Chen, Aditya Shroff, Sha Tian, Geulah Livshits, Chi-Chao Chen, Myles Fennell, Scott A Armstrong, C David Allis, Darjus F Tschaharganeh, Scott W Lowe
Publikováno v:
eLife, Vol 12 (2023)
Mutations in genes encoding components of chromatin modifying and remodeling complexes are among the most frequently observed somatic events in human cancers. For example, missense and nonsense mutations targeting the mixed lineage leukemia family me
Externí odkaz:
https://doaj.org/article/00891c2adbc24612b3cca84dd953d236
Autor:
Stephan Krieg, Thomas Rohde, Tobias Rausch, Luise Butthof, Lena Wendler-Link, Christoph Eckert, Kai Breuhahn, Bruno Galy, Jan Korbel, Maximilian Billmann, Marco Breinig, Darjus F. Tschaharganeh
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Somatic copy number alterations are a hallmark of cancer that offer unique opportunities for therapeutic exploitation. Here, we focused on the identification of specific vulnerabilities for tumors harboring chromosome 8p deletions
Externí odkaz:
https://doaj.org/article/d7c5dfffb2304419945cd7a2bce10c8a
Autor:
Pierre Billon, Tarun S. Nambiar, Samuel B. Hayward, Maria P. Zafra, Emma M. Schatoff, Koichi Oshima, Andrew Dunbar, Marco Breinig, Young C. Park, Han S. Ryu, Darjus F. Tschaharganeh, Ross L. Levine, Richard Baer, Adolfo Ferrando, Lukas E. Dow, Alberto Ciccia
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3280-3295.e6 (2020)
Summary: Genome editing technologies have transformed our ability to engineer desired genomic changes within living systems. However, detecting precise genomic modifications often requires sophisticated, expensive, and time-consuming experimental app
Externí odkaz:
https://doaj.org/article/b762df76412f41f19bcbc386580b5456
Autor:
Scott W. Lowe, Christopher R. Vakoc, Agustin Chicas, Vishal Thapar, Myles Fennell, Chi-Chao Chen, Jessica E. Bolden, Ozlem Aksoy, Chun-Hao Huang, Darjus F. Tschaharganeh, Matthew Camiolo, Direna Alonso-Curbelo, Jae-Seok Roe, Ana Banito, Nilgun Tasdemir
Supplementary Figure S1. Senescence-activated SASP enhancers are marked by H3K4Me1 in proliferating IMR90 cells. Supplementary Figure S2. Reproducibility analyses of biological replicates for H3K27Ac and BRD4 ChIP-Seq. Supplementary Figure S3. Enhanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798e0f8cd40a7d950c1af92f4da5d540
https://doi.org/10.1158/2159-8290.22531508.v1
https://doi.org/10.1158/2159-8290.22531508.v1
Autor:
Scott W. Lowe, Christopher R. Vakoc, Agustin Chicas, Vishal Thapar, Myles Fennell, Chi-Chao Chen, Jessica E. Bolden, Ozlem Aksoy, Chun-Hao Huang, Darjus F. Tschaharganeh, Matthew Camiolo, Direna Alonso-Curbelo, Jae-Seok Roe, Ana Banito, Nilgun Tasdemir
Co-culture of NK cells and P/shRen IMR90 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbb80042a6c8487c3efb555e5169eb7
https://doi.org/10.1158/2159-8290.22531490
https://doi.org/10.1158/2159-8290.22531490
Autor:
Scott W. Lowe, Christopher R. Vakoc, Agustin Chicas, Vishal Thapar, Myles Fennell, Chi-Chao Chen, Jessica E. Bolden, Ozlem Aksoy, Chun-Hao Huang, Darjus F. Tschaharganeh, Matthew Camiolo, Direna Alonso-Curbelo, Jae-Seok Roe, Ana Banito, Nilgun Tasdemir
Supplementary Methods, Figure Legends, References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e8592a7197ceec4698329b0b2a0017
https://doi.org/10.1158/2159-8290.22531505
https://doi.org/10.1158/2159-8290.22531505
Autor:
Scott W. Lowe, Christopher R. Vakoc, Agustin Chicas, Vishal Thapar, Myles Fennell, Chi-Chao Chen, Jessica E. Bolden, Ozlem Aksoy, Chun-Hao Huang, Darjus F. Tschaharganeh, Matthew Camiolo, Direna Alonso-Curbelo, Jae-Seok Roe, Ana Banito, Nilgun Tasdemir
Lists of senescence-activated and senescence-inactivated TEs and SEs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168b8af7ddabaf3297f8ba503c57ac62
https://doi.org/10.1158/2159-8290.22531502
https://doi.org/10.1158/2159-8290.22531502
Autor:
Kai Breuhahn, Franziska Matthäus, Peter Schirmacher, Darjus F. Tschaharganeh, Michael Meister, Thomas Muley, Norbert Gretz, Nikola S. Müller, Fabian J. Theis, Arne Warth, Carolina De La Torre, Jennifer Schmitt, Justo Lorenzo-Bermejo, Francisco J. Sánchez-Rivera, Steffen Sass, Adriana Pitea, Julian Gutekunst, Damian Stichel, Carsten Sticht, Marco Albrecht, Manuel Rodríguez-Paredes, Margarita González-Vallinas
Figure S1. Expression of 14q32 miRNAs in tumor samples from lung adenocarcinoma patients according to EGFR, KRAS and TP53 mutation status. Figure S2. Methylation analysis of imprinting control regions of the 14q32 cluster in lung adenocarcinoma patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d603c61d4643be46ad7da1f68d0c3790
https://doi.org/10.1158/1541-7786.22517488.v1
https://doi.org/10.1158/1541-7786.22517488.v1
Autor:
Kai Breuhahn, Franziska Matthäus, Peter Schirmacher, Darjus F. Tschaharganeh, Michael Meister, Thomas Muley, Norbert Gretz, Nikola S. Müller, Fabian J. Theis, Arne Warth, Carolina De La Torre, Jennifer Schmitt, Justo Lorenzo-Bermejo, Francisco J. Sánchez-Rivera, Steffen Sass, Adriana Pitea, Julian Gutekunst, Damian Stichel, Carsten Sticht, Marco Albrecht, Manuel Rodríguez-Paredes, Margarita González-Vallinas
Supplementary Data - Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbdc781b209deb02e5e3ff28836efb6
https://doi.org/10.1158/1541-7786.22517491.v1
https://doi.org/10.1158/1541-7786.22517491.v1
Autor:
Kai Breuhahn, Franziska Matthäus, Peter Schirmacher, Darjus F. Tschaharganeh, Michael Meister, Thomas Muley, Norbert Gretz, Nikola S. Müller, Fabian J. Theis, Arne Warth, Carolina De La Torre, Jennifer Schmitt, Justo Lorenzo-Bermejo, Francisco J. Sánchez-Rivera, Steffen Sass, Adriana Pitea, Julian Gutekunst, Damian Stichel, Carsten Sticht, Marco Albrecht, Manuel Rodríguez-Paredes, Margarita González-Vallinas
Supplementary Data - Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03073e09ddb0ef61470d46b6a80795c5
https://doi.org/10.1158/1541-7786.22517494
https://doi.org/10.1158/1541-7786.22517494