Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Darja Koutova"'
Autor:
Martin Uher, Miloš Hroch, Rozálie Peřinová, Radim Havelek, Jana Křoustková, Martina Řezáčová, Darina Muthná, Darja Koutová, Jiří Kuneš, Lucie Cahlíková
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 5, Pp 103746- (2022)
In this study, a new series of aliphatic, cyclic, and heterocyclic derivatives of haemanthamine was designed and synthesized to enhance its inhibitory effect on the proliferation and viability of cancer cells. A library of haemanthamine derivatives w
Externí odkaz:
https://doaj.org/article/0b444150ae55421aa2d68d3af1eaeb57
Autor:
Aneta Ritomská, Darja Koutova, Jana Křoustková, Karel Královec, Darina Muthná, Jiří Kuneš, Lucie Nováková, Radim Havelek, Lucie Cahlíková
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 8, Pp 101684- (2023)
Ambelline, an alkaloid from the Amaryllidaceae family with a crinane-type skeleton, has not yet demonstrated any outstanding biological activity. However, its analogues prepared by derivatization of the C-11 hydroxyl group show different interesting
Externí odkaz:
https://doaj.org/article/a801666b7a734259b25a002e2f54f0aa
Autor:
Darja Koutova, Monika Kulhava, Radim Havelek, Martina Majorosova, Karel Královec, Klara Habartova, Anna Hošťálková, Lubomír Opletal, Lucie Cahlikova, Martina Řezáčová
Publikováno v:
Molecules, Vol 25, Iss 4, p 964 (2020)
Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L. (Berberidaceae) plant. The results of cytotoxicity screening 48 h post-treatment showed that bersavine considerably inhibits the proliferation and viability of
Externí odkaz:
https://doaj.org/article/887e44d3d56a45b19733abc35394203b
Autor:
Alzbeta Filipova, Jan Marek, Radim Havelek, Jaroslav Pejchal, Marcela Jelicova, Jana Cizkova, Martina Majorosova, Lubica Muckova, Tomas Kucera, Lukas Prchal, Miroslav Psotka, Natalie Zivna, Darja Koutova, Zuzana Sinkorova, Martina Rezacova, Ales Tichy
Publikováno v:
Molecules, Vol 25, Iss 3, p 532 (2020)
The increasing risk of radiation exposure underlines the need for novel radioprotective agents. Hence, a series of novel 1-(2-hydroxyethyl)piperazine derivatives were designed and synthesized. Some of the compounds protected human cells against radia
Externí odkaz:
https://doaj.org/article/8e047d5c8c22403da51ebf57d1ca52df
Autor:
Lucie Cahlíková, Latifah Al Shammari, Abdullah Al Mamun, Katerina Breiterova, Daniela Hulcova, Jana Marikova, Marcela Safratova, Darja Koutova, Radim Havelek, Martina Majorosova
Publikováno v:
Records of Natural Products, Vol 14, Iss 2, Pp 154-159 (2019)
Different species, hybrids and varieties of the genus Hippeastrum (Amaryllidaceae) are planted for ornamental purposes and at the same time they represent a rich source of interesting secondary metabolites called Amaryllidaceae alkaloids. These compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::ac07d63017f43619d7e73851d1750782
https://www.acgpubs.org/doc/20191126064606A9-148-RNP-1906-1302.pdf
https://www.acgpubs.org/doc/20191126064606A9-148-RNP-1906-1302.pdf
Autor:
Darja, Koutova, Monika, Kulhava, Radim, Havelek, Martina, Majorosova, Karel, Královec, Klara, Habartova, Anna, Hošťálková, Lubomír, Opletal, Lucie, Cahlikova, Martina, Řezáčová
Publikováno v:
Molecules, Vol 25, Iss 4, p 964 (2020)
Molecules
Molecules
Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L. (Berberidaceae) plant. The results of cytotoxicity screening 48 h post-treatment showed that bersavine considerably inhibits the proliferation and viability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::af79629547f41588855c3c93a7f74853
https://hdl.handle.net/10195/77494
https://hdl.handle.net/10195/77494
Autor:
Tumisang Edward Maseko, Eva Peterová, Moustafa Elkalaf, Darja Koutová, Jan Melek, Pavla Staňková, Veronika Špalková, Reem Matar, Halka Lotková, Zuzana Červinková, Otto Kučera
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1179 (2024)
Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins such as collagen I to promote cell adhesion. While studies h
Externí odkaz:
https://doaj.org/article/f49d5b3112a34a999a8e994a2eb89568
Autor:
Negar Maafi, Abdullah Al Mamun, Ondřej Janďourek, Jana Maříková, Kateřina Breiterová, Adéla Diepoltová, Klára Konečná, Anna Hošťálková, Daniela Hulcová, Jiří Kuneš, Eliška Kohelová, Darja Koutová, Marcela Šafratová, Lucie Nováková, Lucie Cahlíková
Publikováno v:
Molecules, Vol 26, Iss 19, p 6023 (2021)
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year. Nine Amaryllidaceae alkaloid
Externí odkaz:
https://doaj.org/article/4050f680840c4d96813412ba50368aac
Autor:
Darja Koutová, Negar Maafi, Radim Havelek, Lubomír Opletal, Gerald Blunden, Martina Řezáčová, Lucie Cahlíková
Publikováno v:
Molecules, Vol 25, Iss 10, p 2337 (2020)
Plants of the Amaryllidaceae family are promising therapeutic tools for human diseases and have been used as alternative medicines. The specific secondary metabolites of this plant family, called Amaryllidaceae alkaloids (AA), have attracted consider
Externí odkaz:
https://doaj.org/article/d1fb33f6b83a4c6695707dc8b6583549
Autor:
Kateřina Breiterová, Darja Koutová, Jana Maříková, Radim Havelek, Jiří Kuneš, Martina Majorošová, Lubomír Opletal, Anna Hošťálková, Jaroslav Jenčo, Martina Řezáčová, Lucie Cahlíková
Publikováno v:
Plants, Vol 9, Iss 2, p 137 (2020)
In this detailed phytochemical study of Narcissus cv. Professor Einstein, we isolated 23 previously known Amaryllidaceae alkaloids (1−23) of several structural types and one previously undescribed alkaloid, 7-oxonorpluviine. The chemical structures
Externí odkaz:
https://doaj.org/article/3a90bdd9d77f48cab42e08108628f5de