Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Darja Andreev"'
Autor:
Darja Andreev, Katerina Kachler, Mengdan Liu, Zhu Chen, Brenda Krishnacoumar, Mark Ringer, Silke Frey, Gerhard Krönke, David Voehringer, Georg Schett, Aline Bozec
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow. The absence of eosinophils
Externí odkaz:
https://doaj.org/article/5da2f219e2984371a8d14992bdd17d44
Autor:
Xianyi Meng, Zhen Lin, Shan Cao, Iga Janowska, Koshiro Sonomoto, Darja Andreev, Knab Katharina, Jinming Wen, Karl Xaver Knaup, Michael Sean Wiesener, Gerhard Krönke, Marta Rizzi, Georg Schett, Aline Bozec
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified mice and high-t
Externí odkaz:
https://doaj.org/article/3dfcd33747ef418ba671e3b6b8d7e69e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Introduction: Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the immune status for prognostic
Externí odkaz:
https://doaj.org/article/fbe90a244a8f4b7cb46536e21bc1bcc4
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Katrin Peckert-Maier, Andreas B. Wild, Elisabeth Zinser, Petra Mühl-Zürbes, Evan Jones, Susanne Adam, Silke Frey, Maximilian Fuchs, Meik Kunz, Tobias Bäuerle, Lisa Nagel, Georg Schett, Aline Bozec, Alexander Steinkasserer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and OC-Stamp were strongly reduced, while Foxp
Externí odkaz:
https://doaj.org/article/576ad5b73c124cb0990703d4d392cc97
Autor:
Zhen Lin, Xianyi Meng, Jinming Wen, José María Corral, Darja Andreev, Katerina Kachler, Georg Schett, Xiaoxiang Chen, Aline Bozec
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundHuman malignant melanoma is a highly aggressive, heterogeneous and drug-resistant cancer. Due to a high number of clones, harboring various mutations that affect key pathways, there is an exceptional level of phenotypic variation and intrat
Externí odkaz:
https://doaj.org/article/6f9ffd91faac4b5fab99af39e5804a8f
Autor:
Xianyi Meng, Zhen Lin, Iga Janowska, Shan Cao, Koshiro Sonomoto, Darja Andreev, Karl Xaver Knaup, Michael Sean Wiesener, Marta Rizzi, Georg Schett, Aline Bozec
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100310- (2020)
Externí odkaz:
https://doaj.org/article/eda6c8f8c2774b65aa3ea112a868d8ab
Autor:
Yasunori Omata, Michael Frech, Tatjana Primbs, Sébastien Lucas, Darja Andreev, Carina Scholtysek, Kerstin Sarter, Markus Kindermann, Nataliya Yeremenko, Dominique L. Baeten, Nico Andreas, Thomas Kamradt, Aline Bozec, Andreas Ramming, Gerhard Krönke, Stefan Wirtz, Georg Schett, Mario M. Zaiss
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 169-180 (2018)
Summary: Group 2 innate lymphoid cells (ILC2s) were detected in the peripheral blood and the joints of rheumatoid arthritis (RA) patients, serum-induced arthritis (SIA), and collagen-induced arthritis (CIA) using flow cytometry. Circulating ILC2s wer
Externí odkaz:
https://doaj.org/article/887aecb0527247c7819b597695f65869
Autor:
Dmytro Royzman, Darja Andreev, Lena Stich, Manfred Rauh, Tobias Bäuerle, Stephan Ellmann, Louis Boon, Markus Kindermann, Katrin Peckert, Aline Bozec, Georg Schett, Alexander Steinkasserer, Elisabeth Zinser
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Interference with autoimmune-mediated cytokine production is a key yet poorly developed approach to treat autoimmune and inflammatory diseases such as rheumatoid arthritis. Herein, we show that soluble CD83 (sCD83) enhances the resolution of autoimmu
Externí odkaz:
https://doaj.org/article/aad69cc2db014653827f30160fbd18d1
Autor:
Zhu Chen, Darja Andreev, Katharina Oeser, Branislav Krljanac, Axel Hueber, Arnd Kleyer, David Voehringer, Georg Schett, Aline Bozec
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Type 2 immune responses are viewed as opposites of Type 1 and 17 responses. Here the authors show that activation of Type 2 immunity by helminth infection counteracts the development of inflammatory arthritis, a type 17-mediated pathology, via IL-4/I
Externí odkaz:
https://doaj.org/article/14215b3bc91c4884a29bc4560ad6b232
A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens
Autor:
Lidia Almenara-Fuentes, Silvia Rodriguez-Fernandez, Estela Rosell-Mases, Katerina Kachler, Axel You, Miriam Salvado, Darja Andreev, Ulrike Steffen, Holger Bang, Aline Bozec, Georg Schett, Rozen Le Panse, Joan Verdaguer, Marti Dalmases, Silvia Rodriguez-Vidal, Bruna Barneda-Zahonero, Marta Vives-Pi
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine
Nanomedicine: Nanotechnology, Biology and Medicine, 2022, pp.102635. ⟨10.1016/j.nano.2022.102635⟩
Nanomedicine: Nanotechnology, Biology and Medicine, 2022, pp.102635. ⟨10.1016/j.nano.2022.102635⟩
International audience; Autoimmune diseases (AIDs) are caused by the loss of self-tolerance and destruction of tissues by the host's immune system. Several antigen-specific immunotherapies, focused on arresting the autoimmune attack, have been tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5595d767c57514caf41ac79417c0eb
https://hal.science/hal-03885962
https://hal.science/hal-03885962
