Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Dariusz W Kowalczyk"'
Autor:
Eliza P. Kwiatkowska-Borowczyk, Anna Kozłowska, Klaudia Maruszak, Luiza Kańczuga-Koda, Mariusz Koda, Monika Dajnowiec, Andrzej Mackiewicz, Dariusz W. Kowalczyk
Publikováno v:
Journal of Medical Science, Vol 83, Iss 1 (2014)
Donor lymphocyte infusion is used to increase the graft versus tumor (GVT) effect after allogeneic hematopoietic cell transplant. The limited spectrum of activity and high risk of graft versus host disease (GVHD) remain major limitations of this appr
Externí odkaz:
https://doaj.org/article/b80fb29c5d124739ac7221d550ef3a20
Autor:
Maria Chrzanowska, Jacek Wachowiak, Dawid Szpecht, Joanna Sobiak, Dariusz W. Kowalczyk, Urszula Kazimierczak, Mariusz Wysocki, Jan Styczyński
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis
The impact of etoposide (VP-16) plasma concentrations on the day of allogeneic hematopoietic stem cell transplantation (allo-HSCT) on leukemia-free survival in children with acute lymphoblastic leukemia (ALL) was studied. In addition, the in vitro ef
Autor:
Dieter Rosskopf, Heyo K. Kroemer, Christoph A. Ritter, Dariusz W. Kowalczyk, Tobias Hübner, Jérôme Guitton, Markus M. Lerch, Christian Rimmbach, Gabriele Jedlitschky, Matthias Sendler, Steffen Mews, Praveen K. Nambaru, Léa Payen, Julia Mayerle, Frank Ulrich Weiss, Kathleen Köck, Markus Grube
Publikováno v:
Drug Metabolism and Disposition. 39:132-139
Pancreatic adenocarcinoma is one of the malignancies that is highly resistant to therapy and among the leading causes of cancer-related death. Several factors may influence pancreatic cancer resistance, and expression of ATP-binding cassette transpor
Publikováno v:
Acta Biochimica Polonica. 53:361-369
We have constructed and expressed recombinant chimeric soluble TGF-beta type II receptor fused with the Fc portion of human IgG1 (sTbetaRII-Fc) in NS0 mouse myeloma cells and isolated cell lines constitutively secreting very high levels of biological
Publikováno v:
Acta Biochimica Polonica. 50:613-624
The ability of various cytokines to hamper tumor growth or to induce anti-tumor immune response has resulted in their study as antitumor agents in gene therapy approaches. In this review we will concentrate on the costimulation of antitumor immune re
Autor:
Dariusz W Kowalczyk
Publikováno v:
Acta Biochimica Polonica. 49:295-302
This article reviews the evidence for the danger model in the context of immune response to tumors and the insufficiency of the immune system to eliminate tumor growth. Despite their potential immunogenicity tumors do not induce significant immune re
Autor:
Hildegund C.J. Ertl, Honying Deng, Zhi Quan Xiang, Wynetta Giles-Davis, Insug O, Dariusz W. Kowalczyk, Magdalena Blaszczyk-Thurin
Publikováno v:
Cellular Immunology. 215:20-31
Different vaccine constructs based on DNA vaccines and viral recombinant vaccines expressing mouse p53 were compared for induction of protective immune responses to challenge with a sarcoma cell line that expresses high levels of mutated p53 protein.
Publikováno v:
Vaccine. 19:3583-3590
Protection to sexually transmitted infections with oncogenic human papillomaviruses (HPV) such as type 16 is thought to be provided by neutralizing antibodies directed to the major outer capsid protein, the L1 protein. A DNA vaccine and an E1-deleted
Autor:
Z. He, Wynetta Giles-Davis, Zhiquan Xiang, J. Cheng, Dariusz W Kowalczyk, Anthony P Wlazlo, Hildegund C.J. Ertl
Publikováno v:
Virology. 270:146-161
Most cancerous lesions of the uterine cervix are linked to persistent infections with human papillomaviruses (HPV), most notably HPV-16 or -18. Vaccine-induced immune responses to the HPV early antigens E6 and E7, which contribute to cell transformat
Autor:
K. John Pasi, Mark L. McCleland, Valder R. Arruda, Elina Armstrong, Roland W. Herzog, Katherine A. High, Dariusz W. Kowalczyk, Hildegund C. J. Ertl, J. Nathan Hagstrom, Paul A. Fields
Publikováno v:
Molecular Therapy. 1:225-235
Defining immune responses against the secreted transgene product in a gene therapy setting is critical for treatment of genetic diseases such as hemophilia B (coagulation factor IX deficiency). We have previously shown that intramuscular administrati