Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Dariusz Pytel"'
Autor:
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J. Nathaniel Diehl, Frank Tedeschi, Gao Zhou, Zhaofeng Gao, Samuel Flashner, Andres J. Klein-Szanto, Hanina Hibshoosh, Shimonosono Masataka, Olga S. Chajewski, Ireneusz Majsterek, Dariusz Pytel, Maria Hatzoglou, Channing J. Der, Hiroshi Nakagawa, Adam J. Bass, Kwok-Kin Wong, Serge Y. Fuchs, Anil K. Rustgi, Eckhard Jankowsky, J. Alan Diehl
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Cytoplasmic accumulation of RNA binding protein, hnRNPK in cancer cells is associated with poor prognosis. Here the authors show that SCFFbxo4 E3 ubiquitin ligase-mediated polyubiquitylation of hnRNPK restricts c-Myc translation and limits cancer pro
Externí odkaz:
https://doaj.org/article/fecd2f81e26b43a3b3aad7932728969f
Autor:
Natalia Siwecka, Wioletta Rozpędek-Kamińska, Adam Wawrzynkiewicz, Dariusz Pytel, J. Alan Diehl, Ireneusz Majsterek
Publikováno v:
Biomedicines, Vol 9, Iss 2, p 156 (2021)
Inositol-requiring enzyme type 1 (IRE1) is a serine/threonine kinase acting as one of three branches of the Unfolded Protein Response (UPR) signaling pathway, which is activated upon endoplasmic reticulum (ER) stress conditions. It is known to be cap
Externí odkaz:
https://doaj.org/article/d374311c497a48149ed539238b9886ad
Autor:
Dariusz Pytel, Yan Gao, Katarzyna Mackiewicz, Yuliya V Katlinskaya, Kirk A Staschke, Maria C G Paredes, Akihiro Yoshida, Shuo Qie, Gao Zhang, Olga S Chajewski, Lawrence Wu, Ireneusz Majsterek, Meenhard Herlyn, Serge Y Fuchs, J Alan Diehl
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006518 (2016)
The unfolded protein response (UPR) regulates cell fate following exposure of cells to endoplasmic reticulum stresses. PERK, a UPR protein kinase, regulates protein synthesis and while linked with cell survival, exhibits activities associated with bo
Externí odkaz:
https://doaj.org/article/4ced1db2d95a40098e3c80465969cbee
Autor:
Shikhar Mehrotra, Vamsi K. Gangaraju, J. Alan Diehl, Eduardo N. Maldonado, Paulo C. Rodriguez, Shilpak Chatterjee, Hong Li, Viswanathan Palanisamy, Stefano Berto, Hongjun Wang, Meenal Mehrotra, Lauren Ball, Gyda C. Beeson, Satish N. Nadig, Inhong Kang, Dariusz Pytel, Do-Sung Kim, Zachariah T. Hedley, Monika Gooz, Danh Tran, Seungho Choi, Rasesh Y. Parikh, Paramita Chakraborty
Mitochondria and endoplasmic reticulum (ER) share structural and functional networks and activate well-orchestrated signaling processes to shape cells’ fate and function. While persistent ER stress (ERS) response leads to mitochondrial collapse, mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03966e003aa062ef67f752a61daa01ba
https://doi.org/10.1158/0008-5472.c.6513793.v1
https://doi.org/10.1158/0008-5472.c.6513793.v1
Autor:
Shikhar Mehrotra, Vamsi K. Gangaraju, J. Alan Diehl, Eduardo N. Maldonado, Paulo C. Rodriguez, Shilpak Chatterjee, Hong Li, Viswanathan Palanisamy, Stefano Berto, Hongjun Wang, Meenal Mehrotra, Lauren Ball, Gyda C. Beeson, Satish N. Nadig, Inhong Kang, Dariusz Pytel, Do-Sung Kim, Zachariah T. Hedley, Monika Gooz, Danh Tran, Seungho Choi, Rasesh Y. Parikh, Paramita Chakraborty
Supplementary Figure from Carbon Monoxide Activates PERK-Regulated Autophagy to Induce Immunometabolic Reprogramming and Boost Antitumor T-cell Function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::327207eb3cc7721b863607a4a75d8d2b
https://doi.org/10.1158/0008-5472.22431067
https://doi.org/10.1158/0008-5472.22431067
Autor:
Tomasz Skorski, Janusz Blasiak, Michal O. Nowicki, Ewelina Stoczynska, Dariusz Pytel, Kimberly Cramer, Stanislaw K. Jozwiakowski, Tomasz Poplawski, Artur Slupianek
Supplementary Figures 1-4 from BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6087ab740ea7bc1beacd4deb08fdc1e5
https://doi.org/10.1158/0008-5472.22388429
https://doi.org/10.1158/0008-5472.22388429
Autor:
Tomasz Skorski, Janusz Blasiak, Michal O. Nowicki, Ewelina Stoczynska, Dariusz Pytel, Kimberly Cramer, Stanislaw K. Jozwiakowski, Tomasz Poplawski, Artur Slupianek
Supplementary Methods from BCR/ABL Stimulates WRN to Promote Survival and Genomic Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142bf8dafd6554cbe4cb49a2ab6e669d
https://doi.org/10.1158/0008-5472.22388426.v1
https://doi.org/10.1158/0008-5472.22388426.v1
Autor:
Paramita Chakraborty, Rasesh Y. Parikh, Seungho Choi, Danh Tran, Monika Gooz, Zachariah T. Hedley, Do-Sung Kim, Dariusz Pytel, Inhong Kang, Satish N. Nadig, Gyda C. Beeson, Lauren Ball, Meenal Mehrotra, Hongjun Wang, Stefano Berto, Viswanathan Palanisamy, Hong Li, Shilpak Chatterjee, Paulo C. Rodriguez, Eduardo N. Maldonado, J. Alan Diehl, Vamsi K. Gangaraju, Shikhar Mehrotra
Publikováno v:
Cancer Res
Mitochondria and endoplasmic reticulum (ER) share structural and functional networks and activate well-orchestrated signaling processes to shape cells’ fate and function. While persistent ER stress (ERS) response leads to mitochondrial collapse, mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f487e687c04379bfb56bd81f84eecce2
https://doi.org/10.1158/0008-5472.can-21-3155
https://doi.org/10.1158/0008-5472.can-21-3155
Autor:
Wioletta, Rozpedek-Kaminska, Danuta, Piotrzkowska, Grzegorz, Galita, Dariusz, Pytel, Ewa, Kucharska, Łukasz, Dziki, Adam, Dziki, Ireneusz, Majsterek
Publikováno v:
Polish Journal of Surgery. 94:17-25
Introduction: The newest data has reported that endoplasmic reticulum (ER) stress and PERK-dependent Unfolded Protein Response (UPR) signaling pathway may constitute a key factor in colorectal cancer (CRC) pathogenesis on the molecular level. Nowaday
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d47f914d3f78d03f954e9e586b943e
https://doi.org/10.5604/01.3001.0015.7948
https://doi.org/10.5604/01.3001.0015.7948
Cancer constitutes a grave problem nowadays in view of the fact that it has become one of the main causes of death worldwide. Poor clinical prognosis is presumably due to cancer cells metabolism as tumor microenvironment is affected by oxidative stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ae2c4366bd2cc5f954286598f146fe