Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Dariusz Kuśmierz"'
Autor:
Agnieszka Żak-Gołąb, Paweł Cieślik, Urszula Siekiera, Dariusz Kuśmierz, Antoni Hrycek, Michał Holecki
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5511 (2024)
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the production of autoantibodies against a lot of nuclear components. Despite many studies on the genetic background of this disease, the pathogenesis remains unclear
Externí odkaz:
https://doaj.org/article/9c38c87288e2490d8fb65f80a88c2552
Publikováno v:
BioTechnologia, Vol 103, Iss 1, Pp 29-39 (2022)
Juglone is an allelopathin secreted by black walnut tree of the Juglandaceae family and is used as an active in gre dient in many herbal preparations and as a commercial dye. It is considered as an important phytochemical with wide therapeutic potent
Externí odkaz:
https://doaj.org/article/0190183dfb2346adbb9a941f8d7e26e7
Autor:
Beata Morak-Młodawska, Krystian Pluta, Małgorzata Latocha, Małgorzata Jeleń, Dariusz Kuśmierz, Kinga Suwińska, Aleksander Shkurenko, Zenon Czuba, Magdalena Jurzak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1298-1306 (2019)
10H-1,9-diazaphenothiazine was obtained in the sulphurisation reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted derivatives, containing alkyl and dialkylaminoalkyl groups at the thiazine nitrogen atom. The 1,9-d
Externí odkaz:
https://doaj.org/article/11d1184f83e546758e3026d21f5efede
Autor:
Beata Morak-Młodawska, Krystian Pluta, Małgorzata Jeleń, Małgorzata Latocha, Dariusz Kuśmierz
Publikováno v:
Proceedings, Vol 22, Iss 1, p 85 (2019)
Cancer has now become a global problem and been ranked as the top leading cause of deathworldwide after cardiovascular disease [...]
Externí odkaz:
https://doaj.org/article/3be95246c3c64e169ab83d9f0a5f6256
Autor:
Beata Morak-Młodawska, Krystian Pluta, Małgorzata Latocha, Małgorzata Jeleń, Dariusz Kuśmierz
Publikováno v:
Molecules, Vol 24, Iss 2, p 267 (2019)
New 10-substituted derivatives of 3,6-diazaphenothiazine, containing the triple bond linker terminated with tertiary cyclic and acyclic amine groups, were synthesized and screened for their anticancer action. The compounds exhibited varied anticancer
Externí odkaz:
https://doaj.org/article/fecd422801a34bd19fbe53c08921551a
Autor:
Małgorzata Kapral, Joanna Wawszczyk, Katarzyna Jesse, Monika Paul-Samojedny, Dariusz Kuśmierz, Ludmiła Węglarz
Publikováno v:
Molecules, Vol 22, Iss 10, p 1657 (2017)
Abstract: AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays a critical role in the proliferation and resistance to apoptosis that are essential to the development and progression of colon cancer. Therefore, AKT/mTO
Externí odkaz:
https://doaj.org/article/153869f06b814bc791a61e7a6c1fcd6a
Publikováno v:
Molecules, Vol 21, Iss 11, p 1455 (2016)
A novel series of tetracyclic quinobenzothiazine derivatives was synthetized. Compounds containing a substituent (hydroxyl, methyl, phenyl, piperidyl, or piperazinyl) in positions 9 and 11 were obtained by cyclization of suitable 4-aminoquinolinium-3
Externí odkaz:
https://doaj.org/article/a54e0d8b704c4997a70ead973bb7a62d
Publikováno v:
Postępy Higieny i Medycyny Doświadczalnej. 76:132-142
Introduction Amygdalin is a chemical compound found in the seeds of many edible plants. Different studies using cancer cell cultures in vitro indicate its potential anti-cancer activity. Various types of cancer cells showed different responses to dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1550109ffc071bd607205f9c9926ca4b
https://doi.org/10.2478/ahem-2022-0013
https://doi.org/10.2478/ahem-2022-0013
Autor:
Beata Morak-Młodawska, Krystian Pluta, Małgorzata Latocha, Dariusz Kuśmierz, Małgorzata Jeleń, Kinga Suwińska
Publikováno v:
Bioorganic Chemistry. 87:810-820
We present efficient synthesis of isomeric types of angularly fused diquinothiazines in the reactions of 2,2′-dichloro-3,3′-diquinolinyl disulfide and diquinodithiin with 3-, 5-, 6- and 8-aminoquinolines. The pentacyclic diquinothiazine ring syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd36887c4d9d14289d7b343125c90453
https://doi.org/10.1016/j.bioorg.2019.04.005
https://doi.org/10.1016/j.bioorg.2019.04.005
Autor:
Małgorzata Latocha, Magdalena Jurzak, Aleksander Shkurenko, Krystian Pluta, Kinga Suwinska, Zenon P. Czuba, Beata Morak-Młodawska, Małgorzata Jeleń, Dariusz Kuśmierz
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1298-1306 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
10H-1,9-diazaphenothiazine was obtained in the sulphurisation reaction of diphenylamine with elemental sulphur and transformed into new 10-substituted derivatives, containing alkyl and dialkylaminoalkyl groups at the thiazine nitrogen atom. The 1,9-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ac3c5d467001451f7f33bfd4a11079
https://doaj.org/article/11d1184f83e546758e3026d21f5efede
https://doaj.org/article/11d1184f83e546758e3026d21f5efede