Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Dariusz Deredas"'
Publikováno v:
ARKIVOC, Vol 2018, Iss 3, Pp 120-133 (2018)
Externí odkaz:
https://doaj.org/article/ad4cf78f5b18409c94c3d60aa4d5c3ef
Synthesis of cyclopent-1-enecarbonitriles via a tandem Giese/HWE reaction initiated by visible light
Publikováno v:
Chemical Communications. 59:4372-4375
The manuscript describes studies on the radical tandem reaction involving Giese reaction followed by HWE olefination.
Publikováno v:
Molecular Biology Reports
Coumarin is a plant-derived compound but as such has no medical uses. Several synthetic coumarin analogs have been shown to possess anti-proliferative activity and to induce apoptosis in cancer cells. Here, we explored DNA damage responses in MCF-7 c
Autor:
Anna Janecka, Tomasz Janecki, Angelika Długosz, Dariusz Deredas, Katarzyna Gach-Janczak, Jacek Szymański
Publikováno v:
Pharmacological Reports. 70:631-638
Background The development of multidrug resistance to chemotherapy remains a challenge in the treatment of cancer and is a major factor causing failure of many forms of chemotherapy. The ATP binding cassette (ABC) family of proteins are efflux pumps
Publikováno v:
ARKIVOC, Vol 2018, Iss 3, Pp 120-133 (2018)
Publikováno v:
Tetrahedron Letters. 60:538-540
A strategically new approach to 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones is described. The protocol includes TMG promoted, conjugate addition of cyclohexane-1,3-diones to 3-(diethoxyphosphoryl)coumarins and a domino transesterification-cycl
Autor:
Angelika Długosz, Henryk Krawczyk, Tomasz Janecki, Dorota K. Pomorska, Marek Mirowski, Urszula Krajewska, Krzysztof Huben, Anna Janecka, Dariusz Deredas
Publikováno v:
MedChemComm. 7:1745-1758
A simple and general strategy for the synthesis of 3-methylene-4-(2-oxoalkyl)-3,4-dihydrocoumarins has been developed. The elaborated synthetic protocol includes 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD)- or Cs2CO3-promoted conjugate addition of enol
Publikováno v:
Tetrahedron. 70:8925-8929
A new approach to 3-(diethoxyphosphoryl)-4-(2-oxoalkyl)-3,4-dihydrocoumarins by base promoted conjugate addition of enolizable ketones to 3-(diethoxyphosphoryl)coumarin is described. The resulting products were transformed into the corresponding α-m
Autor:
Henryk Krawczyk, Dariusz Deredas, Tomasz Janecki, Anna Janecka, Jacek Szymański, Angelika Długosz, Katarzyna Gach-Janczak
Publikováno v:
Anti-cancer agents in medicinal chemistry. 18(3)
Background: Coumarin is a natural phytochemical but as such has no medical uses. However, various natural and synthetic coumarin analogs attract attention due to their interesting biological properties. Objective: Here, we evaluated and compared anti
Publikováno v:
Synthesis. 2012:247-252