Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Dariusz, Zakrzewicz"'
Autor:
Hongtao Liu, Dariusz Zakrzewicz, Kamil Nosol, Rossitza N. Irobalieva, Somnath Mukherjee, Rose Bang-Sørensen, Nora Goldmann, Sebastian Kunz, Lorenzo Rossi, Anthony A. Kossiakoff, Stephan Urban, Dieter Glebe, Joachim Geyer, Kaspar P. Locher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Cellular entry of the hepatitis B and D viruses (HBV/HDV) requires binding of the viral surface polypeptide preS1 to the hepatobiliary transporter Na+-taurocholate co-transporting polypeptide (NTCP). This interaction can be blocked by bulevi
Externí odkaz:
https://doaj.org/article/f9ddf8c868954a5d843a6783bfb948e5
Autor:
Dariusz Zakrzewicz, Regina Leidolf, Sebastian Kunz, Simon Franz Müller, Anita Neubauer, Silke Leiting, Nora Goldmann, Felix Lehmann, Dieter Glebe, Joachim Geyer
Publikováno v:
Viruses, Vol 14, Iss 6, p 1259 (2022)
Na+/taurocholate cotransporting polypeptide (NTCP, gene symbol SLC10A1) is a hepatic bile acid uptake carrier participating in the enterohepatic circulation of bile acids. Apart from its transporter function, NTCP acts as the high-affinity liver-spec
Externí odkaz:
https://doaj.org/article/f1e02be73de54cefa79e776777a2a09a
Autor:
Dariusz Zakrzewicz, Joachim Geyer
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 196 (2022)
Hepatitis B virus (HBV) infections are among the major public health concerns worldwide with more than 250 million of chronically ill individuals. Many of them are additionally infected with the Hepatitis D virus, a satellite virus to HBV. Chronic in
Externí odkaz:
https://doaj.org/article/750f2433596444b78ec4af95407669f8
Autor:
Anna Zakrzewicz, Katrin Richter, Dariusz Zakrzewicz, Kathrin Siebers, Jelena Damm, Alisa Agné, Andreas Hecker, J. Michael McIntosh, Walee Chamulitrat, Gabriela Krasteva-Christ, Ivan Manzini, Ritva Tikkanen, Winfried Padberg, Sabina Janciauskiene, Veronika Grau
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Interleukin-1β (IL-1β) is a potent, pro-inflammatory cytokine of the innate immune system that plays an essential role in host defense against infection. However, elevated circulating levels of IL-1β can cause life-threatening systemic inflammatio
Externí odkaz:
https://doaj.org/article/33801e27ed7e46ef8dc4ae7bde9ee513
Autor:
Dariusz Zakrzewicz, Joachim Geyer
Publikováno v:
Biological Chemistry.
Na+/taurocholate cotransporting polypeptide (NTCP) is a member of the solute carrier (SLC) family 10 transporters (gene symbol SLC10A1) and is responsible for the sodium-dependent uptake of bile salts across the basolateral membrane of hepatocytes. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5d1ddb926208f85b8d6e4d38b5e13c4
https://doi.org/10.1515/hsz-2022-0345
https://doi.org/10.1515/hsz-2022-0345
Autor:
Anca-Laura Amati, Anna Zakrzewicz, Kathrin Siebers, Sigrid Wilker, Sarah Heldmann, Dariusz Zakrzewicz, Andreas Hecker, J. Michael McIntosh, Winfried Padberg, Veronika Grau
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Chemokines and ATP are among the mediators of inflammatory sites that can enter the circulation via damaged blood vessels. The main function of chemokines is leukocyte mobilization, and ATP typically triggers inflammasome assembly. IL-1β, a potent i
Externí odkaz:
https://doaj.org/article/d24975298b7e47e288b2af11e18acd77
Autor:
Joachim Geyer, Dariusz Zakrzewicz
Publikováno v:
Biomedicines, Vol 10, Iss 196, p 196 (2022)
Hepatitis B virus (HBV) infections are among the major public health concerns worldwide with more than 250 million of chronically ill individuals. Many of them are additionally infected with the Hepatitis D virus, a satellite virus to HBV. Chronic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbed313460b412c04a5c8f16ce137cb2
https://www.mdpi.com/2227-9059/10/1/196
https://www.mdpi.com/2227-9059/10/1/196
Autor:
Dariusz, Zakrzewicz, Joachim, Geyer
Publikováno v:
Biomedicines
Hepatitis B virus (HBV) infections are among the major public health concerns worldwide with more than 250 million of chronically ill individuals. Many of them are additionally infected with the Hepatitis D virus, a satellite virus to HBV. Chronic in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::170884e7e759e6c8def423079ae4c42c
https://pubmed.ncbi.nlm.nih.gov/35052874
https://pubmed.ncbi.nlm.nih.gov/35052874
Autor:
Patrick Bulau, Dariusz Zakrzewicz, Kamila Kitowska, Birgit Wardega, Joachim Kreuder, Oliver Eickelberg
Publikováno v:
BioTechniques, Vol 40, Iss 3, Pp 305-310 (2006)
Arginine methylation constitutes a posttranslational modification dependent on the action of protein arginine methyltransferases (PRMTs). Using S-adenosylmethionine as a methyl donor, PRMTs catalyze the formation of monomethylarginine (L-NMMA), asymm
Externí odkaz:
https://doaj.org/article/50352d91bbfe46a994525a9851e16b82
Autor:
Nelli Baal, Ingrid Henneke, Grazyna Kwapiszewska, Leigh M. Marsh, Holger Hackstein, Dariusz Zakrzewicz, Marc W. Nolte, de Maat S, Martin Witzenrath, Malgorzata Wygrecka, Ralph T. Schermuly, Werner Seeger, Con Panousis, P. Markart, Lukasz Wujak, Katrin Reppe, Djuro Kosanovic, Miroslava Didiasova, Holger Müller-Redetzky, Helena Frey, Liliana Schaefer, Coen Maas
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 196:186-199
Acute respiratory distress syndrome is characterized by alveolar epithelial cell injury, edema formation, and intraalveolar contact phase activation.To explore whether C1 esterase inhibitor (C1INH), an endogenous inhibitor of the contact phase, may p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1f046f676262dfd92b1ed360955c85
https://doi.org/10.1164/rccm.201604-0712oc
https://doi.org/10.1164/rccm.201604-0712oc