Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Dariush, Honardoust"'
Autor:
Serge Goekjian, Edward E. Tredget, Jie Ding, Colin C. Anderson, Moein Momtazi, Dariush Honardoust, Peter Kwan
Publikováno v:
Plastic and Reconstructive Surgery. 136:1192-1204
Background Proliferative scars in nude mice have demonstrated morphologic and histologic similarities to human hypertrophic scar. Gene knockout technology provides the opportunity to study the effect of deleting immune cells in various disease proces
Autor:
Serge Goekjian, Edward E. Tredget, Dariush Honardoust, Moein Momtazi, Jie Ding, Peter Kwan, Colin C. Anderson
Publikováno v:
Wound Repair and Regeneration. 21:77-87
Hypertrophic scar (HSc) is a fibroproliferative disorder that occurs following deep dermal injury. Lack of a relevant animal model is one barrier toward better understanding its pathophysiology. Our objective is to demonstrate that grafting split-thi
Publikováno v:
Journal of Urology. 188:1543-1548
Partial bladder outlet obstruction has been shown in a rat model to progress from inflammation to hypertrophy to fibrosis. Small leucine-rich proteoglycans are extracellular matrix components associated with collagen fibrillogenesis and resultant sca
Publikováno v:
Journal of Burn Care & Research. 33:668-677
Hypertrophic scar (HTS) represents the dermal equivalent of fibroproliferative disorders. Fibroblasts from the deep dermis are implicated in the development of HTS after injuries that involve deeper areas of the skin. However, fibroblasts that reside
Autor:
Edward E. Tredget, Dariush Honardoust, Yvonne Marcoux, Jie Ding, Heather A. Shankowsky, Keijiro Hori, Rainny Zhang
Publikováno v:
Wound Repair and Regeneration. 19:568-578
Recent data support the involvement of stromal cell-derived factor 1 (SDF-1) in the homing of bone marrow-derived stem cells to wound sites during skeletal, myocardial, vascular, lung, and skin wound repair as well as some fibrotic disorders via its
Autor:
Keijiro Hori, Dariush Honardoust, Mathew Varkey, Jie Ding, Heather A. Shankowsky, Edward E. Tredget
Publikováno v:
Wound Repair and Regeneration. 19:368-378
Small leucine-rich proteoglycans (SLRPs) are extracellular matrix molecules that regulate collagen fibrillogenesis and inhibit transforming growth factor-β activity; thus, they may play a critical role in wound healing and scar formation. Hypertroph
Autor:
Jie Ding, Heather A. Shankowsky, Haiyan Jiao, Moein Momtazi, Edward E. Tredget, JianFei Wang, Dariush Honardoust
Publikováno v:
Wound Repair and Regeneration. 19:274-285
Hypertrophic scar (HTS) following thermal injury and other forms of trauma is a dermal fibroproliferative disorder that leads to considerable morbidity. Because of the lack of an ideal animal model, research is difficult. We have established an HTS m
Autor:
Humphrey Gardner, Dariush Honardoust, David A. Hart, Lari Häkkinen, Hannu Larjava, Corrie L. Gallant-Behm, Ameneh Eslami, Colin Wiebe
Publikováno v:
Journal of Histochemistry & Cytochemistry. 57:543-557
Oral mucosal wounds heal with reduced scar formation compared with skin. The epithelial integrin αvβ6 is induced during wound healing, and it can activate fibrogenic transforming growth factor β1 (TGF-β1) and anti-fibrogenic TGF-β3 that play key
Publikováno v:
Wound Repair and Regeneration. 16:814-823
Wound healing in oral mucosa is fast and results in little scar formation as compared with skin. The biological mechanisms underlying this property are poorly understood but may provide valuable information about the factors that promote wound regene
Publikováno v:
Journal of Neurochemistry. 102:153-169
Protein kinase B (Akt), glycogen synthase kinase-3 (GSK-3) and members of the Wnt signal transduction pathway were recently found to be altered in schizophrenia and targeted by antipsychotic drugs. In the current study, selected Wnt signalling protei