Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Darius Wlochowitz"'
Autor:
Kerstin Menck, Saskia Heinrichs, Darius Wlochowitz, Maren Sitte, Helen Noeding, Andreas Janshoff, Hannes Treiber, Torben Ruhwedel, Bawarjan Schatlo, Christian von der Brelie, Stefan Wiemann, Tobias Pukrop, Tim Beißbarth, Claudia Binder, Annalen Bleckmann
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Breast cancer has been associated with activation of the WNT signaling pathway, although no driver mutations in WNT genes have been found yet. Instead, a high expression of the alternative WNT receptor ROR2 was observed, in partic
Externí odkaz:
https://doaj.org/article/d0a5a0c967764391a19be071ba9a9dca
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Only 2% of glioblastoma multiforme (GBM) patients respond to standard therapy and survive beyond 36 months (long-term survivors, LTS), while the majority survive less than 12 months (short-term survivors, STS). To understand the mechanism leading to
Externí odkaz:
https://doaj.org/article/e15590b99d0c4ea5a178a487e7a161cd
Autor:
Bleckmann, Kerstin Menck, Darius Wlochowitz, Astrid Wachter, Lena-Christin Conradi, Alexander Wolff, Andreas Scheel, Ulrike Korf, Stefan Wiemann, Hans-Ulrich Schildhaus, Hanibal Bohnenberger, Edgar Wingender, Tobias Pukrop, Kia Homayounfar, Tim Beißbarth, Annalen
Publikováno v:
Cancers; Volume 14; Issue 9; Pages: 2084
Seventy percent of patients with colorectal cancer develop liver metastases (CRLM), which are a decisive factor in cancer progression. Therapy outcome is largely influenced by tumor heterogeneity, but the intra- and inter-patient heterogeneity of CRL
Autor:
Kerstin, Menck, Darius, Wlochowitz, Astrid, Wachter, Lena-Christin, Conradi, Alexander, Wolff, Andreas H, Scheel, Ulrike, Korf, Stefan, Wiemann, Hans-Ulrich, Schildhaus, Hanibal, Bohnenberger, Edgar, Wingender, Tobias, Pukrop, Kia, Homayounfar, Tim, Beißbarth, Annalen, Bleckmann
Publikováno v:
Cancers. 14(9)
Seventy percent of patients with colorectal cancer develop liver metastases (CRLM), which are a decisive factor in cancer progression. Therapy outcome is largely influenced by tumor heterogeneity, but the intra- and inter-patient heterogeneity of CRL
Autor:
Binder, Judith Buentzel, Henry Gerd Klemp, Ralph Kraetzner, Matthias Schulz, Gry Helene Dihazi, Frank Streit, Annalen Bleckmann, Kerstin Menck, Darius Wlochowitz, Claudia
Publikováno v:
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13540
Malignant cells differ from benign ones in their metabolome and it is largely unknown whether this difference is reflected in the metabolic profile of their microvesicles (MV), which are secreted into the blood of cancer patients. Here, they are pres
Autor:
Judith Buentzel, Henry Gerd Klemp, Ralph Kraetzner, Matthias Schulz, Gry Helene Dihazi, Frank Streit, Annalen Bleckmann, Kerstin Menck, Darius Wlochowitz, Claudia Binder
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 13540, p 13540 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 13540, p 13540 (2021)
Malignant cells differ from benign ones in their metabolome and it is largely unknown whether this difference is reflected in the metabolic profile of their microvesicles (MV), which are secreted into the blood of cancer patients. Here, they are pres
Autor:
Kerstin Menck, Torben Ruhwedel, Christian von der Brelie, Hannes Treiber, Claudia Binder, Saskia Heinrichs, Tim Beissbarth, Stefan Wiemann, Bawarjan Schatlo, Tobias Pukrop, Maren Sitte, Andreas Janshoff, Helen Noeding, Annalen Bleckmann, Darius Wlochowitz
Breast cancer has been associated with activation of the WNT signaling pathway, although the underlying molecular mechanisms are still unclear. Here, we found the WNT receptor ROR2 to be highly expressed in aggressive breast tumors and associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::021b6d7f91c5fafab03e2d1909da7730
https://doi.org/10.1101/2020.12.18.423402
https://doi.org/10.1101/2020.12.18.423402
Only 2% of Glioblastoma multiforme (GBM) patients respond to standard care and survive beyond 36 months (long-term survivors, LTS) while the majority survives less than 12 months (short-term survivors, STS). To understand the mechanism leading to poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b0f92f2b02529b95538501d71fc9f9
https://doi.org/10.20944/preprints202010.0046.v1
https://doi.org/10.20944/preprints202010.0046.v1
Autor:
Martin A. Proescholdt, Christina Hackl, Gunnar Müller, Julia Seegerer, Katja Dettmer, Michael P. Krahn, Christof Lenz, Claudia Binder, Britta Wenske, Annalen Bleckmann, Hanibal Bohnenberger, Marko Balkenhol, Christian Reimelt, Matthias Schulz, Deram Buyuktas, Peter J. Oefner, Uwe Karsten Hanisch, Hannes Treiber, Alonso Barrantes-Freer, Eva Rietkötter, Laila Siam, Dieter Kube, Lena Stange, Daniela Sparrer, Chistoph A Klein, Kirsten Utpatel, Elena Vollmer, Xueni Sun, Darius Wlochowitz, Markus J. Riemenschneider, Christine Stadelmann, Raquel Blazquez, Matthias Evert, Marian Grade, Tobias Pukrop
Publikováno v:
International Journal of Cancer
More than half of all brain metastases show infiltrating rather than displacing growth at the macro-metastasis/brain parenchyma interface (MMPI), a finding associated with shorter survival. The Lymphoid Enhancer-binding Factor-1 (LEF1) is an epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505ec960409000eec787e7c950e29123
http://resolver.sub.uni-goettingen.de/purl?gs-1/16874
http://resolver.sub.uni-goettingen.de/purl?gs-1/16874
Autor:
Annalen Bleckmann, Martin Proescholdt, Uwe Ritter, Astrid Wachter, Elena Vollmer, Raquel Blazquez, Darius Wlochowitz, Mathias Schulz, Eileen Reinz, Alexander Wolff, Gabriela Salinas, Júlia Perera-Bel, Marko Balkenhol, Kirsten Utpatel, Markus J. Riemenschneider, Christine Stadelmann, Hans-Ulrich Schildhaus, Ulrike Korf, Laila Siam, Uwe-Karsten Hanisch, Stefan Wiemann, Tim Beißbarth, Tobias Pukrop, Stefanie Seitz, Bawarjan Schatlo, Matthias Evert
Publikováno v:
Glia. 66(11)
Mutations and activation of the PI3K signaling pathway in breast cancer cells have been linked to brain metastases. However, here we describe that in some breast cancer brain metastases samples the protein expression of PI3K signaling components is r