Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Darius Vasco Köster"'
Autor:
Saravanan Palani, Sayantika Ghosh, Esther Ivorra-Molla, Scott Clarke, Andrejus Suchenko, Mohan K Balasubramanian, Darius Vasco Köster
Publikováno v:
eLife, Vol 10 (2021)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes st
Externí odkaz:
https://doaj.org/article/78426e233fe0474a809657362a0bda25
Autor:
Melissa Dewulf, Darius Vasco Köster, Bidisha Sinha, Christine Viaris de Lesegno, Valérie Chambon, Anne Bigot, Mona Bensalah, Elisa Negroni, Nicolas Tardif, Joanna Podkalicka, Ludger Johannes, Pierre Nassoy, Gillian Butler-Browne, Christophe Lamaze, Cedric M. Blouin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Caveolae are mechanosensors and mutations of their coat proteins are implicated in muscle disorders, but molecular mechanisms are unclear. Here, the authors show that caveolae can regulate IL6/STAT3 signaling in muscle cells under stress, and that dy
Externí odkaz:
https://doaj.org/article/af0a410ef64d4e98b3b78ef974859a6d
Autor:
Jonathon A Ditlev, Anthony R Vega, Darius Vasco Köster, Xiaolei Su, Tomomi Tani, Ashley M Lakoduk, Ronald D Vale, Satyajit Mayor, Khuloud Jaqaman, Michael K Rosen
Publikováno v:
eLife, Vol 8 (2019)
During T cell activation, biomolecular condensates form at the immunological synapse (IS) through multivalency-driven phase separation of LAT, Grb2, Sos1, SLP-76, Nck, and WASP. These condensates move radially at the IS, traversing successive radiall
Externí odkaz:
https://doaj.org/article/4967687a42254a76a7c714088eb669a4
The surface of a living cell provides a versatile active platform for numerous cellular processes, which arise from the interplay of the plasma membrane with the underlying actin cortex. In the past decades, reconstituted, minimal systems based on su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec1c36fce42ab2d73d8599fbaec8418
Autor:
Scott T. Clarke, Mohan K. Balasubramanian, Saravanan Palani, Sayantika Ghosh, Esther Ivorra-Molla, Andrejus Suchenko, Darius Vasco Köster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa892198c7753e3e42bb2442e298c6b3
https://doi.org/10.7554/elife.61078.sa2
https://doi.org/10.7554/elife.61078.sa2
Autor:
Holly R. Brooker, Juan Ramon Hernandez-Fernaud, Daniel P. Mulvihill, Taishi Kanamaru, Darius Vasco Köster, Saravanan Palani, Anton Kamnev, Jonathan B. A. Millar, Alexandra M. E. Jones, Mohan K. Balasubramanian, Tomoyuki Hatano
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology
Palani et al. reveal a new mechanism by which the F-actin binding protein tropomyosin is regulated. They find that phosphorylation of tropomyosin reduces its affinity for F-actin, allowing the competing Adf1 to bind and sever actin filaments.
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Autor:
Darius Vasco Köster, Sabeeha Malek
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The Ehlers-Danlos Syndromes (EDS) are a group of 13 disorders, clinically defined through features of joint hypermobility, skin hyperextensibility, and tissue fragility. Most subtypes are caused by mutations in genes affecting the structure or proces
Autor:
Sayantika Ghosh, Mohan K. Balasubramanian, Scott T. Clarke, Darius Vasco Köster, Esther Ivorra-Molla, Saravanan Palani, Andrejus Suchenko
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Actin filaments are central to numerous biological processes in all domains of life. Driven by the interplay with molecular motors, actin binding and actin modulating proteins, the actin cytoskeleton exhibits a variety of geometries. This includes st
Autor:
Darius Vasco Köster
Publikováno v:
Methods in Molecular Biology ISBN: 9781071607312
Here, we describe how to extract tethers or lipid membrane nanotubes from the plasma membrane of cells using optical tweezers. This technique allows measuring the force required to hold the membrane tether at a constant length, which is related to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bf1f00982cdf7f42caad76a800a03a
http://wrap.warwick.ac.uk/138625/1/WRAP-Pulling-tethers-cell-plasma-membrane-optical-tweezers-Koster-2020.pdf
http://wrap.warwick.ac.uk/138625/1/WRAP-Pulling-tethers-cell-plasma-membrane-optical-tweezers-Koster-2020.pdf
Publikováno v:
Science Advances
Stratified assembly of active components drives a tight huddle of proteins on the membrane.
Recent in vivo studies reveal that several membrane proteins are driven to form nanoclusters by active contractile flows arising from localized dynamic p
Recent in vivo studies reveal that several membrane proteins are driven to form nanoclusters by active contractile flows arising from localized dynamic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9c28794004d57015f29ca161350112
http://wrap.warwick.ac.uk/132301/13/WRAP-stratification-relieves-constraints-steric-hindrance-compact-asters-Das-2020.pdf
http://wrap.warwick.ac.uk/132301/13/WRAP-stratification-relieves-constraints-steric-hindrance-compact-asters-Das-2020.pdf