Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Darius N Lakdawalla"'
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction The U.S. Food and Drug Administration (FDA)'s guidances help describe the agency's current thinking on regulatory issues and serve as a means of informal policymaking that is non‐binding. This study examines the impact of two
Externí odkaz:
https://doaj.org/article/ccfa05ce0c8e46e28a0c63e0fded3f22
Publikováno v:
Journal of Benefit-Cost Analysis. :1-24
The generalized risk-adjusted cost-effectiveness (GRACE) analysis method modifies standard cost-effectiveness analysis (CEA), the primary method currently used worldwide to value health improvements arising from healthcare interventions. Generalizing
Publikováno v:
Value in Health. 25:1828-1836
Aduhelm is the first approved disease-modifying therapies (DMT) for Alzheimer disease (AD). Nevertheless, under current payment models, AD DMTs-especially because they treat broader populations-will pose challenges to patient access since costs may a
Publikováno v:
Value in Health.
Publikováno v:
Annals of Internal Medicine. 174:1700-1709
Background Fully assessing the mortality burden of the COVID-19 pandemic requires measuring years of life lost (YLLs) and accounting for quality-of-life differences. Objective To measure YLLs and quality-adjusted life-years (QALYs) lost from the COVI
Publikováno v:
The European Journal of Health Economics. 23:433-451
The generalized risk-adjusted cost-effectiveness (GRACE) model generalizes conventional cost-effectiveness analysis (CEA) by introducing diminishing returns to Health-Related Quality of Life (QoL). This changes CEA practice in three ways: (1) Willing
Autor:
Darius N. Lakdawalla, Katie Everson, Lauren M Zhao, Dominik Lautsch, Fang Sun, Joanna P. MacEwan, Larry Z. Liu
Publikováno v:
The American Journal of Managed Care. 27:162-168
Objectives To assess the evolving landscape of low-density lipoprotein cholesterol-lowering therapies (LLTs) and quantify their effect on cardiovascular disease (CVD)-related mortality and morbidity. Study design Secondary data came from LLT clinical
Publikováno v:
JAMA Network Open. 6:e2315823
ImportancePrior research suggests significant social value associated with increased longevity due to preventing and treating cancer. Other social costs associated with cancer, such as unemployment, public medical spending, and public assistance, may
Publikováno v:
Eur J Health Econ
Pharmaceuticals are priced uniformly by convention, but vary in their degree of effectiveness for different disease indications. As more high-cost therapies have launched, the demand for alternative payment models (APMs) has been increasing in many a
Autor:
Gary R, Lichtenstein, Ahva, Shahabi, Seth A, Seabury, Darius N, Lakdawalla, Oliver Díaz, Espinosa, Sarah, Green, Michelle, Brauer, Robert N, Baldassano
Publikováno v:
Gastroenterol Hepatol (N Y)
Patients with Crohn’s disease (CD) or ulcerative colitis (UC) have high morbidity rates owing to debilitating intestinal complications and extraintestinal manifestations (EIMs). We retrospectively identified patients in the Truven MarketScan databa